Cancer Data, Case Increase Rates and Future Prospects in the Northeastern Anatolia Region of Türkiye, a Special Region for Gastric and Esophageal Cancers in 2018-2023

Yıl 2025, Cilt: 7 Sayı: 1, 258 - 262, 15.01.2025

Alperen Akansel Çağlar , Aykut Turhan , Pınar Çoban Eşdur , Yasin Emrah Soylu , Mehmet Bilici , Salim Başol Tekin

https://doi.org/10.37990/medr.1572275

Öz

Aim: Cancer is a major cause of death. Globocan data shows 20 million new cancer cases and 9.7 million cancer deaths a year. Lung cancer is the most common cancer globally, followed by breast, colorectal, prostate and stomach cancers. Cancer types vary by age, gender, race, and region. Documenting regional cancer data is crucial for screening, early diagnosis, and treatment of common cancers, as well as understanding the underlying causes. Despite the high incidence of upper gastrointestinal (GI) cancers in eastern Türkiye, there is little documented evidence on specific cancer types in these regions.
Material and Method: In order to investigate the incidence of cancer in our region, the medical records of 6,603 patients diagnosed with cancer and subsequently treated in our clinic between 2018 and 2023 were analysed and specific cancer sites were recorded.
Results: It has been demonstrated that cancers of the upper GI tract, represent the most prevalent cancer site, accounting for 21.2% (n=1403) of all cases. This equates to one in every five patients diagnosed with cancer. Additionally, significant findings were yielded with respect to other forms of cancer.
Conclusion: It is imperative to document these data to highlight the necessity for investigating and preventing the underlying causes of upper GI cancer in our region. Furthermore, the establishment of screening programs for early diagnosis and intensified research on treatment modalities are crucial steps in combating this disease.

Anahtar Kelimeler

Cancer data in Northeast Anatolia , stomach and oesophageal cancer in Northeast Anatolia , Asian belt

Etik Beyan

Ethics committee approval dated 27.09.2024 and numbered B.30.2.ATA.0.01.00/538 was obtained for our study

Kaynakça

• Bray F, Laversanne M, Weiderpass E, Soerjomataram I. The ever-increasing importance of cancer as a leading cause of premature death worldwide. Cancer. 2021;127:3029-30.
• Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74:229-63.
• Bray F, Parkin DM; African Cancer Registry Network. Cancer in sub-Saharan Africa in 2020: a review of current estimates of the national burden, data gaps, and future needs. Lancet Oncol. 2022;23:719-28.
• Elezoğlu B, Dellal FD. Cancer cases during five year period in the secondary health care institution of East Anatolia Region. Okmeydanı Tıp Dergisi. 2015;31:18-21.
• Tuncer İ, Uygan İ, Kösem M, et al. Van ve çevresinde görülen üst gastrointestinal sistem kanserlerinin demografik ve histopatolojik özellikleri. Van Tıp Dergisi. 2001;8:10-3.
• Machlowska J, Baj J, Sitarz M, et al. Gastric cancer: epidemiology, risk factors, classification, genomic characteristics and treatment strategies. Int J Mol Sci. 2020;21:4012.
• Ang TL, Fock KM. Clinical epidemiology of gastric cancer. Singapore Med J. 2014;55:621-8.
• Lauwers GY, Mullen JT, Schreiber KEC, Chung DC. Familial gastric cancers: a review with focus on hereditary diffuse gastric cancer syndrome. Pathology Case Reviews. 2014;19:66-73.
• Kim J, Cho YA, Choi WJ, Jeong SH. Gene-diet interactions in gastric cancer risk: a systematic review. World J Gastroenterol. 2014;20:9600-10.
• López MJ, Carbajal J, Alfaro AL, et al. Characteristics of gastric cancer around the world. Crit Rev Oncol Hematol. 2023;181:103841.
• Çiftel S, Okçu N, Dursun H, et al. Helicobacter pylori prevalance in our region. akademik gastroenteroloji dergisi, 2016;15;1-4.
• Lander S, Lander E, Gibson MK. Esophageal cancer: overview, risk factors, and reasons for the rise. Curr Gastroenterol Rep. 2023;25:275-9.
• Prabhu A, Obi KO, Rubenstein JH. The synergistic effects of alcohol and tobacco consumption on the risk of esophageal squamous cell carcinoma: a meta-analysis. Am J Gastroenterol. 2014;109:822-7.
• Islami F, Poustchi H, Pourshams A, et al. A prospective study of tea drinking temperature and risk of esophageal squamous cell carcinoma. Int J Cancer. 2020;146:18-25.
• Keeney S, Bauer TL. Epidemiology of adenocarcinoma of the esophagogastric junction. Surg Oncol Clin N Am. 2006;15:687-96.
• Morgan E, Soerjomataram I, Rumgay H, et al. The global landscape of esophageal squamous cell carcinoma and esophageal adenocarcinoma incidence and mortality in 2020 and projections to 2040: new estimates from GLOBOCAN 2020. Gastroenterology. 2022;163:649-658.e2.