Endocrinologic Complications in Patients With Transfusion Dependent Thalassemia

Abstract

Abstract

The survival of the patients with transfusion-induced thalassemia has improvedwith the development of treatment options. However, iron overload in various organs continues to reduce the quality of life. Cardiac toxicity is still the leading cause of death and endocrine complications are the major cause of morbidity. Therefore, the importance of diagnosis and treatment of endocrine complications has increased in order to increase the quality of life of patients. The most common endocrine complications in patients are hypogonadism, diabetes, short stature, hypothyroidism and hypoparathyroidism.

Keywords

• Transfusion dependent thalas-semia,endocrinologic com-plications.

Transfüzyon Bağımlı Talasemi Hastalarında Görülen Endokrin Komplikasyonlar

Öz

Öz

Transfüzyona bağımlı talasemi hastalarında tedavi olanaklarının gelişmesi ile hastaların yaşam süreleri uzamıştır. Ancak çeşitli organlarda aşırı demir yükü yaşam kalitesini düşürmeye devam etmektedir. Kardiyak toksisite halen başlıca ölüm nedeni olup endokrin komplikasyonlar başlıca morbidite nedenidir. Bu nedenle hastaların yaşam kalitelerinin artması için endokrin komplikasyonlarının tanı ve tedavisinin önemi daha da artmıştır. Hastalarda sık görülen endokrin komplikasyonlar hipogonadizm, diyabet, boy kısalığı, osteoporoz gibi kemik hastalıkları, hipotiroidizm ve hipoparatiroidizmdir.

Anahtar Kelimeler

• Transfüzyon bağımlı talasemi,endokrinolojik komplikasyonlar

Kaynakça

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