A FAMILIAL COELIAC DISEASE FROM TURKEY

Yıl 1999, Cilt: 12 Sayı: 2, 91 - 93, 03.12.2016

Gülbin Aygencel Rıza Soylu Figen Batman

Öz

A Turkish grandmother, her son and grandson all complaining of diarrhoea were diagnosed as suffering from Coeliac disease on the basis of clinical symptoms, antigliadin antibodies and duodenal biopsy. HLA antigens were also studied on patients to provide the information about relationship between these antigens and Coeliac disease. Therefore we confirm that HLA DR3 and DR7 negative patients who usually DQ2 negative, are DR4 positive may also be true for Turkish patients with Coeliac disease.
Key Words: Coeliac Disease, Familial, In Turkey.

Kaynakça

• /. Afeiiwisse GW. Diagnostic criteria in Coeliac disease. Acta Pediatr Scand 1970/59:461-464.
• Ascher tl, tirantz I, Kristiansson B. Increasing incidence of Coeliac disease in Sweden. Arch Dis Child 1991;66:608-611.
• Catassi C, Ratsch in, Fabiani E, et at Coeliac disease in the year 2000: exploring the iceberg. Lancet 1994;343:200-203.
• Maki FI, Collin P. Coeliac disease. Lancet 1997;349:1755-1759.
• Collin P, Flaki Ft. Associated disorders in Coeliac disease; clinical aspects. Scand J Gastroenterol 1994;29:769-775.
• Ferguson A, Arranz E, O'Flahony S. Clinical and pathological spectrum of Coeliac disease active, silent, latent, potential. Gut 1993;34:150-151.
• flolmes GTK, Prior P, Lane Mr, et at. Malignancy in Coeliac disease-effect of gluten free diet. Gut 1989;30:333-338.
• Ladinser B, Rossipal E, Pittschieler K. Endomysium antibodies in Coeliac disease; an improved method. Gut 1994;35:776-778.
• Sollid LM, Thorsby E. HLA susceptibility genes in Coeliac disease: genetic mapping and role in pathogenesis. Gastroenterology 1993; 105:910- 922.
• Ferguson A. Hew perspectives of the pathogenesis of Coeliac disease: evolution of a working clinical definition. J Intern Med 1996;240:315-318.