The Impact of Thoracic CT Findings, Adiposity Parameters, and Laboratory Data on COVID-19 Prognosis

Öz

Aim: Numerous studies have been conducted concerning the clinical, laboratory, and radiological methods and markers to predict the prognosis of Coronavirus disease 2019 (COVID-19). In this study, we aim to explore the impact of COVID-19 severity scores, adiposity parameters, and laboratory findings on the prognosis of COVID-19. Material and Method: A retrospective study was performed with 98 patients who were both computed tomography (CT) and polymerase chain reaction positive. Clinical outcomes, laboratory findings, thorax CT findings, and adiposity parameters (such as hepatic steatosis and visceral fat amount) obtained from thorax CTs were evaluated. Results: The frequency of hepatic steatosis, lung severity score, and C-reactive protein (CRP) levels were higher, whereas lymphocyte count was lower in hospitalized patients than in patients treated at home. Among hospitalized patients, in addition to previous laboratory and radiological findings d-dimer and ferritin levels were higher in patients requiring intensive care. Among patients admitted to intensive care unit (ICU), the visceral to subcutaneous adipose tissue ratio was higher in patients who died than in patients who survived; none of the other parameters showed a significant difference. Conclusion: COVID-19 CT score, adiposity parameters, and laboratory results were related to the prognosis of COVID-19. These results align with those of other recent research. A formula based on patient age, CT score, and CRP levels can be employed to determine if the patient requires hospital admission.

Anahtar Kelimeler

• COVID-19
• quantitative evaluation
• tomography
• visceral adipose tissue
• subcutaneous adipose tissue

Etik Beyan

The study received approval from Karamanoğlu Mehmetbey University's Institutional Ethics and Research Committee (approval number: 10-2022/07, approval date: 08.11.2022).

Kaynakça

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