Tip 1 Diyabet ve Osteoporoz

Yıl 2018, Cilt: 6 Sayı: 4, 10 - 14, 02.04.2018

Doç. Dr. Fatma Ela Keskin

Öz

Öz

Tip 1 Diyabet mellitus (DM) hastalarında uzamış yaşam beklentisi ile kardiyovasküler hastalıklar, osteoporoz ve kognitif bozulmalar gibi yaşa bağlı gelişebilecek komplikasyolar daha çok önem kazanmaya başlamıştır. Tip 1 Dm ve osteoporoz ilişkisi oldukça karmaşık olup bu konuda yapılmış pek çok çalışma bulunmaktadır. Glisemik kontrol ve uzun süreli diyabetin, düşük kemik mineral yoğunluğu (KMD) ve kemik fraktür riski ile ilişkili olduğu bilinmektedir. AyrıcaTip 1 diyabetteki mevcut insulin eksikliğinin kemik yapısının oluşumu üzerinenegatif etkisi olduğu da ileri sürülmüştür. Sonuç olarak tıpkı Tip 2 Dm olduğugibi Tip 1 DM hastalarında da osteoporoz riski normal popülasyondan yüksektir ve tanı koymada gecikme yaşanmaktadır. Bu nedenle yaşam beklentisi uza-mış olan Tip 1 DM’li hasta grubunda bu hastalığın erken tanınıp tedavi edilmesinin önemli bir komorbidite olan fraktür riskinde azalmaya neden olacağı düşünülmektedir.

Anahtar Kelimeler

Tip 1 diyabet, osteoporoz, kırık

Type 1 Diabetes and Osteoporosis

Öz

Abstract

The complications like cardiovascular diseases, osteoporosis and conginif detoriations that are seen in elderly has became more important as the increase oflong life expactance among Type 1 Diabetes mellitus (DM). It is very well known that long duration of diabetes and glisemic control is associated with bone mineral density and bone fragility risk. Also insüline deficiency in Type 1 DM isprovided to be a negative factor on bone stracture. As a result likely in Type 2DM, osteoporosis is more common among Type 1 DM than normal population and diagnosis delates. It is been thougt that the early diagnosis and teratment ofosteoporosis may decrease the risk of fracture which is an important comorbidite, in Type 1 diabetic patients.

Anahtar Kelimeler

Type 1 diabetes mellitus, osteoporosis, fracture

Kaynakça

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