Effect Of Covid-19 On Pediatric Vital Signs

Öz

Background: Monitoring vital signs in children admitted to the emergency clinic is important for early diagnosis and prognosis of COVID-19. Objective: This study aims to determine the effect of Covid 19 on vital signs of children. Design and Setting: This is a retrospective cross-sectional descriptive study. The sample of the study consisted of 379 children from a public hospital in Istanbul. Methods: Fever, pulse rate, respiratory rate, SpO2, blood pressure, pain, blood glucose, site of pain, gastrointestinal system, cardiovascular, symptoms, respiratory system findings were analyzed. In addition, vital signs and descriptive characteristics were compared. Results: In the study, 52% of the children in the study group were girls, 53.6% aged between 13-18 years. 43.3% of the children had a temperature of 38.1°C and above, 48.5% had a heart rate of 101-150/min., 46.2% had a respiratory rate of 36-45/min, the SpO2 value of 48.3% was between 96-100, 51.5% had normal blood pressure, and 69.7% had pain. Blood sugar was found to be normal in 72.3% of children while 69.9% had sore throat, 63.3% muscle and joint pain, 41.2% abdominal pain, 51.7% nausea-vomiting, 41.4% diarrhea, 7.9% chest pain, 4.5% palpitations, 37.2% bronchitis, and 58.6% shortness of breath. Conclusion: Covid-19 has an impact on child's vital signs. Healthcare workers should know the effect of Covid-19 on children's vital signs in order to provide rapid and effective diagnosis, treatment and care for children admitted to emergency units.

Anahtar Kelimeler

• Child
• Covid-19
• Vital signs

Covid-19'un Pediatrik Yaşamsal Bulgular Üzerindeki Etkisi

Öz

Giriş: Acil servise başvuran çocuklarda COVID-19'un erken teşhisi ve prognozu için vital bulguların izlenmesi önemlidir. Amaç: Bu çalışmada, COVID-19'un çocukların vital bulguları üzerindeki etkisinin belirlenmesi amaçlanmıştır. Tasarım ve Ortam: Bu çalışma, retrospektif kesitsel tanımlayıcı bir çalışmadır. Çalışmanın örneklemini İstanbul'daki bir devlet hastanesindeki 379 çocuk hasta oluşturmuştur. Metot: Ateş, nabız, solunum hızı, SpO2, kan basıncı, ağrı, kan şekeri, ağrı yeri, gastrointestinal sistem, kardiyovasküler sistem, semptomlar, solunum sistemi bulguları analiz edilmiştir. Ayrıca, vital bulgular ve tanımlayıcı özellikler karşılaştırılmıştır. Bulgular: Çalışma grubundaki çocukların %52'si kız, %53,6'sı 13-18 yaş aralığında olduğu saptandı.Çocukların %43,3'ünün ateşi 38,1°C ve üzerinde, %48,5'inin kalp atış hızı 101-150/dk, %46,2'sinin solunum hızı 36-45/dk; çalışma grubunun %48,3'ünün SpO2 değeri 96-100 arasında, %51,5'inin kan basıncı normal ve %69,7'sinde ağrı olduğu saptandı. Çocukların %72,3'ünde kan şekeri normal bulunurken, %69,9'unda boğaz ağrısı, %63,3'ünde kas ve eklem ağrısı, %41,2'sinde karın ağrısı, %51,7'sinde bulantı-kusma, %41,4'ünde ishal, %7,9'unda göğüs ağrısı, %4,5'inde çarpıntı, %37,2'sinde bronşit ve %58,6'sında nefes darlığı görüldü. Sonuç: Covid-19, çocukların hayati belirtilerini etkilemektedir. Sağlık çalışanları, acil servislere kabul edilen çocuklara hızlı ve etkili tanı, tedavi ve bakım sağlamak için Covid-19'un çocukların hayati belirtileri üzerindeki etkisini bilmelidir.

Anahtar Kelimeler

• çocuk
• covid-19
• yaşam bulguları

Kaynakça

1. Boddu, S. K., Aurangabadkar, G., & Kuchay, M. S. (2020). New onset diabetes, type 1 diabetes and COVID-19. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 14(6), 2211–2217. https://doi.org/10.1016/j.dsx.2020.11.012
2. Chan, J. F., Yuan, S., Kok, K. H., To, K. K., Chu, H., Yang, J., Xing, F., Liu, J., Yip, C. C., Poon, R. W., Tsoi, H. W., Lo, S. K., Chan, K. H., Poon, V. K., Chan, W. M., Ip, J. D., Cai, J. P., Cheng, V. C., Chen, H., . . . Yuen, K. Y. (2020). A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster. The Lancet, 395(10223), 514–523. https://doi.org/10.1016/S0140-6736(20)30154-9
3. Choi, S. H., Kim, HW., Kang, J. M., Kim, D. H., & Cho, E. Y. (2020). Epidemiology and clinical features of coronavirus disease 2019 in children. Clinical and Experimental Pediatrics, 63(4), 125–132. https://doi.org/10.3345/cep.2020.00535
4. Demirçelik, Y., & Kanık, A. (2020). Çocuklarda Covid-19: Epidemiyoloji ve klinik bulgular [Covid-19 in children: Epidemiology and clinical features]. Tepecik Eğitim ve Araştırma Hastanesi Dergisi, 30(Ek Sayı), 58–62. https://doi.org/10.5222/terh.2020.60320
5. Dong, H., Gu, T. M., Zhu, B. Q., & Wu, J. (2023). Comparison of anthropometric parameters and laboratory test results before and after the COVID-19 outbreak among Chinese children aged 3–18 years. Frontiers in Public Health, 11, Article 1048087. https://doi.org/10.3389/fpubh.2023.1048087
6. Du, H., Dong, X., Zhang, J. J., Cao, Y. Y., Akdis, M., Huang, X. L., Chen, H. B., Yan, Y., Wang, Y., Zhou, Y. D., Guan, K., Gao, Y. D., Flaherty, S., Akdis, C. A., & Zhang, L. (2021). Clinical characteristics of 182 pediatric COVID-19 patients with different severities and allergic conditions. Allergy, 76(2), 510–532. https://doi.org/10.1111/all.14452
7. Eastin, C., & Eastin, T. (2020). Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China. Journal of Emergency Medicine, 58(4), 712–713. https://doi.org/10.1016/j.jemermed.2020.04.006
8. Fu, L., Wang, B., Yuan, T., Chen, X., Ao, Y., Fitzpatrick, T., Li, P., Zhou, Y., Lin, Y. F., Duan, Q., Luo, G., Fan, S., Lu, Y., Feng, A., Zhan, Y., Liang, B., Cai, W., Zhang, L., Du, X., . . . Zou, H. (2020). Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis. Journal of Infection, 80(6), 656–665. https://doi.org/10.1016/j.jinf.2020.03.041

9. Grant, M. C., Geoghegan, L., Arbyn, M., Mohammed, Z., McGuinness, L., Clarke, E. L., & Wade, R. G. (2020). The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries. PLoS ONE, 15(6), Article e0234765. https://doi.org/10.1371/journal.pone.0234765
10. Ho, C. S., Chee, C. Y., & Ho, R. C. (2020). Mental health strategies to combat the psychological impact of COVID-19 beyond paranoia and panic. Annals of the Academy of Medicine, Singapore, 49(3), 155–160. https://www.annals.edu.sg/pdf/49VolNo3Mar2020/V49N3p155.pdf
11. Hong, H., Wang, Y., Chung, H. T., & Chen, C. J. (2020). Clinical characteristics of novel coronavirus disease 2019 (COVID-19) in newborns, infants and children. Pediatrics and Neonatology, 61(2), 131–132. https://doi.org/10.1016/j.pedneo.2020.03.001
12. Kildegaard, H., Lund, L. C., Højlund, M., Stensballe, G., & Pottegård, A. (2022). Risk of adverse events after covid-19 in Danish children and adolescents and efficacy of BNT162b2 in adolescents: Cohort study. BMJ, 377, Article e068898. https://doi.org/10.1136/bmj-2021-068898
13. Lee, P. I., Hu, Y. L., Chen, P. Y., Huang, Y. C., & Hsueh, P. R. (2020). Are children less susceptible to COVID-19? Journal of Microbiology, Immunology and Infection, 53(3), 371–372. https://doi.org/10.1016/j.jmii.2020.02.011
14. Leidman, E., Duca, L. M., Omura, J. D., Proia, K., Stephens, J. W., & Foster, L. N. (2021). COVID-19 trends among persons aged 0–24 years — United States, March 1–December 12, 2020. MMWR. Morbidity and Mortality Weekly Report, 70(3), 88–94. https://doi.org/10.15585/mmwr.mm7003e1
15. Liu, Z., Bing, X., & Zhi, X. Z. (2020). The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Zhonghua Liu Xing Bing Xue Za Zhi, 41(2), 145–151. https://doi.org/10.3760/cma.j.issn.0254-6450.2020.02.003
16. Lu, Q., & Shi, Y. (2020). Coronavirus disease (COVID-19) and neonate: What neonatologist need to know. Journal of Medical Virology, 92(6), 564–567. https://doi.org/10.1002/jmv.25740
17. Lu, X., Xiang, Y., Du, H., & Wing-Kin Wong, G. (2020). SARS-CoV-2 infection in children — Understanding the immune responses and controlling the pandemic. Pediatric Allergy and Immunology, 31(5), 449–453. https://doi.org/10.1111/pai.13267
18. Ludvigsson, J. F. (2020). Children are unlikely to be main drivers of the COVID-19 pandemic — A systematic review. Acta Paediatrica, 109(8), 1525–1530. https://doi.org/10.1111/apa.15371
19. Ng, Y., Li, Z., Chua, Y. X., Chaw, W. L., Zhao, Z., Er, B., Pung, R., Chiew, C. J., Lye, D. C., & Lee, V. J. (2020). Evaluation of the effectiveness of surveillance and containment measures for the first 100 patients with COVID-19 in Singapore — January 2–February 29, 2020. MMWR. Morbidity and Mortality Weekly Report, 69(11), 307–311. https://doi.org/10.15585/mmwr.mm6911e1
20. Park, S. E. (2020). Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19). Clinical and Experimental Pediatrics, 63(4), 119–124. https://doi.org/10.3345/cep.2020.00493
21. Parri, N., Lenge, M., & Buonsenso, D. (2020). Children with Covid-19 in pediatric emergency departments in Italy. New England Journal of Medicine, 383(2), 187–190. https://doi.org/10.1056/NEJMc2007617
22. Patel, N. A. (2020). Pediatric COVID-19: Systematic review of the literature. American Journal of Otolaryngology, 41(5), Article 102573. https://doi.org/10.1016/j.amjoto.2020.102573
23. Petrosillo, N., Viceconte, G., Ergonul, O., Ippolito, G., & Petersen, E. (2020). COVID-19, SARS and MERS: Are they closely related? Clinical Microbiology and Infection, 26(6), 729–734. https://doi.org/10.1016/j.cmi.2020.03.026 Qiu, Y., Chen, X., & Shi, W. (2020). Impacts of social and economic factors on the transmission of coronavirus disease 2019 (COVID-19) in China. Journal of Population Economics, 33(4), 1127–1172. https://doi.org/10.1007/s00148-020-00778-2
24. Singhal, T. (2020). Review of coronavirus disease-2019 (COVID-19). The Indian Journal of Pediatrics, 87(4), 281–286. https://doi.org/10.1007/s12098-020-03263-6
25. Tittel, S. R., Rosenbauer, J., Kamrath, C., Ziegler, J. W., Reschke, F., Hammersen, J., ... & Holl, R. W. (2020). Did the COVID-19 lockdown affect the incidence of pediatric type 1 diabetes in Germany? Diabetes Care, 43(11), e172–e173. https://doi.org/10.2337/dc20-1633
26. Tullie, L., Ford, K., Bisharat, M., Watson, T., Morgan, J., & Giuliani, S. (2020). Gastrointestinal features in children with COVID-19: An observation of varied presentation in eight children. The Lancet Child & Adolescent Health, 4(7), e19–e20. https://doi.org/10.1016/S2352-4642(20)30165-6
27. UNICEF. (2023). Coronavirus disease (COVID-19): What parents should know. https://www.unicef.org/pacificislands/stories/coronavirus-diseasecovid-19-what-parents-should-know (Akiş tarihi: 10 Eylül 2023)
28. Viner, R. M., Ward, J. L., Hudson, L. D., Ashe, M., Patel, S. V., Hargreaves, D., & Whittaker, E. (2020). Systematic review of reviews of symptoms and signs of COVID-19 in children and adolescents. Archives of Disease in Childhood, 106(9), 880–887. https://doi.org/10.1136/archdischild-2020-320972
29. Wang, X. F., Yuan, J., Zheng, Y. J., Chen, J., Bao, Y. X., Wang, Y. F., ... & National Clinical Research Center for Respiratory Diseases (2020). Retracted: Clinical and epidemiological characteristics of 34 children with 2019 novel coronavirus infection in Shenzhen. Zhonghua Er Ke Za Zhi, 58(4), E008. https://doi.org/10.3760/cma.j.issn.0578-1310.2020.0008
30. World Health Organization. (2020). The use of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with COVID-19. https://www.who.int/news-room/commentaries/detail/the-use-of-non-steroidal-anti-inflammatory-drugs-(nsaids)-in-patients-with-covid-19 (Akiş tarihi: 10 Eylül 2023)
31. Yang, Y., Islam, M. S., Wang, J., Li, Y., & Chen, X. (2020). Traditional Chinese Medicine in the treatment of the novel coronavirus (SARS-CoV-2): A review and perspective. International Journal of Biological Sciences, 16(10), 1708–1717. https://doi.org/10.7150/ijbs.45538
32. Yasuhara, J., Kuno, T., Takagi, H., & Sumitomo, N. (2020). Clinical characteristics of COVID-19 in children: A systematic review. Pediatric Pulmonology, 55(10), 2565–2575. https://doi.org/10.1002/ppul.24991
33. Zhou, G. Y., Penwill, N. Y., Cheng, G., Xiong, X., & Zhang, Y. (2022). Utility of disease symptoms to predict COVID-19 infections in children. BMC Pediatrics, 22(1), Article 655. https://doi.org/10.1186/s12887-022-03729-w
34. Zhu, H., Wang, L., Fang, C., Peng, S., Zhang, L., Chang, G., ... & Zhou, W. (2020). Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Translational Pediatrics, 9(1), 51–60. https://doi.org/10.21037/tp.2020.02.06