Periodic Fever Syndromes

Abstract

Abstract

The periodic syndromes represent a heterogeneous group of disorders that can be very difficult for practicing physicians to diagnosis and treat. This article presents an orderly approach to hyperimmunoglobulin D syndrome; tumor necrosis factor receptor-1 periodic syndrome; periodic fever with aphthous stomatitis, pharyngitis, and adenitis syndrome; and cryopyrin-associated periodic syndromes and others by highlighting the disease presentation, diagnosis, pathogenesis, and treatment.

Keywords

• Pediodic fever,hyperimmunoglobulin D,PFAPAsyndrome

Periyodik Ateş Sendromları

Öz

Öz

Periyodik ateş sendromları tanı ve tedavi açısından hekimleri zorlayan heterojen bir grup hastalıkları tanımlamak için kullanılan bir deyimdir. Bu yazıda hiperimmünglobülin D sendromu, tümör nekroz faktör reseptör-1 periyodik sendromu, periyodik ateş, aftöz stomatit, farenjit ve adenit sendromu ve Kriyoprin-ilişkili periyodik sendromları ve diğerleri, klinik, tanı, patogenez ve tedavi yaklaşımları açısından kısaca gözden geçirilmektedir.

Anahtar Kelimeler

• Periyodik ateş,hiperimmünglobülin D,PFAPA sendromu

Kaynakça

1. Kaynaklar 1.Burton MJ, Pollard AJ, Ramsden JD. Tonsillectomy for perio-dic fever, aphthous stomatitis, pharyngitis and cervical ade-nitis syndrome (PFAPA). Cochrane Database of Systematic Re-views 2010, Issue 9. Art. No.: CD008669. 2.Frenkel J, Houten SM, Waterham HR, et al. Clinical and mo-lecular variability in childhood periodic fever with hyperim-munoglobulinemia D. Rheumatology 2001; 40: 579-84. 3.Gedalia A. Hereditary Periodic Fever Syndromes. In: Klieg-man RM, Jenson HB, Behrman RE, Stanton BF, eds. NelsonTextbook of Pediatrics, 19th ed. Philadelphia: Saunders Els-evier 2011: 855-860.e1. 4.Goldbach-Mansky R, Dailey NJ, Canna SW, et al. Neonatal-onset multisystem inflammatory disease responsive to inter-leukin-1β inhibition. N Eng J Med 2006; 355: 581-92.5.Grateau G. Clinical and genetic aspects of hereditary perio-dic fever syndromes. Rheumatology 2004; 43: 410-5. 6.Hawkins PN, Lachmann HJ, Aganna E, et al. Spectrum of cli-nical features in Muckle-Wells syndrome and response to ana-kinra. Arthritis Rheum 2004; 50: 607-12. 7.Horwitz M, Benson KF, Person RE, Aprikyan AG, Dale DC.Neutrophil elastase mutations define a 21-day biological clockin cyclic hematopoiesis. Nat Gen 1999; 23: 433-6. 8.Hull KM, Drewe E, Aksentijevich I, et al. The TNF receptor-associated periodic syndrome (TRAPS): Emerging conceptsof an autoinflammatory disorder. Medicine 2002; 81: 349-68. 9.Lierl M. Periodic fever syndromes: a diagnostic challenge forthe allergist. Allergy 2007; 62: 1349-58. 10.Long SS, Edwards KM. Prolonged, recurrent, and periodic fe-ver syndromes: In: Long SS, Pickering LK, Grober CG, eds.Principles and Practice of Pediatric Infectious Diseases, 4thed. Edinburgh: Elsevier Saunders 2012: 117-27.e4. 11.Marcuzzi A, Piscianz E, Kleiner G, et al. Clinical genetic tes-ting of periodic fever syndromes. BioMed Research Interna-tional 2013; Article ID 501305; 1-8. 12.Muckle TJ, Wells M. Urticaria, deafness and amiloidosis: anew heredo-familial syndrome. QJM 1962; 31: 235. 13.Wurster VM, Carlucci JG, Feder HM, Edwards KM. Long-termfollow-up of children with periodic fever, aphthous stomati-tis, pharyngitis and cervical adenitis syndrome. J Pediatr 2011;159: 958-64.