Implications of Gastric Diverticulum in the Incidence of Metaplasia: An Analysis of 37 Cases

Abstract

Aim: The present study aimed to investigate the potential association between gastric fundus diverticulum and metaplasia by retrospectively analysing patient data and biopsy results. Material and Methods: 37 patients with gastric fundus diverticulum were examined, with their data compared to a control group of 50 patients without it. All diagnoses were made endoscopically. Demographic information, laboratory parameters, and endoscopic biopsy results were compared between the groups. Results: No significant differences were identified between the two groups concerning several laboratory parameters. However, there were significant differences in lymphocytes, urea, albumin, Na, and K values (p<0.05). Helicobacter pylori and atrophy distributions did not differ between the groups (p>0.05), while a notable difference was seen in the distribution of metaplasia (p<0.05). Metaplasia positivity was found to be 16% in patients without gastric diverticulum and 43.2% in patients with gastric diverticulum. Conclusions: This study found a higher prevalence of metaplasia positivity in patients with gastric diverticulum than those without. These findings suggest a potentially significant link between the gastric diverticulum and the occurrence of metaplasia, which warrants further research to better understand the underlying mechanisms and implications for patient management.

Keywords

• gastric diverticula
• metaplasia
• gastric biopsy
• endoscopy
• gastroenterology

Kaynakça

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