The aim of the Mathematical Sciences and Applications E-Notes is to disseminate mathematical knowledge, promote mathematical thinking, highlight the importance of mathematical applications in various fields, publish original and innovative research in mathematics and related disciplines, and bridge the gap between theoretical mathematical concepts and their practical implementation.

The journal focuses on original research in various areas, including the development of mathematical theories, the application of mathematical methods, mathematical modeling, and problem-solving within the realm of mathematics. This scope includes pure mathematics, applied mathematics, statistics, probability theory, mathematical physics, mathematical biology, mathematical economics, mathematical engineering, and other related disciplines.

The articles within the journal cover diverse topics such as the development and analysis of mathematical theories, the introduction of new mathematical techniques, the use of mathematical modeling and simulations, algorithms for solving mathematical problems, mathematical optimization methods, and mathematical statistical analyses. Additionally, the journal highlights the importance of mathematical knowledge in different applied domains and features studies on the application of mathematical approaches in industries, engineering, sciences, and other disciplines.