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Current Pharmacological Treatment Algorithmin Type 2 Diabetes

Yıl 2017, Cilt: 5 Sayı: 4, 71 - 75, 10.04.2017

Öz

Abstract

A patient-centered approach should be used to guide the choice of pharmacologic agentsand for glycemic goal in Type 2 DM. Considerations include efficacy, hypoglycemiarisk, impact on weight, potential side effects, cost and patient preferences. Lifestyle modifications that improve health care should be emphasized along with any pharmacologic therapy. For patients with type 2 diabetes who are not achieving glycemic goals, insulin therapy should not be delayed..

Kaynakça

  • Kaynaklar 1.Cornell S. Comparison of the diabetes guidelines from the ADA/EASDand the AACE/ACE J Am Pharm Assoc (2003). 2017;57(2):261-265. 2.Marathe, P.H., et al,American Diabetes Association Standards of Me-dical Care in Diabetes 2017. Diabetes Care 2017,40(Suppl. 1):66 3.Rodbard HW, Jellinger PS, Davidson JA, Einhorn D, et al. Statementby American Association of Clinical Endocrinologists/ American Col-lege of Endocrinology Consensus Panel on Type 2 Diabetes Mellitus:An algorithm for glycemic control. Endocr Pract 2009;15:540-59. 4.Canadian Diabetes Association. 2008 Clinical Practice Guidelinesfor the Prevention and Management of Diabetes in Canada. Cana-dian J Diabetes 2008;32(Suppl. 1):1-215. 5.National Institute for Health and Clinical Excellence (NICE). Type 2diabetes: the management of type 2 diabetes. 2008. (www.nice. org.uk). 6.Nathan DM, Buse JB, Davidson MB, et al. Medical management ofhyperglycemia in type 2 diabetes -a consensus algorithm for the ini-tiation and adjustment of therapy: a consensus statement of the Ame-rican Diabetes Association and the European Association for the Studyof Diabetes. Diabetes Care 2009;32:193–203. 7.Diabetes Mellitus ve Komplikasyonlarının Tanı,Tedavi ve İzlem Kı-lavuzu-2016 8.Palmer SC, Mavridis D, Nicolucci A, et al. Comparison of clinicaloutcomes and adverse events associated with glucose-lowering drugsin patients with type 2 diabetes: a meta-analysis. JAMA2016;316:313–324 9. Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HAW. 10-yearfollow-up of intensive glucose control in type 2 diabetes.N Engl J Med2008;359: 1577–1589 10. Bennett WL, Maruthur NM, Singh S, et al. Comparative effectivenessand safety of medications for type 2 diabetes: an update includingnew drugs and 2-drug combinations. Ann Intern Med2011;154:602–613 11. Aroda VR, Edelstein SL, Goldberg RB, et al.; Diabetes PreventionProgram Research Group.Long-term metformin use and vitamin B12defi- ciency in the Diabetes Prevention Program Outcomes Study.J Clin Endocrinol Metab 2016;101: 1754–1761 12. Inzucchi SE, Bergenstal RM, Buse JB, et al. Management ofhyperglycemia in type 2 diabetes, 2015: a patient-centered appro-ach: update to a position statement of the American Diabetes Asso-ciation and the European Association for the Study of Diabetes. Dia-betes Care 2015;38:140–149 13. Chiasson J-L, Josse RG, Hunt JA, et al.The efficacy of acarbose inthe treatment of patients with non-insulin-dependent diabetes mel-litus. A multicenter controlled clinical trial. Ann Intern Med1994;121:928-35. 14. Kahn SE, Haffner SM, Heise MA, et al. Glycemic durability of ro-siglitazone, metformin, or glyburide monotherapy. N Engl J Med2006;355:2427-43. 15. UK Prospective Diabetes Study (UKPDS) Group. Effect of intensi-ve blood-glucose control with metformin on complications in over-weight patients with type 2 diabetes (UKPDS 34). Lancet1998;352:854-65. 16. Fakhoury WK, Lereun C, Wright D. A meta-analysis of placebo-con-trolled clinical trials assessing the efficacy and safety of incretinba-sed medications in patients with type 2 diabetes. Pharmacology2010;86:44-57. 17. Fonseca V, Rosenstock J, Patwardhan R, et al. Effect of metformin androsiglitazone combination therapy in patients with type 2 diabetes mel-litus: a randomized controlled trial. JAMA 2000;283:1695-702 18. Diamant M, Nauck MA, Shaginian R, et al.; 4B Study Group. Glu-cagon-like peptide 1 receptor agonist or bolus insulin with optimi-zed basal insulin in type 2 diabetes. Diabetes Care 2014;37:2763–2773 19. Eng C, Kramer CK, Zinman B, Retnakaran R. Glucagon-like pepti-de-1 receptor agonist and basal insulin combination treatment forthe management of type 2 diabetes: a systematic review and meta-analysis. Lancet 2014;384: 2228–2234 20. Mathieu C, Storms F, Tits J, Veneman TF, Colin IM. Switching frompremixed insulin to basal-bolus insulin glargine plus rapid-actinginsulin: the ATLANTIC study. Acta Clin Belg 2013; 68:28–33 21. Dieuzeide G, Chuang L-M, Almaghamsi A, Zilov A, Chen J-W, La-valle-Gonzalez FJ. Safety ´ and effectiveness of biphasic insulin as-part 30 in people with type 2 diabetes switching from basal-bolus in-sulin regimens in the A1chieve study. Prim Care Diabetes2014;8:111–117 22. Giugliano D, Chiodini P, Maiorino MI, Bellastella G, Esposito K.Intensification of insulin therapy with basal-bolus or premixed in-sulin regimens in type 2 diabetes: a systematic review and meta-analy-sis of randomized controlled trials. Endocrine 2016;51:417–428

Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması

Yıl 2017, Cilt: 5 Sayı: 4, 71 - 75, 10.04.2017

Öz

Öz

Tip 2 DM tedavisinde güncel yaklaşım; glisemik kontrol hedeflerinin ve kullanılacak farmakolojik ajanların seçiminin hasta merkezli olması yönündedir. Bununla birlikte seçilecek ilacın etkinliği, hipoglisemi riski, kilo üzerine etkisi, muhtemel yan etkileri, maliyet ve hasta tercihleri de tedavi planında dikkate alınmalıdır. Yaşam tarzı değişiklikleri,uygulanacak  farmakolojik tedavi ne olursa olsun tedaviye eklenmelidir. Glisemik hedeflere ulaşılamayan tip 2 diyabet hastalarında insülin tedavisi geciktirilmemelidir.

Kaynakça

  • Kaynaklar 1.Cornell S. Comparison of the diabetes guidelines from the ADA/EASDand the AACE/ACE J Am Pharm Assoc (2003). 2017;57(2):261-265. 2.Marathe, P.H., et al,American Diabetes Association Standards of Me-dical Care in Diabetes 2017. Diabetes Care 2017,40(Suppl. 1):66 3.Rodbard HW, Jellinger PS, Davidson JA, Einhorn D, et al. Statementby American Association of Clinical Endocrinologists/ American Col-lege of Endocrinology Consensus Panel on Type 2 Diabetes Mellitus:An algorithm for glycemic control. Endocr Pract 2009;15:540-59. 4.Canadian Diabetes Association. 2008 Clinical Practice Guidelinesfor the Prevention and Management of Diabetes in Canada. Cana-dian J Diabetes 2008;32(Suppl. 1):1-215. 5.National Institute for Health and Clinical Excellence (NICE). Type 2diabetes: the management of type 2 diabetes. 2008. (www.nice. org.uk). 6.Nathan DM, Buse JB, Davidson MB, et al. Medical management ofhyperglycemia in type 2 diabetes -a consensus algorithm for the ini-tiation and adjustment of therapy: a consensus statement of the Ame-rican Diabetes Association and the European Association for the Studyof Diabetes. Diabetes Care 2009;32:193–203. 7.Diabetes Mellitus ve Komplikasyonlarının Tanı,Tedavi ve İzlem Kı-lavuzu-2016 8.Palmer SC, Mavridis D, Nicolucci A, et al. Comparison of clinicaloutcomes and adverse events associated with glucose-lowering drugsin patients with type 2 diabetes: a meta-analysis. JAMA2016;316:313–324 9. Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HAW. 10-yearfollow-up of intensive glucose control in type 2 diabetes.N Engl J Med2008;359: 1577–1589 10. Bennett WL, Maruthur NM, Singh S, et al. Comparative effectivenessand safety of medications for type 2 diabetes: an update includingnew drugs and 2-drug combinations. Ann Intern Med2011;154:602–613 11. Aroda VR, Edelstein SL, Goldberg RB, et al.; Diabetes PreventionProgram Research Group.Long-term metformin use and vitamin B12defi- ciency in the Diabetes Prevention Program Outcomes Study.J Clin Endocrinol Metab 2016;101: 1754–1761 12. Inzucchi SE, Bergenstal RM, Buse JB, et al. Management ofhyperglycemia in type 2 diabetes, 2015: a patient-centered appro-ach: update to a position statement of the American Diabetes Asso-ciation and the European Association for the Study of Diabetes. Dia-betes Care 2015;38:140–149 13. Chiasson J-L, Josse RG, Hunt JA, et al.The efficacy of acarbose inthe treatment of patients with non-insulin-dependent diabetes mel-litus. A multicenter controlled clinical trial. Ann Intern Med1994;121:928-35. 14. Kahn SE, Haffner SM, Heise MA, et al. Glycemic durability of ro-siglitazone, metformin, or glyburide monotherapy. N Engl J Med2006;355:2427-43. 15. UK Prospective Diabetes Study (UKPDS) Group. Effect of intensi-ve blood-glucose control with metformin on complications in over-weight patients with type 2 diabetes (UKPDS 34). Lancet1998;352:854-65. 16. Fakhoury WK, Lereun C, Wright D. A meta-analysis of placebo-con-trolled clinical trials assessing the efficacy and safety of incretinba-sed medications in patients with type 2 diabetes. Pharmacology2010;86:44-57. 17. Fonseca V, Rosenstock J, Patwardhan R, et al. Effect of metformin androsiglitazone combination therapy in patients with type 2 diabetes mel-litus: a randomized controlled trial. JAMA 2000;283:1695-702 18. Diamant M, Nauck MA, Shaginian R, et al.; 4B Study Group. Glu-cagon-like peptide 1 receptor agonist or bolus insulin with optimi-zed basal insulin in type 2 diabetes. Diabetes Care 2014;37:2763–2773 19. Eng C, Kramer CK, Zinman B, Retnakaran R. Glucagon-like pepti-de-1 receptor agonist and basal insulin combination treatment forthe management of type 2 diabetes: a systematic review and meta-analysis. Lancet 2014;384: 2228–2234 20. Mathieu C, Storms F, Tits J, Veneman TF, Colin IM. Switching frompremixed insulin to basal-bolus insulin glargine plus rapid-actinginsulin: the ATLANTIC study. Acta Clin Belg 2013; 68:28–33 21. Dieuzeide G, Chuang L-M, Almaghamsi A, Zilov A, Chen J-W, La-valle-Gonzalez FJ. Safety ´ and effectiveness of biphasic insulin as-part 30 in people with type 2 diabetes switching from basal-bolus in-sulin regimens in the A1chieve study. Prim Care Diabetes2014;8:111–117 22. Giugliano D, Chiodini P, Maiorino MI, Bellastella G, Esposito K.Intensification of insulin therapy with basal-bolus or premixed in-sulin regimens in type 2 diabetes: a systematic review and meta-analy-sis of randomized controlled trials. Endocrine 2016;51:417–428
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler 1
Yazarlar

Dr. Özge Polat Korkmaz Bu kişi benim

Yayımlanma Tarihi 10 Nisan 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 5 Sayı: 4

Kaynak Göster

APA Polat Korkmaz, D. Ö. (2017). Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması. Klinik Tıp Bilimleri, 5(4), 71-75.
AMA Polat Korkmaz DÖ. Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması. Klinik Tıp Bilimleri. Nisan 2017;5(4):71-75.
Chicago Polat Korkmaz, Dr. Özge. “Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması”. Klinik Tıp Bilimleri 5, sy. 4 (Nisan 2017): 71-75.
EndNote Polat Korkmaz DÖ (01 Nisan 2017) Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması. Klinik Tıp Bilimleri 5 4 71–75.
IEEE D. Ö. Polat Korkmaz, “Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması”, Klinik Tıp Bilimleri, c. 5, sy. 4, ss. 71–75, 2017.
ISNAD Polat Korkmaz, Dr. Özge. “Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması”. Klinik Tıp Bilimleri 5/4 (Nisan 2017), 71-75.
JAMA Polat Korkmaz DÖ. Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması. Klinik Tıp Bilimleri. 2017;5:71–75.
MLA Polat Korkmaz, Dr. Özge. “Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması”. Klinik Tıp Bilimleri, c. 5, sy. 4, 2017, ss. 71-75.
Vancouver Polat Korkmaz DÖ. Tip 2 Diyabette Güncel FarmakolojikTedavi Algoritması. Klinik Tıp Bilimleri. 2017;5(4):71-5.