Klinik Araştırma

Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19

Cilt: 5 Sayı: 1 15 Ocak 2023
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Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19

Öz

Aim: The ATRIA score was developed to assess the probability of an ischemic stroke in patients with atrial fibrillation (AF). The modified ATRIA (M-ATRIA) risk score incorporates predictive risk variables for coronavirus disease 2019 (COVID-19). As a result, we looked into the association between the M-ATRIA risk score and the risk of in-hospital death in COVID-19 patients.
Materials and Methods: The data of 595 inpatients in the COVID-19 research were evaluated retrospectively and separated into three groups based on the M-ATRIA scoring system. The M-ATRIA score used the troponin I level as a parameter in place of the proteinuria criterion in the ATRIA score. Those with a score between 0 and 5 were classified as group 1 (n = 269), those with a score of 6 as group 2 (n = 64), and those with a score of 7 and above were classified as group 3 (n = 162). In-hospital death, mechanical ventilation, and admission to the critical-care unit were all considered adverse clinical events.
Results: The M-ATRIA risk score associated with adverse clinical events (all, p < 0.001). An M-ATRIA score of 6, an M-ATRIA score greater than 7, procalcitonin, and C- reactive protein were found to be independent predictors of in-hospital mortality in the multivariate logistic regression analysis. In the ROC analysis, an M-ATRIA score of 4.5 or above predicted in-hospital mortality with a sensitivity of 90.2% and a specificity of 58.9%.
Conclusion: Regardless of the status of AF, the M-ATRIA risk score computed at admission may be a valuable tool for predicting in-hospital mortality in COVID-19 patients.

Anahtar Kelimeler

Kaynakça

  1. 1. Xu S, Huang R, Sy LS, et al. COVID-19 Vaccination and Non-COVID-19 Mortality Risk - Seven Integrated Health Care Organizations, United States, December 14, 2020-July 31, 2021. MMWR Morb Mortal Wkly Rep. 2021;70:1520-24.
  2. 2. Godoy LC, Goligher EC, Lawler PR, et al. Anticipating and managing coagulopathy and thrombotic manifestations of severe COVID-19. CMAJ. 2020;192:E1156-61.
  3. 3. Singer DE, Chang Y, Borowsky LH, et al. A new risk scheme to predict ischemic stroke and other thromboembolism in atrial fibrillation: the ATRIA study stroke risk score. J Am Heart Assoc. 2013;2:e000250.
  4. 4. Van Den Ham HA, Klungel OH, Singer DE, et al. Comparative performance of ATRIA, CHADS2, and CHA2DS2-VASc risk scores predicting stroke Comparison of the ATRIA, CHADS2, and CHA2DS2-VASc stroke risk scores 3209in patients with atrial fibrillation in a national primary care database and the impact on treatment decisions. J Am Coll Cardiol. 2015;66:1851-9.
  5. 5. Cetinkal G, Kocas BB, Ser OS, et al. Assessment of the Modified CHA2DS2VASc Risk Score in Predicting Mortality in Patients Hospitalized With COVID-19. Am J Cardiol. 2020;135:143-9.
  6. 6. Quisi A, Alıcı G, Harbalıoğlu H, et al. The CHA2DS2-VASc score and in-hospital mortality in patients with COVID-19: A multicenter retrospective cohort study. Turk Kardiyol Dern Ars. 2020;48:656-63.
  7. 7. Al Abbasi B, Torres P, Ramos-Tuarez F, et al. Cardiac Troponin-I and COVID-19: A Prognostic Tool for In-Hospital Mortality. Cardiol Res. 2020;11:398-404.
  8. 8. The Republic of Turkey Ministry of Health. COVID-19 (SARS-CoV-2 Infection) (Study of Scientific Board) General Information, Epidemiology and Diagnosis.2020. Website https://covid19.saglik.gov.tr/Eklenti/39061/0/covid-19rehberieriskinhastatedavisipdf.pdf accessed date 9 November 2020

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri

Bölüm

Klinik Araştırma

Yayımlanma Tarihi

15 Ocak 2023

Gönderilme Tarihi

16 Eylül 2022

Kabul Tarihi

25 Ekim 2022

Yayımlandığı Sayı

Yıl 2023 Cilt: 5 Sayı: 1

Kaynak Göster

APA
Afşin, A., Turgut, K., Bursa, N., Yavuz, E., Güven, T., & Hoşoğlu, Y. (2023). Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19. Medical Records, 5(1), 107-14. https://doi.org/10.37990/medr.1176092
AMA
1.Afşin A, Turgut K, Bursa N, Yavuz E, Güven T, Hoşoğlu Y. Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19. Med Records. 2023;5(1):107-14. doi:10.37990/medr.1176092
Chicago
Afşin, Abdulmecit, Kasım Turgut, Nurbanu Bursa, Erdal Yavuz, Taner Güven, ve Yusuf Hoşoğlu. 2023. “Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19”. Medical Records 5 (1): 107-14. https://doi.org/10.37990/medr.1176092.
EndNote
Afşin A, Turgut K, Bursa N, Yavuz E, Güven T, Hoşoğlu Y (01 Ocak 2023) Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19. Medical Records 5 1 107–14.
IEEE
[1]A. Afşin, K. Turgut, N. Bursa, E. Yavuz, T. Güven, ve Y. Hoşoğlu, “Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19”, Med Records, c. 5, sy 1, ss. 107–14, Oca. 2023, doi: 10.37990/medr.1176092.
ISNAD
Afşin, Abdulmecit - Turgut, Kasım - Bursa, Nurbanu - Yavuz, Erdal - Güven, Taner - Hoşoğlu, Yusuf. “Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19”. Medical Records 5/1 (01 Ocak 2023): 107-14. https://doi.org/10.37990/medr.1176092.
JAMA
1.Afşin A, Turgut K, Bursa N, Yavuz E, Güven T, Hoşoğlu Y. Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19. Med Records. 2023;5:107–14.
MLA
Afşin, Abdulmecit, vd. “Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19”. Medical Records, c. 5, sy 1, Ocak 2023, ss. 107-14, doi:10.37990/medr.1176092.
Vancouver
1.Abdulmecit Afşin, Kasım Turgut, Nurbanu Bursa, Erdal Yavuz, Taner Güven, Yusuf Hoşoğlu. Evaluation of Relationship between Modified ATRIA Risk Score and Mortality in Hospitalized Patients with COVID-19. Med Records. 01 Ocak 2023;5(1):107-14. doi:10.37990/medr.1176092