VİTAMİN D KANSERDEN SORUMLU MU? DOES VITAMIN D CAUSE TO CANCER?

Yıl 2014, Cilt: 1 Sayı: 1, 34 - 47, 16.12.2014

Sevil Uygun İlikhan Fatih Kuzu , Muammer Bilici , Taner Bayraktaroğlu

Öz

 Özet

Vitamin D, kemik metabolizması haricinde birçok hastalık ve kansere karşı potansiyel koruyucu etkileri vardır. Hücre proliferasyonu, apopitozu, inflamasyon ve angiogenez üzerinden kanser insidansı, progresyonu ve bazı kanser tiplerinde mortaliteye karşı vitamin D’nin koruyucu etiklerine ait veriler giderek artmaktadır. Meme kanseri, prostat kanseri, gastrointestinal kanserler açısından  epidemiyolojik veriler ve preklinik bulgular Vitamin D’nin kanser gelişimi ve progresyonundaki rollerini desteklemektedir. 

Anahtar kelimeler: Vitamin D, kanser, dehidrokolekalsiferol

 DOES VITAMIN D CAUSE TO CANCER?

Vitamin D has a potential protective effects against cancer and some diseases except bone metabolism. Data  about the protective  effects of  vitamin D against cancer incidence, progression and mortality of different types  which are due to cell proliferatiton, apaptozis, inflammation and angiogenesis, have increased. The epidemiologycal data and preclinical findings support the role of vitamin D at cancer development and progression in relation to breast, prostat and colorectal cancers.

Key words:Vitamin D, cancer, dehidrocolecalsiferol

Anahtar Kelimeler

Vitamin D, kanser, dehidrokolekalsiferol

Kaynakça

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