Klinik Araştırma
BibTex RIS Kaynak Göster

Yıl 2025, Cilt: 7 Sayı: 3, 596 - 602, 09.09.2025
https://doi.org/10.37990/medr.1696466
https://izlik.org/JA79DG33MW

Öz

Kaynakça

  • Yang XJ, Sun SS. Comparison of maternal and fetal complications in elective and emergency cesarean section: a systematic review and meta-analysis. Arch Gynecol Obstet. 2017;296:503-12.
  • Gasim T, Al Jama FE, Rahman MS, Rahman J. Multiple repeat cesarean sections: operative difficulties, maternal complications and outcome. J Reprod Med. 2013;58:312-8.
  • Keag OE, Norman JE, Stock SJ. Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: systematic review and meta-analysis. PLoS Med. 2018;15:e1002494.
  • Betran AP, Torloni MR, Zhang JJ, et al. WHO working group on Caesarean section. WHO statement on caesarean section rates. BJOG. 2016;123:667-70.
  • Smith V, Hannon K, Begley C. Clinician’s attitudes towards caesarean section: a cross-sectional survey in two tertiary level maternity units in Ireland. Women and Birth. 2022;35:423-8.
  • Hacettepe University Institute of Population Studies (HUIPS). 2003 Turkey Demographic and Health Survey. https://fs.hacettepe.edu.tr/hips/dosyalar/Ara%C5%9Ft%C4%B1rmalar%20-%20raporlar/2003%20tnsa/ENG/TDHS_2003_main_report.pdf access date 13.06.2025.
  • Hacettepe University Institute of Population Studies (HUIPS). 2008 Turkey Demographic and Health Survey. https://dhsprogram.com/pubs/pdf/FR351/FR351.pdf access date 13.06.2025.
  • Hacettepe University Institute of Population Studies (HUIPS). 2018 Turkey Demographic and Health Survey. https://www.dhsprogram.com/pubs/pdf/FR372/FR372.pdf access date 13.06.2025.
  • Ye J, Betran AP, Guerrero Vela M, et al. Searching for the optimal rate of medically necessary cesarean delivery. Birth. 2014;41:237-44.
  • Reddy UM, Abuhamad AZ, Levine D, Saade GR.; Fetal Imaging Workshop Invited Participants. Fetal imaging: executive summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging Workshop. J Ultrasound Med. 2014;33:745-57.
  • Collins SL, Ashcroft A, Braun T, et al. Proposal for standardized ultrasound descriptors of abnormally invasive placenta (AIP). Ultrasound Obstet Gynecol. 2015;47:271-5.
  • Jauniaux E, Ayres-de-Campos D, Langhoff-Roos J. FIGO classification for the clinical diagnosis of placenta accreta spectrum disorders. Int J Gynaecol Obstet. 2019;146:20-4.
  • Marshall NE, Fu R, Guise JM. Impact of multiple cesarean deliveries on maternal morbidity: a systematic review. Am J Obstet Gynecol. 2011;205:262.e1-8.
  • Makoha FW, Felimban HM, Fathuddien MA, et al. Multiple caesarean section morbidity. Int J Gynaecol Obstet. 2004;87:227-32.
  • Jauniaux E, Bhide A. Prenatal ultrasound diagnosis and outcome of placenta previa accreta after cesarean delivery: a systematic review and meta-analysis. Am J Obstet Gynecol. 2017;217:27-36.
  • Silver RM. Abnormal placentation: placenta previa, vasa previa, and placenta accreta. Obstet Gynecol. 2015;126:654-68.
  • Tulandi T, Agdi M, Zarei A, et al. Adhesion development and morbidity after repeat cesarean delivery. Am J Obstet Gynecol. 2009;201:56.e1-56.e6.
  • Uygur D, Gun O, Kelekci S, et al. Multiple repeat caesarean section: is it safe?. Eur J Obstet Gynecol Reprod Biol. 2005;119:171-5.
  • Rashid M, Rashid RS. Higher order repeat caesarean sections: how safe are five or more?. BJOG. 2004;111:1090-4.
  • Kaplanoglu M. Vaginal birth after cesarean section. Arch Med Rev J. 2014;23:624-36.
  • Satitniramai S, Manonai J. Urologic injuries during gynecologic surgery, a 10‐year review. J Obstet Gynaecol Res. 2017;43:557-63.
  • Qublan HS, Tahat Y. Multiple cesarean section. The impact on maternal and fetal outcome. Saudi Med J. 2006;27:210-4.
  • Macones GA, Peipert J, Nelson DB, et al. Maternal complications with vaginal birth after cesarean delivery: a multicenter study. Am J Obstet Gynecol. 2005;193:1656-62.
  • Cahill AG, Waterman BM, Stamilio DM, et al. Higher maximum doses of oxytocin are associated with an unacceptably high risk for uterine rupture in patients attempting vaginal birth after cesarean delivery. Am J Obstet Gynecol. 2008;199:32.e1-5.
  • Oben A, Ausbeck EB, Gazi MN, et al. Association between number of prior cesareans and early preterm delivery in women with abnormal placentation. Am J Perinatol. 2012;38:326-31.

From Safety to Risk: Maternal Morbidity in Women Undergoing Multiple Repeat Cesarean Deliveries

Yıl 2025, Cilt: 7 Sayı: 3, 596 - 602, 09.09.2025
https://doi.org/10.37990/medr.1696466
https://izlik.org/JA79DG33MW

Öz

Aim: The global rise in cesarean delivery (CD) rates, especially in low- and middle-income countries, has increased the prevalence of multiple repeat cesarean deliveries (MRCDs), raising concerns about associated maternal and neonatal morbidity. The objective of this study was to assess clinical outcomes related to MRCDs by comparing women with four or more prior CDs to those with fewer.
Material and Method: This study was retrospectively conducted involving 15,811 women with singleton pregnancies who underwent CD and had a history of at least one prior CD between January 2018 and December 2022. Participants were categorized into two groups: Group 1 (≤3 prior CDs) and Group 2 (≥4 prior CDs). Maternal demographics, intraoperative and postoperative outcomes, as well as neonatal outcomes, were analyzed and evaluated across the groups.
Results: Women in Group 2 had significantly higher rates of placenta previa (7.4% vs. 0.23%), placenta accreta (1.9% vs. 0.04%), cesarean hysterectomy (1.5% vs. 0.007%), intra-abdominal adhesion (7.3% vs. 1.21%), bladder injury (1.06% vs. 0.095%), and blood transfusion (8.7% vs. 2.6%) than those in Group 1 (all p<0.001). Neonatal outcomes were also adversely affected in Group 2, with lower gestational age at delivery (37.6 vs. 38.4 weeks) and increased NICU admission rate (10.2% vs. 7.6%; p<0.001).
Conclusion: MRCDs are significantly associated with increased maternal and neonatal morbidity, particularly in women with four or more previous CDs. These findings emphasize the need for comprehensive prenatal counseling, surgical preparedness, and efforts to reduce primary CD rates, while promoting trial of labor after CD when clinically appropriate.

Etik Beyan

Approved by University of Health Sciences Etlik Zübeyde Hanım Health Care Training and Research Hospital (Date, 20.05.2021, Reference Number: 07/10).

Teşekkür

The author would like to thank all the staff in our surgical and laboratory departments for their expert assistance in collecting the data.

Kaynakça

  • Yang XJ, Sun SS. Comparison of maternal and fetal complications in elective and emergency cesarean section: a systematic review and meta-analysis. Arch Gynecol Obstet. 2017;296:503-12.
  • Gasim T, Al Jama FE, Rahman MS, Rahman J. Multiple repeat cesarean sections: operative difficulties, maternal complications and outcome. J Reprod Med. 2013;58:312-8.
  • Keag OE, Norman JE, Stock SJ. Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: systematic review and meta-analysis. PLoS Med. 2018;15:e1002494.
  • Betran AP, Torloni MR, Zhang JJ, et al. WHO working group on Caesarean section. WHO statement on caesarean section rates. BJOG. 2016;123:667-70.
  • Smith V, Hannon K, Begley C. Clinician’s attitudes towards caesarean section: a cross-sectional survey in two tertiary level maternity units in Ireland. Women and Birth. 2022;35:423-8.
  • Hacettepe University Institute of Population Studies (HUIPS). 2003 Turkey Demographic and Health Survey. https://fs.hacettepe.edu.tr/hips/dosyalar/Ara%C5%9Ft%C4%B1rmalar%20-%20raporlar/2003%20tnsa/ENG/TDHS_2003_main_report.pdf access date 13.06.2025.
  • Hacettepe University Institute of Population Studies (HUIPS). 2008 Turkey Demographic and Health Survey. https://dhsprogram.com/pubs/pdf/FR351/FR351.pdf access date 13.06.2025.
  • Hacettepe University Institute of Population Studies (HUIPS). 2018 Turkey Demographic and Health Survey. https://www.dhsprogram.com/pubs/pdf/FR372/FR372.pdf access date 13.06.2025.
  • Ye J, Betran AP, Guerrero Vela M, et al. Searching for the optimal rate of medically necessary cesarean delivery. Birth. 2014;41:237-44.
  • Reddy UM, Abuhamad AZ, Levine D, Saade GR.; Fetal Imaging Workshop Invited Participants. Fetal imaging: executive summary of a joint Eunice Kennedy Shriver National Institute of Child Health and Human Development, Society for Maternal-Fetal Medicine, American Institute of Ultrasound in Medicine, American College of Obstetricians and Gynecologists, American College of Radiology, Society for Pediatric Radiology, and Society of Radiologists in Ultrasound Fetal Imaging Workshop. J Ultrasound Med. 2014;33:745-57.
  • Collins SL, Ashcroft A, Braun T, et al. Proposal for standardized ultrasound descriptors of abnormally invasive placenta (AIP). Ultrasound Obstet Gynecol. 2015;47:271-5.
  • Jauniaux E, Ayres-de-Campos D, Langhoff-Roos J. FIGO classification for the clinical diagnosis of placenta accreta spectrum disorders. Int J Gynaecol Obstet. 2019;146:20-4.
  • Marshall NE, Fu R, Guise JM. Impact of multiple cesarean deliveries on maternal morbidity: a systematic review. Am J Obstet Gynecol. 2011;205:262.e1-8.
  • Makoha FW, Felimban HM, Fathuddien MA, et al. Multiple caesarean section morbidity. Int J Gynaecol Obstet. 2004;87:227-32.
  • Jauniaux E, Bhide A. Prenatal ultrasound diagnosis and outcome of placenta previa accreta after cesarean delivery: a systematic review and meta-analysis. Am J Obstet Gynecol. 2017;217:27-36.
  • Silver RM. Abnormal placentation: placenta previa, vasa previa, and placenta accreta. Obstet Gynecol. 2015;126:654-68.
  • Tulandi T, Agdi M, Zarei A, et al. Adhesion development and morbidity after repeat cesarean delivery. Am J Obstet Gynecol. 2009;201:56.e1-56.e6.
  • Uygur D, Gun O, Kelekci S, et al. Multiple repeat caesarean section: is it safe?. Eur J Obstet Gynecol Reprod Biol. 2005;119:171-5.
  • Rashid M, Rashid RS. Higher order repeat caesarean sections: how safe are five or more?. BJOG. 2004;111:1090-4.
  • Kaplanoglu M. Vaginal birth after cesarean section. Arch Med Rev J. 2014;23:624-36.
  • Satitniramai S, Manonai J. Urologic injuries during gynecologic surgery, a 10‐year review. J Obstet Gynaecol Res. 2017;43:557-63.
  • Qublan HS, Tahat Y. Multiple cesarean section. The impact on maternal and fetal outcome. Saudi Med J. 2006;27:210-4.
  • Macones GA, Peipert J, Nelson DB, et al. Maternal complications with vaginal birth after cesarean delivery: a multicenter study. Am J Obstet Gynecol. 2005;193:1656-62.
  • Cahill AG, Waterman BM, Stamilio DM, et al. Higher maximum doses of oxytocin are associated with an unacceptably high risk for uterine rupture in patients attempting vaginal birth after cesarean delivery. Am J Obstet Gynecol. 2008;199:32.e1-5.
  • Oben A, Ausbeck EB, Gazi MN, et al. Association between number of prior cesareans and early preterm delivery in women with abnormal placentation. Am J Perinatol. 2012;38:326-31.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kadın Hastalıkları ve Doğum
Bölüm Klinik Araştırma
Yazarlar

Gülay Balkaş 0000-0001-5211-9263

Gönderilme Tarihi 12 Mayıs 2025
Kabul Tarihi 3 Haziran 2025
Yayımlanma Tarihi 9 Eylül 2025
DOI https://doi.org/10.37990/medr.1696466
IZ https://izlik.org/JA79DG33MW
Yayımlandığı Sayı Yıl 2025 Cilt: 7 Sayı: 3

Kaynak Göster

AMA 1.Balkaş G. From Safety to Risk: Maternal Morbidity in Women Undergoing Multiple Repeat Cesarean Deliveries. Med Records. 2025;7(3):596-602. doi:10.37990/medr.1696466

Chief Editors
Prof. Dr. Berkant Özpolat, MD
Department of Thoracic Surgery, Ufuk University, Dr. Rıdvan Ege Hospital, Ankara, Türkiye

Editors
Prof. Dr. Sercan Okutucu, MD
Department of Cardiology, Ankara Lokman Hekim University, Ankara, Türkiye

Assoc. Prof. Dr. Süleyman Cebeci, MD
Department of Ear, Nose and Throat Diseases, Gazi University Faculty of Medicine, Ankara, Türkiye

Field Editors
Assoc. Prof. Dr. Doğan Öztürk, MD
Department of General Surgery, Manisa Özel Sarıkız Hospital, Manisa, Türkiye

Assoc. Prof. Dr. Birsen Doğanay, MD
Department of Cardiology, Ankara Bilkent City Hospital, Ankara, Türkiye

Assoc. Prof. Dr. Sonay Aydın, MD
Department of Radiology, Erzincan Binali Yıldırım University Faculty of Medicine, Erzincan, Türkiye

Language Editors
PhD, Dr. Evin Mise
Department of Work Psychology, Ankara University, Ayaş Vocational School, Ankara, Türkiye

Dt. Çise Nazım
Department of Periodontology, Dr. Burhan Nalbantoğlu State Hospital, Lefkoşa, North Cyprus

Statistics Editor
Dr. Nurbanu Bursa, PhD
Department of Statistics, Hacettepe University, Faculty of Science, Ankara, Türkiye

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