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Ciddi Epistaksis olan Hastalarda Rutin Koagülasyon Teslerinin Değerlendirmesi

Yıl 2021, Cilt: 3 Sayı: 3, 210 - 213, 01.09.2021
https://doi.org/10.37990/medr.904878

Öz

Amaç: Epistaksis yönetiminde koagülasyon testlerinin gerekli olmadığını gösteren çalışmalar mevcuttur. Bu çalışmanın amacı, müdahale gerektiren ciddi burun kanamalarında pıhtılaşma testlerinin gerekli olup olmadığını ve ilaçlarla ilişkisini araştırmaktır..
Materyal ve Metot: Çalışmaya Acil Servis’e burun kanaması ile başvurmuş 16 yaş üstü, anterior veya posterior burun tamponu konulan veya nazal mukozaya koterizasyon uygulnan hastalar dahil edildi. Hastalara ait demografik veriler, tam kan sayımı, koagülasyon testleri, kullandığı antikoagülan ve anti-trombosit ilaçlar, kanamayı durdurmak için kullanılan yöntem ve kan transfüzyonu veya koagülasyon bozukluğu için kan ürünü alıp almadığı kaydedildi.
Bulgular: Toplam 469 hastadan 141 (%30,2)’inin koagülasyon testlerinin çalışıldığı bulundu. Antikoagülan kullanan hastaların PT, aPTT ve INR değerleri anlamlı olarak yüksek bulunurken (sırasıyla p<0,001, p=0,003, p<0,001) trombosit ve hemoglobin değerlerinin anti-trombosit ve antikoagülan kullanımı ile ilişkili olmadığı bulundu (sırasıyla p=0.304, p=0.098). Hastalar herhangi bir koagülasyon veya kanama parametresinde bozulma olan ve olmayan olarak iki gruba ayrıldı. Hemoglobin değerleri açısından gruplar arasında anlamlı fark bulunurken (p=0,006), kan transfüzyonu veya koagülasyon bozukluğu için kan ürünü replasmanına ihtiyaç duyan hasta saptanmadı.
Sonuç: Konservatif yöntemlerle durdurulamayan epistaksisi olan ve antitrombosit ilaç kullanan hastalarda tedavide fark yaratmadığı için rutin pıhtılaşma testi yapılmasına gerek yoktur. Antikoagülan kullanan hastalarda sonuçlara göre pıhtılaşma testleri yapılmayabilir.

Kaynakça

  • 1. Purkey MR, Seeskin Z, Chandra R. Seasonal variation and predictors of epistaxis. Laryngoscope 2014; 124(9):2028–33.
  • 2. Riviello RJ. Otolaryngologic procedures. In: Clinical Procedures in Emergency Medicine, 4th, Roberts JR, Hedges JR (Eds), WB Saunders, Philadelphia 2004; p.1300.
  • 3. Awan MS, Iqbal M, Imam SZ. Epistaxis: when are coagulation studies justified? Emerg Med J 2008; 25(3):156–157.
  • 4. Horton JD, Bushwick B Warfarin therapy: evolving strategies in anticoagulation. Am Fam Physician 1999; 59:635–646.
  • 5. Béquignon E, Teissier N, Gauthier A, et al. Emergency department care of childhood epistaxis. Emerg Med J. 2017; 34:543–548.
  • 6. Beck R, Sorge M, Schneider A, Dietz A: Current approaches to epistaxis treatment in primary and secondary care. Dtsch Arztebl Int 2018; 115: 12–22.
  • 7. Nitu IC, Perry DJ, Lee CA. Clinical experience with the use of clotting factor concentrates in oral anticoagulation reversal. Clin Lab Haematol. 1998; 20(6):363.
  • 8. Murer K, Ahmad N, Roth BA, Holzmann D, Soyka MB. THREAT helps to identify epistaxis patients requiring blood transfusions. Journal of Otolaryngology. Head and Neck Surgery 2013; 42:4.
  • 9. Barlow DW, Deleyiannis WB, Pinczower EF. Effectiveness of surgical management of epistaxis at a tertiary care center. Laryngoscope 1997; 107(1):21–24.

Evaluation of Routine Coagulation Testing Requirements in Patients with Severe Epistaxis

Yıl 2021, Cilt: 3 Sayı: 3, 210 - 213, 01.09.2021
https://doi.org/10.37990/medr.904878

Öz

Aim: There are studies about coagulation parameters are not required in the management of epistaxis. The aim of the present study was to investigate whether or not coagulation tests are required and its relationship with medications in severe epistaxis cases that require intervention.
Material and Method: The patients above 16 years who had presented to emergency department due to epistaxis, who had undergone anterior/posterior nasal packing or electro-cautery to the nasal mucosa were included the study. The demographic characteristics, blood count, coagulation test, anti-platelet and anti-coagulant medications, the procedures carried out for stopping bleeding, whether reversal treatment or blood transfusion was needed were recorded.
Results: A total of 469 patients, it was found that coagulation parameters had been tested in 141(30.2%). While PT, aPTT and INR values of the anti-coagulant using patients were significantly higher(p<0.001, p=0.003, p<0.001, respectively), the platelet and hemoglobin values were not found to be associated with anti-platelet drug and anti-coagulant use(p=0.304, p=0.098, respectively). The patients were allocated to two groups as those any parameter of whom was impaired or not. While a significant difference was found between the groups with regard to hemoglobin values(p=0.006), no patients were determined to need reversal treatment or hemoglobin replacement.
Conclusion: Routine coagulation testing is not required for patients who have epistaxis that cannot be stopped with conservative methods and who are using anti-platelet drugs as it does not lead to a difference in treatment. Coagulation tests may not be performed in patients who use anti-coagulants based on the results.

Kaynakça

  • 1. Purkey MR, Seeskin Z, Chandra R. Seasonal variation and predictors of epistaxis. Laryngoscope 2014; 124(9):2028–33.
  • 2. Riviello RJ. Otolaryngologic procedures. In: Clinical Procedures in Emergency Medicine, 4th, Roberts JR, Hedges JR (Eds), WB Saunders, Philadelphia 2004; p.1300.
  • 3. Awan MS, Iqbal M, Imam SZ. Epistaxis: when are coagulation studies justified? Emerg Med J 2008; 25(3):156–157.
  • 4. Horton JD, Bushwick B Warfarin therapy: evolving strategies in anticoagulation. Am Fam Physician 1999; 59:635–646.
  • 5. Béquignon E, Teissier N, Gauthier A, et al. Emergency department care of childhood epistaxis. Emerg Med J. 2017; 34:543–548.
  • 6. Beck R, Sorge M, Schneider A, Dietz A: Current approaches to epistaxis treatment in primary and secondary care. Dtsch Arztebl Int 2018; 115: 12–22.
  • 7. Nitu IC, Perry DJ, Lee CA. Clinical experience with the use of clotting factor concentrates in oral anticoagulation reversal. Clin Lab Haematol. 1998; 20(6):363.
  • 8. Murer K, Ahmad N, Roth BA, Holzmann D, Soyka MB. THREAT helps to identify epistaxis patients requiring blood transfusions. Journal of Otolaryngology. Head and Neck Surgery 2013; 42:4.
  • 9. Barlow DW, Deleyiannis WB, Pinczower EF. Effectiveness of surgical management of epistaxis at a tertiary care center. Laryngoscope 1997; 107(1):21–24.
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Cerrahi
Bölüm Özgün Makaleler
Yazarlar

Bora Çekmen 0000-0003-3348-8375

Öner Bozan 0000-0002-4195-2601

Şeref Emre Atiş 0000-0002-5094-6000

Sevilay Sema Ünver 0000-0002-5074-3545

Kamil Kokulu 0000-0002-6132-0898

Asım Kalkan 0000-0002-5800-0201

Yayımlanma Tarihi 1 Eylül 2021
Kabul Tarihi 13 Temmuz 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 3 Sayı: 3

Kaynak Göster

AMA Çekmen B, Bozan Ö, Atiş ŞE, Ünver SS, Kokulu K, Kalkan A. Evaluation of Routine Coagulation Testing Requirements in Patients with Severe Epistaxis. Med Records. Eylül 2021;3(3):210-213. doi:10.37990/medr.904878

         

Chief Editors
Assoc. Prof. Zülal Öner
Address: İzmir Bakırçay University, Department of Anatomy, İzmir, Turkey

Assoc. Prof. Deniz Şenol
Address: Düzce University, Department of Anatomy, Düzce, Turkey

E-mail: medrecsjournal@gmail.com

Publisher:
Medical Records Association (Tıbbi Kayıtlar Derneği)
Address: Düzce / Türkiye


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