Meme Kanserinin Diyet ve Yaşam Tarzı İle İlişkisi Nedir?

Yıl 2016, Cilt: 8 Sayı: 4, 29 - 32, 29.07.2016

Türkan Öztürk Topcu

Öz

Meme kanseri hem gelişmiş hem de gelişmekte olan ülkelerde kadınlar arasında görülen

en yaygın kanserdir ve dünya çapında sıklığı artmaktadır. Dünya Kanser Araştırma

Fonu [World Cancer Research Fund (WCRF)] ve Amerikan Kanser Derneği’nin kanser

önleme klavuzları; sağlıklı bir kilo, haftada 150 dakika egzersiz, alkol tüketiminin

kısıtlanması, bitkisel beslenme önerilerinde bulunmaktadır. Gözlemsel datalar, fiziksel

aktivitenin artırılması ve alkol tüketiminin kısıtlanmasıyla pre ve postmenapozal meme

kanseri gelişim riskinin azaldığını göstermiştir. Yeni ortaya çıkan datalar adelosan dönemde

sigara tüketiminin daha sonra meme kanseri gelişimine neden olabileceğini göstermiştir.

Yaşam tarzı değişikliği, BRCA mutasyonu olan bireylerde etkisi tam olarak bilinememekle

beraber , aile öyküsü olan yüksek riskli bireylerde ve genel toplumda modifiye

edilebilen bir risk faktörüdür. Yakın zamandaki uzman raporlarında başarılı bir şekilde

yapılabilen yaşam tarzı değişikliğinin erken erişkin ve adelosan dönemdeki tarama

yapılan normal popülasyondaki kadınlar ve yüksek riskli kadınlarda meme kanseri

gelişimini %25-30 oranında azaltığı gösterilmiştir.

Anahtar Kelimeler

meme kanseri, diyet, egzersiz

Kaynakça

• 1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. International journal of cancer Journal international du cancer. 2015;136(5):E359-86. 2. Anderson WF, Rosenberg PS, Petito L, Katki HA, Ejlertsen B, Ewertz M, et al. Divergent estrogen receptor-positive and -negative breast cancer trends and etiologic heterogeneity in Denmark. International journal of cancer Journal international du cancer. 2013;133(9):2201-6. 3. Hou N, Huo D. A trend analysis of breast cancer incidence rates in the United States from 2000 to 2009 shows a recent increase. Breast cancer research and treatment. 2013;138(2):633-41. 4. Sestak I. Preventative therapies for healthy women at high risk of breast cancer. Cancer management and research. 2014;6:423-30. 5. Litzenburger BC, Brown PH. Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. Current breast cancer reports. 2014;6:96-109. 6. Vrieling A, Buck K, Kaaks R, Chang-Claude J. Adult weight gain in relation to breast cancer risk by estrogen and progesterone receptor status: a meta-analysis. Breast cancer research and treatment. 2010;123(3):641-9. 7. Eliassen AH, Colditz GA, Rosner B, Willett WC, Hankinson SE. Adult weight change and risk of postmenopausal breast cancer. Jama. 2006;296(2):193-201. 8. Scoccianti C, Lauby-Secretan B, Bello PY, Chajes V, Romieu I. Female breast cancer and alcohol consumption: a review of the literature. American journal of preventive medicine. 2014;46(3 Suppl 1):S16-25. 9. Chen P, Li C, Li X, Li J, Chu R, Wang H. Higher dietary folate intake reduces the breast cancer risk: a systematic revi32 www.kliniktipdergisi.com ew and meta-analysis. British journal of cancer. 2014; 110(9):2327-38. 10. Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee IM, et al. American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Medicine and science in sports and exercise. 2011;43(7):1334-59. 11. Wu Y, Zhang D, Kang S. Physical activity and risk of breast cancer: a meta-analysis of prospective studies. Breast cancer research and treatment. 2013;137(3):869-82. 12. Lynch BM, Neilson HK, Friedenreich CM. Physical activity and breast cancer prevention. Recent results in cancer research Fortschritte der Krebsforschung Progres dans les recherches sur le cancer. 2011;186:13-42. 13. Neilson HK, Conroy SM, Friedenreich CM. The Influence of Energetic Factors on Biomarkers of Postmenopausal Breast Cancer Risk. Current nutrition reports. 2014;3:22-34. 14. Leenders M, Sluijs I, Ros MM, Boshuizen HC, Siersema PD, Ferrari P, et al. Fruit and vegetable consumption and mortality: European prospective investigation into cancer and nutrition. American journal of epidemiology. 2013;178(4):590-602. 15. Norat T, Aune D, Chan D, Romaguera D. Fruits and vegetables: updating the epidemiologic evidence for the WCRF/AICR lifestyle recommendations for cancer prevention. Cancer treatment and research. 2014;159:35-50. 16. Aune D, Chan DS, Greenwood DC, Vieira AR, Rosenblatt DA, Vieira R, et al. Dietary fiber and breast cancer risk: a systematic review and meta-analysis of prospective studies. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 2012;23(6):1394-402. 17. Alexander DD, Mink PJ, Cushing CA, Sceurman B. A review and meta-analysis of prospective studies of red and processed meat intake and prostate cancer. Nutrition journal. 2010;9:50. 18. Alexander DD, Weed DL, Cushing CA, Lowe KA. Meta-analysis of prospective studies of red meat consumption and colorectal cancer. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation. 2011;20(4):293-307. 19. Dewi FN, Wood CE, Lees CJ, Willson CJ, Register TC, Tooze JA, et al. Dietary soy effects on mammary gland development during the pubertal transition in nonhuman primates. Cancer prevention research. 2013;6(8):832-42. 20. Cooper C, Sommerlad A, Lyketsos CG, Livingston G. Modifiable predictors of dementia in mild cognitive impairment: a systematic review and meta-analysis. The American journal of psychiatry. 2015;172(4):323-34. 21. Schwingshackl L, Missbach B, Konig J, Hoffmann G. Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis. Public health nutrition. 2015;18(7):1292-9. 22. Kim EH, Willett WC, Fung T, Rosner B, Holmes MD. Diet quality indices and postmenopausal breast cancer survival. Nutrition and cancer. 2011;63(3):381-8. 23. Dolara P, Bigagli E, Collins A. Antioxidant vitamins and mineral supplementation, life span expansion and cancer incidence: a critical commentary. European journal of nutrition. 2012;51(7):769-81. 24. Reynolds P. Smoking and breast cancer. Journal of mammary gland biology and neoplasia. 2013;18(1):15-23. 25. Tryggvadottir L, Sigvaldason H, Olafsdottir GH, Jonasson JG, Jonsson T, Tulinius H, et al. Population-based study of changing breast cancer risk in Icelandic BRCA2 mutation carriers, 1920-2000. Journal of the National Cancer Institute. 2006;98(2):116-22. 26. Orr N, Dudbridge F, Dryden N, Maguire S, Novo D, Perrakis E, et al. Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2. Human molecular genetics. 2015;24(10):2966-84. 27. Vrieling A, Kampman E. The role of body mass index, physical activity, and diet in colorectal cancer recurrence and survival: a review of the literature. The American journal of clinical nutrition. 2010;92(3):471-90. 28. Emaus MJ, van Gils CH, Bakker MF, Bisschop CN, Monninkhof EM, Bueno-de-Mesquita HB, et al. Weight change in middle adulthood and breast cancer risk in the EPIC-PANACEA study. International journal of cancer Journal international du cancer. 2014;135(12):2887-99. 29. Parkin DM, Boyd L, Walker LC. 16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010. British journal of cancer. 2011;105 Suppl 2:S77-81.