Peripheral Giant Cell Granuloma in Maxilla: Case Report

Abstract

Peripheral giant cell granuloma (PGCG) is a reactive exophytic lesion that occurs on the gingiva and alveolar crest due to local irritation and trauma. It is usually localized in the mandible and it is frequently seen in 4-6 decades. The clinical appearance is bluish red, lesion similar to liver tissue, usually smaller than 2 cm. Its treatment is surgical excision. Very rarely, recurrence is observed. In this case report, the treatment and follow-up of the lesion located in the maxillary premolar region and diagnosed as PDHG histopathologically in a 51-year-old female patient were presented.

Keywords

• Peripheral giant cell granuloma
• granuloma
• maxilla

Maksillada Periferal Dev Hücreli Granüloma: Olgu Sunumu

Öz

Periferal dev hücreli granüloma (PDHG) lokal irritasyon ve travma sebebiyle gingiva ve alveoler kret üzerinde ortaya çıkan reaktif
ekzofitik bir lezyondur. Genellikle mandibulada lokalizedir ve sıklıkla 4.-6. dekatlarda görülür. Klinik görünümü mavimsi kırmızı renkte,
karaciğer dokusuna benzeyen genellikle 2 cm’den küçük lezyondur. Tedavisi cerrahi eksizyondur. Çok nadir olarak nüks görülmektedir.
Bu olgu raporunda 51 yaşında kadın hastada maksiller premolar bölgede bulunan ve histopatolojik olarak PDHG tanısı konulmuş
lezyonun tedavisi ve takibi sunulmuştur.

Anahtar Kelimeler

• Periferal dev hücreli granülom, granüloma, maksilla, oral kavite

Kaynakça

1. 1. Verma PK, Srivastava R, Baranwal HC, Chaturvedi TP, Gautam A, Singh A. Pyogenicgranuloma—hyperplastic lesion of the gingiva: case reports. Open Dent J 2012;6(1):153-6.
2. 2. Vaishali K, Raghavendra B, Nishit S. Peripheral ossifying fibroma. J Indian Acad Oral Med Pathol 2008;20(2):54-6.
3. 3. Regezi JA, Sciubba JJ: Oral Pathology Clinical Pathologic Correlations, John Dolan (ed) Reactive lesions. 5th edition. W.B. Saunders Company, Philadelphia, 2008; 112-113.
4. 4. Dojcinovic I, Richter M, Lombardi T. Occurrence of a pyogenic granuloma in relation to a dental implant. J Oral Maxillofac Surg 2010;68(8):1874-6.
5. 5. Cloutier M, Charles M, Carmichael RP, S´andor GKB. Ananalysis of peripheral giant cell granuloma associated with dental implant treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103(5):618-22.
6. 6. Katsikeris N, Kakarantza –Angelopoulou E, Angelopoulos AP. Peripheral giant cell granuloma: clinico- pathologic study 224 new cases and 956 reported cases. Int J Oral Maxillofac Surg 1988;17(2):94-9.
7. 7. Bodner L, Peist M, Gatot A, Fliss DM. Growth potential of peripheral giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;83(5):548-51.
8. 8. Günhan Ö: Oral ve Maksillofasiyal Patoloji. 1. Baskı. İstanbul: Quintessence Yayıncılık; 2015. P. 120-1.

9. 9. Mannem S, Chava VK. Managament of an unusual peripheral giant cell granuloma: A diagnostic dilemma. Contemp Clin Dent 2012;3(1):93-6.
10. 10. Gümüşok M, Özle M, Okur B, et al. Multiple Large Peripheral Giant Cell Granüloma: A case report. Balıkesir Health Sciences Journal 2015;4(2):103-6.
11. 11. Yalçın E, Ertaş Ü, Altaş S. Periferal Dev Hücreli Granuloma: Retrospektif çalışma. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2010;20(1):34-37.
12. 12. Motamedi MH, Eshghyar N, Jafari SM, Lassemi E, Navi F, Abbas FM,et al. Peripheral and central giant cell granulomas of the jaws: a demographic study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103(6):e39-43.
13. 13. Demirkol M, Aras MH, Kara Mİ, Yanık S, Ay S. Çenelerde Görülen Periferal Dev Hücreli Granülomalar: 16 Olgu Serisi. Turkiye Klinikleri J Dental Sci 2012;18(3):237-241.
14. 14. Flaitz CM. Peripheral giant cell granuloma: a potentially agressive lesion in children. Pediatr Dent 2000;22:232-3.
15. 15. Mighell AJ, Robinson PA, Hume WJ. Peripheral giant cell granuloma: a clinical study of 77 cases from 62 patients and literature review. Oral Dis 1995;1:12-19.