Glukokortikoidlere Bağlı Osteoporoz

Kadriye Öneş

Glukokortikoidlere Bağlı Osteoporoz

Öz

Sekonder osteoporozun en yaygın şekli olan glukokortikoid kaynaklı osteoporoz (GOP), önemli bir iyatrojenik problemi oluşturur. İlk aylarda %5 kemik kaybı meydana gelir. En fazla kırık vertebra, proksimal femur ve kostalarda görülür. GK kullanımı, kemik metabolizmasında önemli olan osteoblast ve osteoklast arasındaki dengeyi osteoklastlar lehine değiştirir. GK kullanımı kalsiyumun bağırsaklardan emilimini azaltmaktadır. Kalsiyumun renal alımında da azalma meydana gelir. Sonuçta kan kalsiyumunun azalması paratiroid hormon salınımını stimüle ederek kemik rezorpsiyonunu artırır. Glukokortikoidlerin kemik sağlığı üzerindeki olumsuz etkilerini önlemek veya en aza indirmek için tedavi hemen başlanmalıdır. D vitamini, kalsiyum takviyeleri ve bifosfonatlar tedavide kullanılmalıdır.

Anahtar Kelimeler

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

İç Hastalıkları

Bölüm

Konferans Bildirisi

Yazarlar

Kadriye Öneş ^* Bu kişi benim
Türkiye

Yayımlanma Tarihi

3 Mayıs 2019

Gönderilme Tarihi

5 Mart 2019

Kabul Tarihi

7 Nisan 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 11 Sayı: 3

IZ

https://izlik.org/JA53WJ53BP

Kaynak Göster

RIS / Bibtex

APA

Öneş, K. (2019). Glukokortikoidlere Bağlı Osteoporoz. Klinik Tıp Aile Hekimliği, 11(3), 99-102. https://izlik.org/JA53WJ53BP

AMA

1.Öneş K. Glukokortikoidlere Bağlı Osteoporoz. Aile Hekimliği. 2019;11(3):99-102. https://izlik.org/JA53WJ53BP

Chicago

Öneş, Kadriye. 2019. “Glukokortikoidlere Bağlı Osteoporoz”. Klinik Tıp Aile Hekimliği 11 (3): 99-102. https://izlik.org/JA53WJ53BP.

EndNote

Öneş K (01 Mayıs 2019) Glukokortikoidlere Bağlı Osteoporoz. Klinik Tıp Aile Hekimliği 11 3 99–102.

IEEE

[1]K. Öneş, “Glukokortikoidlere Bağlı Osteoporoz”, Aile Hekimliği, c. 11, sy 3, ss. 99–102, May. 2019, [çevrimiçi]. Erişim adresi: https://izlik.org/JA53WJ53BP

ISNAD

Öneş, Kadriye. “Glukokortikoidlere Bağlı Osteoporoz”. Klinik Tıp Aile Hekimliği 11/3 (01 Mayıs 2019): 99-102. https://izlik.org/JA53WJ53BP.

JAMA

1.Öneş K. Glukokortikoidlere Bağlı Osteoporoz. Aile Hekimliği. 2019;11:99–102.

MLA

Öneş, Kadriye. “Glukokortikoidlere Bağlı Osteoporoz”. Klinik Tıp Aile Hekimliği, c. 11, sy 3, Mayıs 2019, ss. 99-102, https://izlik.org/JA53WJ53BP.

Vancouver

1.Kadriye Öneş. Glukokortikoidlere Bağlı Osteoporoz. Aile Hekimliği [Internet]. 01 Mayıs 2019;11(3):99-102. Erişim adresi: https://izlik.org/JA53WJ53BP