Öz
Abstract
Background: The most common types of intradural tumors are ependymoma andschwannomma. These are rarely seen together at the same time. This cooccurence isoften associated with a syndrome called neurofibromatosis (NF).
Case presentation: A 38-years-old female patient, who complained of back pain. Oncontrast enhanced spinal MR imaging, two lesion were detected. Immunohistochemical examination showed that the first lesion was schwannoma, whereas the second lesion was myxopapillary ependymoma.
Discussion:Ependymoma and schwannoma are rarely seen together at the same time,which often associated with NF.Conclussion: This cooccurence should remind genetic disorders such as neurofib-romatosis and should be investigated for other tumors.
Anahtar Kelimeler
Kaynakça
- Kaynaklar 1.Burton M, Mesfin F. Cancer, Conus And Cauda Equina, Tu-mors. Treasure Island (FL): StatPearls Publishing; 2017 Jun 2.Wood WG, Rothman LM, Nussbaum BE. Intramedullary neu-rilemoma of the cervical spinal cord. Case report. J Neuro-surg1975;42:465–468 3.Kim DG, Paek SH, Chi JG, Chun YK, Han DH. Mixed tumo-ur of schwannoma and meningioma components in a patientwith NF-2. ActaNeurochir (Wien). 1997;139: 1061-1064. 4.Elizabeth J, Menon G, Nair S, Radhakrishnan VV. Mixed tu-mour of schwannoma and meningioma in a patient with neu-rofibromatosis-2: a case report. NeurolIndia. 2001;49:398-400. 5.Gelal F, Rezanko T, Uyaroglu MA, Tunakan M, BezirciogluH. Islets of meningioma in an acoustic schwannoma in a pa-tient with neurofibromatosis-2: pathology and magnetic re-sonance imaging findings. ActaRadiol. 2005;46:519-522. 6.Davidoff LM, Martin J. Hereditary combined neurinomas andmeningiomas. J Neurosurg. 1955;12:375-384 7.Two distinct primary brain tumors, in same region of the samepatient: a case report. Tugcu B, Kepoglu U, Gunal M, Gunal-di O, Karakaya B, Demirgil BT.J Neurooncol. 2006Sep;79(2):219-20. 8.Rasheed, F., Fatima, S., &Ahmad, Z. (2016). Triad of Intras-pinal Meningioma, Schwannoma, and Ependymoma: Reportof an Extremely Rare Case. International journal of surgicalpathology, 24(1), 55-58. 9.Tanriverdi, T.,Abuzayed, B., Hanimoglu, H., Oz, B., &Han-ci, M. (2005). Concomitant ependymoma and schwannoma ofthe lumbar spine without neurofibromatosis. Neurosurgery-Quarterly, 15(3), 178-180.
Öz
Öz
Giriş:İntradural ekstramedüller tümörler içerisinde en sık görülenlerden ikisi epandimom ve schwannomdur. Bu tümörlerin aynı anda birlikte görülmesi oldukça nadir bir durumdur. Bu birliktelik genellikle nörofibromatozis(NF) gibi sendromlarla ilişkilendirilmiştir.
Olgu sunumu: 38 yaşında kadın hasta, bel ağrısı şikayeti ile başvurdu. Lomber MR’daintradural 2 adet kitle izlendi. Operasyon sonrası kitlelerden biri epandimom, diğeri schwannom olarak rapor edildi.
Tartışma: Epandimom ve schwannom birlikteliği nadir görülür. Genellikle NF ileilişkilidir.
Sonuç: Tümör supressör genlerde bir defekt olabileceğinden bu hastalar, diğer tümörler açısından yakın takip altına alınmalıdır.
Anahtar Kelimeler
Kaynakça
- Kaynaklar 1.Burton M, Mesfin F. Cancer, Conus And Cauda Equina, Tu-mors. Treasure Island (FL): StatPearls Publishing; 2017 Jun 2.Wood WG, Rothman LM, Nussbaum BE. Intramedullary neu-rilemoma of the cervical spinal cord. Case report. J Neuro-surg1975;42:465–468 3.Kim DG, Paek SH, Chi JG, Chun YK, Han DH. Mixed tumo-ur of schwannoma and meningioma components in a patientwith NF-2. ActaNeurochir (Wien). 1997;139: 1061-1064. 4.Elizabeth J, Menon G, Nair S, Radhakrishnan VV. Mixed tu-mour of schwannoma and meningioma in a patient with neu-rofibromatosis-2: a case report. NeurolIndia. 2001;49:398-400. 5.Gelal F, Rezanko T, Uyaroglu MA, Tunakan M, BezirciogluH. Islets of meningioma in an acoustic schwannoma in a pa-tient with neurofibromatosis-2: pathology and magnetic re-sonance imaging findings. ActaRadiol. 2005;46:519-522. 6.Davidoff LM, Martin J. Hereditary combined neurinomas andmeningiomas. J Neurosurg. 1955;12:375-384 7.Two distinct primary brain tumors, in same region of the samepatient: a case report. Tugcu B, Kepoglu U, Gunal M, Gunal-di O, Karakaya B, Demirgil BT.J Neurooncol. 2006Sep;79(2):219-20. 8.Rasheed, F., Fatima, S., &Ahmad, Z. (2016). Triad of Intras-pinal Meningioma, Schwannoma, and Ependymoma: Reportof an Extremely Rare Case. International journal of surgicalpathology, 24(1), 55-58. 9.Tanriverdi, T.,Abuzayed, B., Hanimoglu, H., Oz, B., &Han-ci, M. (2005). Concomitant ependymoma and schwannoma ofthe lumbar spine without neurofibromatosis. Neurosurgery-Quarterly, 15(3), 178-180.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 30 Ocak 2018 |
| Yayımlandığı Sayı | Yıl 2018 Cilt: 10 Sayı: 1 |
