Assessment of central corneal thickness, intraocular pressure and retinal nerve fiber layer thickness at women with polycystic ovary syndrome

Abstract

Objective: To compare intraocular pressure, central cornea thickness, anterior chamber depth, axial length and thickness of retina nerve fiber layer between women with polycystic ovary syndrome and healthy at the same age segment.

Methods: Between August 2015-January 2016, 46 with polycystic ovary syndrome and 53 healthy, were included. After performing refraction measurements, Intraocular pressure, central cornea thickness, anterior chamber depth, axial length and retina nerve fiber layer thickness were investigated. In the statistical analysis of the data, the Independent Samples t test was utilized in the comparison of groups.

Results: While mean age was 23.43±4.52 (16-35) in the group with polycystic ovary syndrome, mean age level was found as 24.09±6.14 (18-41) among the controls (P=0,549). Intraocular pressure values were measured and found as 17.73±2.67 mmHg in the group with polycystic ovary syndrome, while the values were 15.21±2.42 mmHg in the controls (P <0,001). Although it was 79.41±10.28 µm in the group with polycystic ovary syndrome, retina nerve fiber layer thickness in the nasal quadrant was found to be 73.83±10.98 µm among the controls.

Conclusion: We found that the increased levels seen in intraocular pressure and retina nerve fiber layer thickness in the nasal quadrants of the patients with polycystic ovary syndrome were statistically significance. Hence, we recommend that the patients with polycystic ovary syndrome should be closely evaluated as to eye assessment.

Keywords

• Anterior chamber depth,Axial length,Central cornea thickness,Intraocular pressure,Polycystic ovary syndrome

Polikistik over sendromlu kadınlarda santral kornea kalınlığı, göz içi basıncı ve retinal sinir lifi tabakası kalınlığının değerlendirilmesi

Abstract

Amaç: Aynı yaş segmentinde polikistik over sendromlu ve sağlıklı kadınlar arasındaki göz içi basıncı, santral kornea kalınlığı, ön kamara derinliği, aksiyel uzunluk ve retina sinir lifi tabakası kalınlığını karşılaştırmak.

Gereç ve Yöntem : Ağustos 2015-Ocak 2016 tarihleri arasında polikistik over sendromlu 46  ve 53 sağlıklı  kadın dahil edildi. Refraksiyon ölçümleri alındıktan sonra, göziçi basıncı, santral kornea kalınlığı, ön kamara derinliği, aksiyel uzunluk ve retina sinir lifi tabakası kalınlığı incelendi. Verilerin istatistiksel olarak değerlendirilmesinde grupların karşılaştırılması amacıyla Independent Samples t test kullanılmıştır.

Bulgular: Polikistik over sendromlu grupta yaş ortalaması 23.43 ± 4.52 (16-35) iken, kontroller arasında ortalama yaş düzeyi 24.09 ± 6.14 (18.54) olarak bulundu (p = 0,549). Polikistik over sendromlu grupta göz içi basıncı değerleri 17.73 ± 2.67 mmHg, kontrollerde 15.21 ± 2.42 mmHg bulundu (P <0,001). Nazal kadrandaki retina sinir lifi kalınlığı polikistik over sendromlu grupta 79,41±10,28 mikron iken kontrol grubunda 73,83±10,98 mikron olduğu bulundu (P <0,001).

Sonuç: Polikistik over sendromlu hastaların nazal kadrandaki retina sinir lifi tabakası kalınlığı ve  göz içi basıncında görülen artmış düzeylerin istatistiksel olarak anlamlı olduğu bulduk. Bu nedenle, polikistik over sendromlu hastaların göz muayenesi açısından yakından değerlendirilmesini önerilmekteyiz.

Keywords

• Ön kamara derinliği,aksiyel uzunluk,santral kornea kalınlığı,göz içi basıncı,polikistik over sendromu,retina sinir lifi tabakası kalınlığı

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