Araştırma Makalesi

Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident

Cilt: 3 Sayı: 3 1 Eylül 2021
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Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident

Öz

Aim: The study aimed at assessing effects of long-term 32-hours continuous shifts on leptin, melatonin, sex hormones, IL-1β, TNF-α, IL-6, hematological parameters, sleep quality and attention performance in female pediatric residents (FPR).
Materials and Methods: FPR working under 32 hours continuous shifts (08:00-08:00h after 08:00-17:00h, n=10) were compared to female health professionals working in day-time hours (08:00-16:00h, n=10). Vital parameters, glucose, leptin, melatonin, estrogen, progesterone, IL-1β, TNF-α, and IL-6 concentrations, complete blood count (CBC) and erythrocyte sedimentation rate (ESR) were measured. The participants were also requested to fill in sleep quality questionnaires and visual attention test.
Results: In the study; eosinophil ratio (p=0.015), hemoglobin (p=0.010), hematocrit (p=0.012), progesterone (p=0.008), TNF-α, (p=0.000), IL-1beta and (p= 0.003) IL-6 levels (p= 0.000) were found significantly higher in FPR. In addition, it was found that FPR had difficulty in waking up in the mornings (p = 0.000), had bad dreams (p = 0.040), and had poor sleep quality (p = 0.010). FPR had better attention performance (p=0.000).
Conclusion: Although attention performance was higher in FPR, data suggest that long-term continuous 32-hour shift system activates inflammatory response, disturbs ovarian steroid production and reduces sleep quality. Alltogether, these may culminate in inflammatory diseases or reproductive problems.  

Anahtar Kelimeler

Destekleyen Kurum

Inonu University, Scientific Research Projects Unit

Proje Numarası

Project No. 2017/649

Teşekkür

I wold like to thank everyone contributed to this study.

Kaynakça

  1. 1. Brum MCB, Filho FFD, Schnorr CC, et al. Shift work and its association with metabolic disorders. Diabetol Metab Syndr. 2015;7:45. https://doi.org/10.1186/s13098-015-0041-4.
  2. 2. Wilson JL. The impact of shift patterns on healthcare professionals. J Nurs Manag. 2002;10:211–9. https://doi.org/10.1046/j.1365-2834.2002.00308.x.
  3. 3. Harrington JM. Health effects of shift work and extended hours of work. Occup Environ Med. 2001;58:68–72. https://doi.org/10.1136/oem.58.1.68.
  4. 4. Reinhardt ÉL, Fernandes PACM, Markus RP, et al. Night work effects on salivary cytokines TNF, IL-1β and IL-6. Chronobiol Int. 2019;36:11–26. https://doi.org/10.1080/07420528.2018.1515771.
  5. 5. Harrington JM. Shift work and health--a critical review of the literature on working hours. Ann Acad Med Singapore. 1994;23:699–705.
  6. 6. Sallinen M, Kecklund G. Shift work, sleep, and sleepiness - differences between shift schedules and systems. Scand J Work Environ Health. 2010;36:121–33. https://doi.org/10.5271/sjweh.2900.
  7. 7. Åkerstedt T, Garefelt J, Richter A, et al. Work and Sleep—A Prospective Study of Psychosocial Work Factors, Physical Work Factors, and Work Scheduling. Sleep 2015;38:1129–36. https://doi.org/10.5665/sleep.4828.
  8. 8. Van Someren EJW, Riemersma-Van Der Lek RF. Live to the rhythm, slave to the rhythm. Sleep Med Rev. 2007;11:465–84. https://doi.org/10.1016/j.smrv.2007.07.003.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri

Bölüm

Araştırma Makalesi

Yazarlar

Yayımlanma Tarihi

1 Eylül 2021

Gönderilme Tarihi

28 Temmuz 2021

Kabul Tarihi

20 Ağustos 2021

Yayımlandığı Sayı

Yıl 2021 Cilt: 3 Sayı: 3

DOI

https://doi.org/10.37990/medr.975759

IZ

https://izlik.org/JA98YH28CN

Kaynak Göster

RIS / Bibtex
APA
Çakan, P., & Yıldız, S. (2021). Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident. Medical Records, 3(3), 245-253. https://doi.org/10.37990/medr.975759
AMA
1.Çakan P, Yıldız S. Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident. Med Records. 2021;3(3):245-253. doi:10.37990/medr.975759
Chicago
Çakan, Pınar, ve Sedat Yıldız. 2021. “Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident”. Medical Records 3 (3): 245-53. https://doi.org/10.37990/medr.975759.
EndNote
Çakan P, Yıldız S (01 Eylül 2021) Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident. Medical Records 3 3 245–253.
IEEE
[1]P. Çakan ve S. Yıldız, “Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident”, Med Records, c. 3, sy 3, ss. 245–253, Eyl. 2021, doi: 10.37990/medr.975759.
ISNAD
Çakan, Pınar - Yıldız, Sedat. “Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident”. Medical Records 3/3 (01 Eylül 2021): 245-253. https://doi.org/10.37990/medr.975759.
JAMA
1.Çakan P, Yıldız S. Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident. Med Records. 2021;3:245–253.
MLA
Çakan, Pınar, ve Sedat Yıldız. “Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident”. Medical Records, c. 3, sy 3, Eylül 2021, ss. 245-53, doi:10.37990/medr.975759.
Vancouver
1.Pınar Çakan, Sedat Yıldız. Long-Term 32-Hours Continuous Shifts Increases Progesterone, IL-1β, TNF-α, IL-6, Eosinophil Count and Attention Performance in Female Pediatric Resident. Med Records. 01 Eylül 2021;3(3):245-53. doi:10.37990/medr.975759