THYROTOXİCOSİS RELATED PSYCHOSİS: A CASE REPORT

Abstract

Hyperthyroidism is a clinical syndrome which may cause psychiatric symptoms like discomfort, motor or perceptive hyperactivity, emotional lability, sleep disorders, attention-concentration-memory problems, especially distractibility, hostile behaviours, anxiety, phobias, disphoria, paranoid and referansial thinking. In this report we present a 61-year-old male patient with encoherans, desorganisation, distorted reality testing who is diagnosed with hyperthyroidism. After receiving medication for hyperthyroidism, decrement in psychological findings were noted. Psychosis due to hyperthyroidism and its course were discussed in the light of previous reports in the literature.

Keywords

• Hyperthyroidism, psychosis, organic psychosis

Tirotoksikoza bağlı psikoz: olgu sunumu

Öz

hiperaktivite, emosyonel labilite, engellenme eşiğinde düşme, uyku bozukluğu, özellikle distraktibilite şeklinde olan dikkat ve konsantrasyonda bozulma, bellekte dikkat bozukluğuna ikincil bozulmalar, hostil davranışlar, anksiyete, fobi, disfori, paranoid ve referans fikirlerin baskın olduğu psikotik belirtiler ile gidebilen klinik bir tablodur. Bu yazımızda 61 yaşında enkoherans, belirgin dezorganizasyon, gerçeği değerlendirmede bozulma tablosuyla kliniğimize başvuran hastanın hipertiroidi tanısı almasının ardından hipertiroidinin tedavisiyle birlikte psikiyatrik durumunda belirgin düzelme olması üzerinden, hipertiroidiye bağlı psikoz ve seyri literatür bilgileri eşliğinde ele alınmıştır

Anahtar Kelimeler

• Hipertiroidizm, psikoz, organik psikoz

Kaynakça

1. Brownlie BE, Rae AM, Walshe JW ve ark (2000) Psychoses associated with thyrotoxicossis- "thyrotoxic psychosis". A report of 18 cases with statistical analysis of incidence. European Journal of Endocrinology, 142:438-444.
2. David A.S., Fleminger S., Kopelman MD, Lovestone S., Mellers JDC (2013) Lishman Organik Psikiyatri Nöropsikiyatri Ders Kitabı. İng. Çev. Yağcıoğlu AEA ve ark. Ankara: Pelikan Yayıncılık, 4:632-635
3. Gagliardi JP, Clary GL. Treatment of Thyrotoxicosis – Induced Psychosis. Psychopharmacology. Bulletin. 2002;36:7–13
4. Gelder M, Gath D (1996) Oxford Textbook of Psychiatry. Oxford: Oxford University Press, 3: 403.
5. Hendrix VC, Garrick TR (2000) Kaplan and Sadock’s Comprehensive Textbook of Psychiatry. Sadock BJ, Sadock VA (eds) Philadelphia: Lippincott Williams and Wilkins, 7:1808-1812.
6. Irwin R, Ellis PM, Delahunt J (1997) Psychosis following acute alteration of thyroid status. Aust N Z J Psychiatry, 31(5): 762-4.
7. Jadresic DP (1990) Psychiatric aspects of hyperthyroidism. J Psychosom Res; 34(6): 603-15.
8. Marian G, Nica AE, Lonescu BE, Ghinea D. (2009) J Med Life. 2009 Nov 15; 2(4): 440–442

9. Steinberg PI (1994)A case of paranoid disorder associated with hyperthyroidism.Can J Psychiatry, 39(3): 153-6