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Subcutaneous Reccurent Myxoid Liposarcoma

Yıl 2019, Cilt: 1 Sayı: 2, 50 - 52, 01.12.2019

Öz

Kaynakça

  • 1. Antonescu C., Ladanyi M. Myxoid liposarcoma. In: Fletcher C. D. M., Unni K. K., Mertens F., editors. World Health Organization Classification of Tumors, Pathology and Genetics of Tumors of Soft Tissue and Bone. Lyon, France: IARC Press; 2002. pp. 40–43.2. de Vreeze R. S. A., de Jong D., Haas R. L., Stewart F., van Coevorden F. Effectiveness of radiotherapy in myxoid sarcomas is associated with a dense vascular pattern. International Journal of Radiation Oncology, Biology, Physics. 2008;72(5):1480–1487. doi: 10.1016/j.ijrobp.2008.03.008. 3. Jones R. L., Fisher C., Al-Muderis O., Judson I. R. Differential sensitivity of liposarcoma subtypes to chemotherapy. European Journal of Cancer. 2005;41(18):2853–2860. doi: 10.1016/j.ejca.2005.07.023. 4. Crago AM, Dickson MA. Liposarcoma: multimodality management and future targeted therapies. Surg Oncol Clin N Am. 2016;25(4):761–73. https://doi.org/10. 1016/j.soc.2016.05.007.5. Rosenberg SA, Tepper J, Glatstein E, Costa J, Baker A, Brennan M, et al. The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy. Ann Surg. 1982;196(3):305–15.6. Trovik CS, Bauer HC, Alvegard TA, Anderson H, Blomqvist C, Berlin O, et al. Surgical margins, local recurrence and metastasis in soft tissue sarcomas: 559 surgically-treated patients from the Scandinavian Sarcoma Group Register. Eur J Cancer. 2000;36(6):710–6.7. Gronchi A, Casali PG, Mariani L, Miceli R, Fiore M, Lo Vullo S, et al. Status of surgical margins and prognosis in adult soft tissue sarcomas of the extremities: a series of patients treated at a single institution. J Clin Oncol. 2005;23(1):96–104. https://doi.org/10.1200/JCO. 2005.04.160.8. Chung PW, Deheshi BM, Ferguson PC, Wunder JS, Griffin AM, Catton CN, et al. Radiosensitivity translates into excellent local control in extremity myxoid liposarcoma: a comparison with other soft tissue sarcomas. Cancer. 2009;115(14):3254–61. https://doi. org/10.1002/cncr.24375.9. Cheng EY, Dusenbery KE, Winters MR, Thompson RC. Soft tissue sarcomas: preoperative versus postoperative radiotherapy. J Surg Oncol. 1996;61(2):90–9. https:// doi.org/10.1002/(SICI)1096-9098(199602) 61:2G90::AID-JSO293.0.CO;2-M.10. Frustaci S, Gherlinzoni F, De Paoli A, Bonetti M, Azzarelli A, Comandone A, et al. Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized Curr. Treat. Options in Oncol. (2018) 19:64 Page 11 of 13 64 cooperative trial. J Clin Oncol. 2001;19(5):1238–47. https://doi.org/10.1200/JCO.2001.19.5.1238.11. Gronchi A, Ferrari S, Quagliuolo V, Broto JM, Pousa AL, Grignani G, et al. Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial. Lancet Oncol. 2017;18(6):812–22. https://doi.org/10.1016/S1470- 2045(17)30334-0.

Subkutan Nükseden Miksoid Liposarkom

Yıl 2019, Cilt: 1 Sayı: 2, 50 - 52, 01.12.2019

Öz

Liposarcoma,
one of the most common soft-tissue sarcomas, originates from primitive
mesenchymal cells, and its diagnostic have been well established.  Myxoid liposarcoma is the second most common
histological subtype, occurring more frequently during the fourth and fifth
decades of life.

We describe a
case of recurrent myxoid liposarcoma of the right flank in 50 years old man.
Treatment of the recurrence  involved chemotherapy
neo-adjuvant (3 courses), wide surgical resection (resection R1) followed by
locoregional radiation therapy. Patient’s evolution was marked by complete remission
maintained after 12 months follow-up.





The myxoid
liposarcoma has a low rate of local failure with trimodality therapy combined
chemotherapy, radiotherapy and surgery.

Kaynakça

  • 1. Antonescu C., Ladanyi M. Myxoid liposarcoma. In: Fletcher C. D. M., Unni K. K., Mertens F., editors. World Health Organization Classification of Tumors, Pathology and Genetics of Tumors of Soft Tissue and Bone. Lyon, France: IARC Press; 2002. pp. 40–43.2. de Vreeze R. S. A., de Jong D., Haas R. L., Stewart F., van Coevorden F. Effectiveness of radiotherapy in myxoid sarcomas is associated with a dense vascular pattern. International Journal of Radiation Oncology, Biology, Physics. 2008;72(5):1480–1487. doi: 10.1016/j.ijrobp.2008.03.008. 3. Jones R. L., Fisher C., Al-Muderis O., Judson I. R. Differential sensitivity of liposarcoma subtypes to chemotherapy. European Journal of Cancer. 2005;41(18):2853–2860. doi: 10.1016/j.ejca.2005.07.023. 4. Crago AM, Dickson MA. Liposarcoma: multimodality management and future targeted therapies. Surg Oncol Clin N Am. 2016;25(4):761–73. https://doi.org/10. 1016/j.soc.2016.05.007.5. Rosenberg SA, Tepper J, Glatstein E, Costa J, Baker A, Brennan M, et al. The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy. Ann Surg. 1982;196(3):305–15.6. Trovik CS, Bauer HC, Alvegard TA, Anderson H, Blomqvist C, Berlin O, et al. Surgical margins, local recurrence and metastasis in soft tissue sarcomas: 559 surgically-treated patients from the Scandinavian Sarcoma Group Register. Eur J Cancer. 2000;36(6):710–6.7. Gronchi A, Casali PG, Mariani L, Miceli R, Fiore M, Lo Vullo S, et al. Status of surgical margins and prognosis in adult soft tissue sarcomas of the extremities: a series of patients treated at a single institution. J Clin Oncol. 2005;23(1):96–104. https://doi.org/10.1200/JCO. 2005.04.160.8. Chung PW, Deheshi BM, Ferguson PC, Wunder JS, Griffin AM, Catton CN, et al. Radiosensitivity translates into excellent local control in extremity myxoid liposarcoma: a comparison with other soft tissue sarcomas. Cancer. 2009;115(14):3254–61. https://doi. org/10.1002/cncr.24375.9. Cheng EY, Dusenbery KE, Winters MR, Thompson RC. Soft tissue sarcomas: preoperative versus postoperative radiotherapy. J Surg Oncol. 1996;61(2):90–9. https:// doi.org/10.1002/(SICI)1096-9098(199602) 61:2G90::AID-JSO293.0.CO;2-M.10. Frustaci S, Gherlinzoni F, De Paoli A, Bonetti M, Azzarelli A, Comandone A, et al. Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized Curr. Treat. Options in Oncol. (2018) 19:64 Page 11 of 13 64 cooperative trial. J Clin Oncol. 2001;19(5):1238–47. https://doi.org/10.1200/JCO.2001.19.5.1238.11. Gronchi A, Ferrari S, Quagliuolo V, Broto JM, Pousa AL, Grignani G, et al. Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial. Lancet Oncol. 2017;18(6):812–22. https://doi.org/10.1016/S1470- 2045(17)30334-0.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular İç Hastalıkları
Bölüm Olgu Sunumu
Yazarlar

Terrab Fatima Zahrae 0000-0001-6508-5066

Rajae Ennouichi Bu kişi benim 0000-0002-1518-1989

Fadoua Allouche 0000-0002-6793-4911

Zenab Alami Bu kişi benim 0000-0002-7071-2359

Touria Bouhafa Bu kişi benim 0000-0002-9857-1594

Khalid Hassouni Bu kişi benim 0000-0002-8258-2360

Kabul Tarihi 11 Kasım 2019
Yayımlanma Tarihi 1 Aralık 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 1 Sayı: 2

Kaynak Göster

AMA Fatima Zahrae T, Ennouichi R, Allouche F, Alami Z, Bouhafa T, Hassouni K. Subcutaneous Reccurent Myxoid Liposarcoma. Med Records. Aralık 2019;1(2):50-52.

Chief Editors
Prof. Dr. Berkant Özpolat, MD
Department of Thoracic Surgery, Ufuk University, Dr. Rıdvan Ege Hospital, Ankara, Türkiye

Editors
Prof. Dr. Sercan Okutucu, MD
Department of Cardiology, Ankara Lokman Hekim University, Ankara, Türkiye

Assoc. Prof. Dr. Süleyman Cebeci, MD
Department of Ear, Nose and Throat Diseases, Gazi University Faculty of Medicine, Ankara, Türkiye

Field Editors
Assoc. Prof. Dr. Doğan Öztürk, MD
Department of General Surgery, Manisa Özel Sarıkız Hospital, Manisa, Türkiye

Assoc. Prof. Dr. Birsen Doğanay, MD
Department of Cardiology, Ankara Bilkent City Hospital, Ankara, Türkiye

Assoc. Prof. Dr. Sonay Aydın, MD
Department of Radiology, Erzincan Binali Yıldırım University Faculty of Medicine, Erzincan, Türkiye

Language Editors
PhD, Dr. Evin Mise
Department of Work Psychology, Ankara University, Ayaş Vocational School, Ankara, Türkiye

Dt. Çise Nazım
Department of Periodontology, Dr. Burhan Nalbantoğlu State Hospital, Lefkoşa, North Cyprus

Statistics Editor
Dr. Nurbanu Bursa, PhD
Department of Statistics, Hacettepe University, Faculty of Science, Ankara, Türkiye

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