Evaluation Of Helicobacter pylori Antigen Positivity İn Stool Samples Of Patients With Dyspeptic Complaints

Öz

Abstract Helicobacter pyloriis a bacterium that has been implicated in the gastrointestinal tractand responsible for important clinical tables throughout mankind history. There is a strongrelationship between gastric cancer and H.pyloripositivity. In this study, we intendedto establish the positivity rate of H.pyloriantigen in stool samples of outpatients withdyspeptic complaints and to evaluate its relation with age and gender. Between January 01, 2014 and February 28, 2018, stool samples of 1142 outpatients with dyspepticcomplaints admitted to various departments are investigated with an immunochromatographic test kit using monoclonal antibodies for detection of H.pyloriantigen. The results were evaluated retrospectively. Among 1142 patients’ stool samples tested, 125(10.9%) were positive. Among all cases, 740 (64.7%) were under 40 years of age. 35.2%of men and 64.8% of women were detected as positive. According to age groups, 40% patients were positive for 20-40 age groups. When compared with other studies in Turkey, it is a pleasing result to detect a lower rate of positivity.

Anahtar Kelimeler

• Helicobacter pylori,H.pyloristool antigen test,epidemiology

Dispeptik Yakınmaları Olan Hastaların Dışkı Örneklerinde Helicobacter pylori Antijen Pozitifliğinin Değerlendirilmesi

Öz

Öz

Helicobacter pyloriinsanlık tarihi boyunca gastrointestinal sistemde yerleşen ve önemli klinik tablolardan sorumlu bir bakteridir. Gastrik kanser ile H.pyloripozitifliği arasında güçlü bir ilişki olduğu kanıtlanmıştır. Bu çalışmada, dispeptik yakınmalara sahip hastaların dışkı örneklerinde H.pyloriantijeninin pozitiflik oranını belirlemek ve yaş ve cinsiyet ile olan ilişkisini değerlendirmek amaçlanmıştır. Ocak 2014–Şubat 2018 tarihleri arasında, dispeptik yakınmaları nedeniyle çeşitli polikliniklere başvuran 1142 hastanın gaita örneği, H.pyloriantijeninin tespiti için monoklonal antikor içeren immunokromatografik test kitleri ile araştırılmıştır. Sonuçlar retrospektif olarak değerlendirilmiştir. İncelenen gaita örnekleri arasında 125/1142 (%10.9)'si immunoassay yöntemiyle pozitif olarak sonuçlandı. Olguların 740 (%64.7)'ı 40 yaşından küçüktür. Sonucu pozitifolan olguların 44 (%35.2)'ü erkek, 81 (%64.8)'i kadın idi. Özellikle 20-40 yaş aralığın-da 50 pozitif hasta (%40) tespiti ile tüm yaş grupları arasında en yüksek oran bulunmuştur. Türkiye’den diğer çalışmalar ile kıyaslandığı zaman, daha düşük pozitiflik oranı tespit edilmesi sevindirici bir sonuçtur

Anahtar Kelimeler

• Helicobacter pylori,H.pylorigaita antijen testi,epidemiyoloji

Kaynakça

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