Klinik Araştırma

Effects of Stroke Severity on Treatment Initiated in the Emergency Department

Cilt: 7 Sayı: 2 9 Mayıs 2025
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Effects of Stroke Severity on Treatment Initiated in the Emergency Department

Öz

Aim: Stroke severity depends on the treatments administered from the moment the patient enters the emergency department and the success of patient management. In our study, we aimed to evaluate the effect of National Institutes of Health Stroke Scale (NIHSS) scoring on intervention time and the relationship of qualitative measures with clinical outcome in patients in our stroke center. Material and Method: The files of patients who underwent iv TPA and/or mechanical thrombectomy in the emergency department who were followed up at the stroke center between 2022 and 2023 were retrospectively reviewed. Patients were divided into 4 groups as NIHSS score 0-5, 5-10, 10-20, ≥21; 3 groups as modified Rankin Scale (MRS) score 0-2, 3-5 and 6. Mean, standard deviation, median minimum, maximum, frequency and ratio values were used in the descriptive statistics of the data. ANOVA (Tukey test), Kruskal-Wallis, Mann-Whitney u test were used in the analysis of quantitative independent data; chi-square test was used in the analysis of qualitative independent data, and fischer test was used when chi-square test conditions were not met. Results: Symptom puncture, symptom recanalization, puncture recanalization, door imaging, door TPA, door puncture times did not differ significantly (p>0.05) between stroke severity groups. The first-pass recanalization rate was significantly (p<0.05) higher in the MRS III-IV-V group than in the MRS 0-I-II group, while the first-pass recanalization rate did not differ significantly (p>0.05) between the MRS VI group and the MRS 0-I-II, MRS III-IV-V groups. In the group with bleeding at 24 hours, TICI stage was significantly (p<0.05) lower, 3rd month MRS score was significantly (p<0.05) higher, and tan score was significantly (p<0.05) lower than the group without bleeding at 24 hours. Conclusion: Although there is no correlation between stroke severity and emergency department quality-metrics times, recanalization success has an effect on good outcome. Instroke, the coordination and experience of all components of the neurology and emergency medicine clinics hould be good in terms of diagnosis and timing.

Anahtar Kelimeler

Etik Beyan

This study received approval from the Clinical Studies Ethics Committee of University of Health Sciences Haseki Training And Research Hospital (Decision No: 261-2023) and was conducted in accordance with the ethical standards outlined in the Declaration of Helsinki.

Kaynakça

  1. Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2095-2128. Erratum in: Lancet. 2013;381:628.
  2. Berkhemer OA, Fransen PS, Beumer D, et al. A randomized trial of intra-arterial treatment for acute ischemic stroke. N Engl J Med. 2015;372:11-20. Erratum in: N Engl J Med. 2015;372:94.
  3. Saver JL, Goyal M, Bonafe A, et al. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015;372:2285-95.
  4. Jovin TG, Chamorro A, Cobo E, et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015;372:2296-306.
  5. Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2019;50:e344-418. Erratum in: Stroke. 2019;50:e440-1.
  6. Albers GW, Marks MP, Kemp S, et al. Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N Engl J Med. 2018;378:708-18.
  7. Nogueira RG, Jadhav AP, Haussen DC, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med. 2018;378:11-21.
  8. T.C. Sağlık Bakanlığı Sağlık Hizmetleri Genel Müdürlüğü Araştırma, Geliştirme ve Sağlık Teknolojisi Değerlendirme Dairesi Başkanlığı. Akut İskemik İnme Tanı ve Tedavi Rehberi, Version 1.0. Ankara: Çankaya. Republic of Turkey Ministry of Health. 2020;14-43.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Nöroloji ve Nöromüsküler Hastalıklar

Bölüm

Klinik Araştırma

Yayımlanma Tarihi

9 Mayıs 2025

Gönderilme Tarihi

31 Ocak 2025

Kabul Tarihi

11 Nisan 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 7 Sayı: 2

Kaynak Göster

APA
Memiş, Z., Kuru, İ., Gök, S., İncirci, B., Topcu, A., Ergenç, H., & Çokar, A. Ö. (2025). Effects of Stroke Severity on Treatment Initiated in the Emergency Department. Medical Records, 7(2), 354-360. https://doi.org/10.37990/medr.1620713
AMA
1.Memiş Z, Kuru İ, Gök S, vd. Effects of Stroke Severity on Treatment Initiated in the Emergency Department. Med Records. 2025;7(2):354-360. doi:10.37990/medr.1620713
Chicago
Memiş, Zülfikar, İrem Kuru, Sinem Gök, vd. 2025. “Effects of Stroke Severity on Treatment Initiated in the Emergency Department”. Medical Records 7 (2): 354-60. https://doi.org/10.37990/medr.1620713.
EndNote
Memiş Z, Kuru İ, Gök S, İncirci B, Topcu A, Ergenç H, Çokar AÖ (01 Mayıs 2025) Effects of Stroke Severity on Treatment Initiated in the Emergency Department. Medical Records 7 2 354–360.
IEEE
[1]Z. Memiş vd., “Effects of Stroke Severity on Treatment Initiated in the Emergency Department”, Med Records, c. 7, sy 2, ss. 354–360, May. 2025, doi: 10.37990/medr.1620713.
ISNAD
Memiş, Zülfikar - Kuru, İrem - Gök, Sinem - İncirci, Bahar - Topcu, Adem - Ergenç, Hüseyin - Çokar, Ayşe Özlem. “Effects of Stroke Severity on Treatment Initiated in the Emergency Department”. Medical Records 7/2 (01 Mayıs 2025): 354-360. https://doi.org/10.37990/medr.1620713.
JAMA
1.Memiş Z, Kuru İ, Gök S, İncirci B, Topcu A, Ergenç H, Çokar AÖ. Effects of Stroke Severity on Treatment Initiated in the Emergency Department. Med Records. 2025;7:354–360.
MLA
Memiş, Zülfikar, vd. “Effects of Stroke Severity on Treatment Initiated in the Emergency Department”. Medical Records, c. 7, sy 2, Mayıs 2025, ss. 354-60, doi:10.37990/medr.1620713.
Vancouver
1.Zülfikar Memiş, İrem Kuru, Sinem Gök, Bahar İncirci, Adem Topcu, Hüseyin Ergenç, Ayşe Özlem Çokar. Effects of Stroke Severity on Treatment Initiated in the Emergency Department. Med Records. 01 Mayıs 2025;7(2):354-60. doi:10.37990/medr.1620713