Factors Associated With Complex Regional Pain Syndrome Type 1 After Distal Radius Fracture: A Retrospective Case–Control Study

Öz

Purpose: Complex regional pain syndrome type 1 (CRPS-1) is a debilitating clinical disorder. Although recent studies have provided increasing evidence regarding the pathophysiology of CRPS-1, the exact mechanisms remain unclear. Therefore, this study aimed to identify risk factors associated with CPRS-1 after non-operatively treated distal radius fractures. Methods: This retrospective case-control study included 24 female patients diagnosed with CRPS-1 following distal radius fracture and 24 female patients without a CRPS-1. Data on patients' age, duration of immobilization, pre-existing diseases before the fracture were recorded. Multivariate logistic regression analysis was performed to identify risk factors associated with CRPS-1. Results: Data from 48 female patients were analyzed. The CRPS-1 group was significantly older (57.7 ± 11.7 vs 50.3 ± 11.3 years, p=0.033). The number of patients with psychiatric disorders was higher in the CRPS-1 group (41.7%) vs 8.3%, p=0.008). Immobilization duration was longer in the CRPS-1 group (p=0.035). Multivariate analysis showed that psychiatric disorders significantly increased the risk of CRPS-1 (OR: 6.68 [95% CI 1.12-39.68 p=0.037]). Age, diabetes mellitus, and duration of immobilization were not statistically significant independent predictors of CRPS-1 development (p=0.142, p=0.892, p=0.139, respectively). Conclusion and Suggestions: Our results demonstrate that patients with psychiatric disorders have a higher risk of developing CRPS type I following DRF. Careful monitoring of these patients for CRPS-1 may provide opportunities for early preventive and therapeutic interventions, thereby reducing disability.

Anahtar Kelimeler

• CRPS-1;
• Psychiatric disorders
• Distal radius fractures

Distal Radius Kırığı Sonrası Kompleks Bölgesel Ağrı Sendromu Tip 1 İle İlişkili Faktörler: Retrospektif Vaka Kontrol Çalışması

Öz

Amaç: Kompleks bölgesel ağrı sendromu tip 1 (KBAS-1), yaşamı olumsuz etkileyen bir klinik bozukluktur. Son çalışmalar KBAS-1’in patofizyolojisi hakkında giderek artan kanıtlar sunsa da kesin mekanizmalar hala belirsizdir. Bu nedenle, bu çalışma, ameliyatsız tedavi edilen distal radius kırıklarından sonra KBAS-1 ile ilişkili risk faktörlerini belirlemeyi amaçlamıştır. Yöntem: Bu retrospektif vaka-kontrol çalışmasına, distal radius kırığı sonrası KBAS-1 tanısı konulan 24 kadın hasta ve KBAS-1 tanısı konulmayan 24 kadın hasta dahil edildi. Hastaların yaşı, immobilizasyon süresi ve kırık öncesi mevcut hastalıkları kaydedildi. KBAS-1 ile ilişkili risk faktörlerini belirlemek için çok değişkenli lojistik regresyon analizi yapıldı. Bulgular: 48 kadın hastadan elde edilen veriler analiz edildi. KBAS-1 grubu anlamlı derecede daha yaşlıydı (57,7 ± 11,7'ye karşı 50,3 ± 11,3 yıl, p=0,033). Psikiyatrik bozukluğu olan hasta sayısı KBAS-1 grubunda daha yüksekti (%41,7'ye karşı %8,3, p=0,008). İmmobilizasyon süresi KBAS-1 grubunda daha uzundu (p=0,035). Çok değişkenli analiz, psikiyatrik bozuklukların KBAS-1 riskini anlamlı derecede artırdığını gösterdi (OR: 6,68 [95% CI 1,12-39,68 p=0,037]). Yaş, diyabet mellitus ve immobilizasyon süresi, KBAS-1 gelişiminin istatistiksel olarak anlamlı bağımsız belirleyicileri değildi (sırasıyla p=0,142, p=0,892, p=0,139). Sonuç ve Öneriler: Bulgularımız, psikiyatrik bozuklukları olan hastaların distal radius kırıklarından sonra KBAS-1 geliştirme riskinin daha yüksek olduğunu göstermektedir. Bu hastaların KBAS-1 açısından dikkatli bir şekilde izlenmesi, erken önleyici ve tedavi edici müdahaleler için fırsatlar sağlayarak sakatlığı azaltabilir.

Anahtar Kelimeler

• KBAS-1
• Psikiyatrik Bozukluk
• Distal Radius kırıkları

Kaynakça

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