Comparison Of The Efficiency Of Dexamethasone And Droperidole In The Prevention Of Postoperative Nausea And Vomiting

Year 2003, Volume: 4 Issue: 3, 17 - 20, 17.09.2003

İrfan Güngör Nedim Çekmen Mehmet Akçabay Mustafa Arslan

Abstract

Objective:We compared the antiemetic effect of dexametasone with droperidole in patients who hadunderwent laparascopic cholecystetomy.Materials ve methods:40 patients were randomly divided into two groups with 20 patients in each group. GroupDHBP (Droperidole), received 1.25 mg droperidole IV and Group D (Dexamethasone), received 5 mgdexamethasone IV ten minutes before extubation.Results:Nausea-vomiting score was not statistically different between the study groups.The incidence of nauseain group D was found to be more frequent in comparison to group DHBP within a 24 hour period although this wasnot statistically significant. Additional antiemetic requirement was more in Group D compared to Group DHBPand this was not statistically significant. There was no difference in analgesic requirement and side effectsbetween the study groups.Conclusions:Our study has shown that 5 mg dexamethasone can be used to prevent PONV

Keywords

Postoperative nausea and vomiting (PONV), dexamethasone, droperidole

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