INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS

Selcan Çil; Mehmet Çağrı Karakurum

doi:10.24998/maeusabed.1892924

TR EN

PARVOVİRAL GASTROENTERİTİSLİ KÖPEKLERDE SERUM D VİTAMİNİ DÜZEYLERİ ARAŞTIRILMASI

Abstract

İnsan ve hayvan sağlığı konusunda son yıllarda oldukça popüler olan D vitamini pek çok hastalıkla ilişkilendirilmiş fakat köpek nüfusunda ciddi kayıplara sebep olan, mortalite ve bulaşma yüzdesi yüksek olan Parvoviral Gastroenteritis ile enfekte köpeklerde vitamin ile ilişkilendirilen yeterince çalışmaya rastlanmamıştır. Bu çalışmada Parvoviral Gastroenteritli köpeklerde 25 hidroksi vitamin D3 düzeylerinin ölçülmesi ve vitaminin hastalık üzerindeki etkileri hakkında bilgi sahibi olunması amaçlandı. Çalışmada “I. Parvoviral Gastroenteritli Köpekler” ve “II. Sağlıklı Köpekler” olmak üzere iki grup incelendi. Araştırmada canine parvovirus tip 2 (CPV- 2) pozitif olan, 0-12 aylık, farklı cinsiyet ve ırka sahip öncesinde herhangi bir aşılama yapılmamış bir grup köpek ile 0-12 aylık, farklı cinsiyet ve ırka sahip hastalık belirtisi göstermeyen sağlıklı bir grup köpekten kan örneği alınmıştır. Araştırmaya dâhil edilen köpeklerin her birinin Vena cephalica antebrachii’sinden antikoagülansız serum tüplerine 2 ml kan örneği alınarak santrifüje tabi tutulmuş, ardından radyoimmünoassay yöntemi ile bu örneklerdeki 25 hidroksi vitamin D3 düzeyleri belirlenmiştir. Yapılan bu tez çalışmasında ise CPV ile enfekte köpekler ile sağlıklı köpekler arasındaki serum 25(OH)D3 seviyeleri arasındaki fark istatiksel olarak anlamlı bulunmasa da D vitamini metabolitlerinin bilinen immunmodülatör etkileri göz önüne alındığında Parvoviral Gastroenterit ile olası düşük D vitamini seviyeleri arasında ilişki mümkündür.

Keywords

Supporting Institution

Burdur Mehmet Akif Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü

Project Number

0789-YL-21

Ethical Statement

Bu araştırma, Burdur Mehmet Akif Ersoy Üniversitesi Hayvan Deneyleri Yerel Etik Kurulu (MAKÜ-HADYEK) tarafından 17.11.2021 tarihinde verilen 831 sayılı etik kurul onayı ile yürütülmüştür.

INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS

Abstract

Vitamin D has been very popular in human and animal health in recent years. It has been associated with many diseases, but there have not been enough studies on the vitamin in dogs infected with Parvoviral Gastroenteritis, which causes serious losses in the dog population, high mortality, and high transmission rates. In this study, the aim was to measure 25-hydroxyvitamin D3 levels in dogs with Parvoviral Gastroenteritis and to gather information on the effects of vitamin D3 on the disease. In the study, two groups, “I. Dogs with Parvoviral Gastroenteritis” and “II. Healthy Dogs,” were examined. In the study, blood was obtained from a group of 0-12 months old dogs of different sexes and breeds who were positive for canine parvovirus type 2 (CPV-2) that had not been vaccinated before, and a healthy group of dogs 0-12 months of age, of different sexes and breeds, who did not show any signs of disease, sample was taken. 2 ml blood samples were taken from Vena cephalica antebrachii of each of the dogs included in the study into serum tubes without anticoagulant and centrifuged, then 25 hydroxy vitamin D3 levels in these samples were determined by radioimmunoassay method. In this study, although the difference in serum 25(OH)D3 levels between CPV-infected dogs and healthy dogs was not statistically significant, a relationship between Parvoviral Gastroenteritis and possible low vitamin D levels is plausible, given vitamin D metabolites' known immunomodulatory effects.

Keywords

Supporting Institution

Burdur Mehmet Akif University's Scientific Research Projects Coordination Unit

Project Number

0789-YL-21

Ethical Statement

This study was conducted after the approval of the Burdur Mehmet Akif Ersoy University Animal Experiments Local Ethics Committee (MAKÜ-HADYEK-17.11.2021 and No: 831).

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Details

Primary Language

English

Subjects

Veterinary Medicine

Journal Section

Research Article

Authors

Selcan Çil
0009-0004-4542-6352
Türkiye

Mehmet Çağrı Karakurum ^*
0000-0002-0767-883X
Türkiye

Publication Date

April 27, 2026

Submission Date

February 19, 2026

Acceptance Date

March 25, 2026

Published in Issue

Year 2026 Number: 2026

DOI

https://doi.org/10.24998/maeusabed.1892924

IZ

https://izlik.org/JA24EG32ED

Cite

RIS / Bibtex

APA

Çil, S., & Karakurum, M. Ç. (2026). INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS. Mehmet Akif Ersoy University Journal of Health Sciences Institute, 2026. https://doi.org/10.24998/maeusabed.1892924

AMA

1.Çil S, Karakurum MÇ. INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2026;(2026). doi:10.24998/maeusabed.1892924

Chicago

Çil, Selcan, and Mehmet Çağrı Karakurum. 2026. “INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS”. Mehmet Akif Ersoy University Journal of Health Sciences Institute, nos. 2026. https://doi.org/10.24998/maeusabed.1892924.

EndNote

Çil S, Karakurum MÇ (April 1, 2026) INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS. Mehmet Akif Ersoy University Journal of Health Sciences Institute 2026

IEEE

[1]S. Çil and M. Ç. Karakurum, “INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS”, Mehmet Akif Ersoy University Journal of Health Sciences Institute, no. 2026, Apr. 2026, doi: 10.24998/maeusabed.1892924.

ISNAD

Çil, Selcan - Karakurum, Mehmet Çağrı. “INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS”. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2026 (April 1, 2026). https://doi.org/10.24998/maeusabed.1892924.

JAMA

1.Çil S, Karakurum MÇ. INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2026. doi:10.24998/maeusabed.1892924.

MLA

Çil, Selcan, and Mehmet Çağrı Karakurum. “INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS”. Mehmet Akif Ersoy University Journal of Health Sciences Institute, no. 2026, Apr. 2026, doi:10.24998/maeusabed.1892924.

Vancouver

1.Selcan Çil, Mehmet Çağrı Karakurum. INVESTIGATION OF SERUM VITAMIN D LEVELS IN DOGS WITH PARVOVIRAL GASTROENTERITIS. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2026 Apr. 1;(2026). doi:10.24998/maeusabed.1892924

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