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Development of Artificial Intelligence Based Clinical Decision Support System on Medical Images for the Classification of COVID-19

Yıl 2023, Cilt: 5 Sayı: 1, 20 - 3, 15.01.2023
https://doi.org/10.37990/medr.1130194

Öz

Aim: The first imaging method to play an vital role in the diagnosis of COVID-19 illness is the chest X-ray. Because of the abundance of large-scale annotated picture datasets, convolutional neural networks (CNNs) have shown considerable performance in image recognition/classification. The current study aims to construct a successful deep learning model that can distinguish COVID-19 from healthy controls using chest X-ray images.
Material and Methods: The dataset in the study consists of subjects with 912 negative and 912 positive PCR results. A prediction model was built using VGG-16 with transfer learning for classifying COVID-19 chest X-ray images. The data set was split at random into 80% training and 20% testing groups.
Results: The accuracy, F1 score, sensitivity, specificity, positive and negative values from the model that can successfully distinguish COVID-19 from healthy controls are 97.3%, 97.3%, 97.8%, 96.7%, 96.7%, and 97.8% regarding the testing dataset, respectively.
Conclusion: The suggested technique might greatly improve on current radiology-based methodologies and serve as a beneficial tool for clinicians/radiologists in diagnosing and following up on COVID-19 patients.

Destekleyen Kurum

Inonu University scientific research projects coordination unit

Proje Numarası

TOA-2020-2204

Teşekkür

We would like to acknowledge the Inonu University scientific research projects coordination unit for their support with the TOA-2020-2204 project.

Kaynakça

  • 1. Guo H, Zhou Y, Liu X, Tan J. The impact of the COVID-19 epidemic on the utilization of emergency dental services. J Dental Sci. 2020;15:564-7.
  • 2. Akbulut S, Yağın FH, Çolak C. Prediction of COVID-19 based on genomic biomarkers of metagenomic next-generation sequencing (mNGS) Data using artificial intelligence technology. Erciyes Med J. 2022;44:544–8.
  • 3. Cansel N, Karaca Y, Yağin FH. Evaluation of Coronavirus Phobia and Depression in Patients With Cardiovascular Disease. Kahramanmaraş KSU Medical Journal.17:163-71.
  • 4. Yaylaci S, Dheir H, Şenocak D, et al. The effects of favipiravir on hematological parameters of covıd-19 patients. Revista Associação Méd Brasileira. 2020;66:65-70.
  • 5. Kassania SH, Kassanib PH, Wesolowskic MJ, et al. Automatic detection of coronavirus disease (COVID-19) in X-ray and CT images: a machine learning based approach. Biocybern Biomed Eng. 2021;41:867-79.
  • 6. Huang P, Liu T, Huang L, et al. Use of chest CT in combination with negative RT-PCR assay for the 2019 novel coronavirus but high clinical suspicion. Radiology. 2020;295:22-3.
  • 7. Perçin İ, Yağin H, Arslan AK, Çolak C, editors. An Interactive Web Tool for Classification Problems Based on Machine Learning Algorithms Using Java Programming Language: Data Classification Software. 2019 3rd International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT); 2019: IEEE.
  • 8. Aggarwal P, Mishra NK, Fatimah B, et al. COVID-19 image classification using deep learning: Advances, challenges and opportunities. Comput Bio Med. 2022:144:105350.
  • 9. Madaan V, Roy A, Gupta C, et al. XCOV Net: chest X-ray image classification for COVID-19 early detection using convolutional neural networks. New Gener Comput. 2021;39:583-97.
  • 10. Reshi AA, Rustam F, Mehmood A, et al. An efficient CNN model for COVID-19 disease detection based on X-ray image classification. Complexity. 2021;1-12.
  • 11. Al-Zubaidi EA, Mijwil MM. Medical image classification for coronavirus disease (COVID-19) using convolutional neural Networks. Iraqi Jo Sci. 2021:2740-7.
  • 12. Perçın İ, Yağin FH, Güldoğan E, et al. ARM: an interactive web software for association rules mining and an application in medicine. 2019 International Artificial Intelligence and Data Processing Symposium (IDAP); 2019: IEEE.
  • 13. Yağin FH, Yağin B, Arslan AK, Çolak C. Comparison of performances of associative classification methods for cervical cancer prediction: observational study. Turk Clinics J Biostatistics. 2021;13.
  • 14. Yilmaz R, Yağin FH. Early Detection of Coronary Heart Disease Based on Machine Learning Methods. Medical Records. 2022;4:1-6.
  • 15. Yousri D, Abd Elaziz M, Abualigah L, et al. COVID-19 X-ray images classification based on enhanced fractional-order cuckoo search optimizer using heavy-tailed distributions. Applied Soft Computing. 2021;101:107052.
  • 16. Apostolopoulos ID, Mpesiana TA. Covid-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks. Phys Eng Sci Med. 2020;43:635-40.
  • 17. Alqudah AM. Augmented COVID-19 X-ray images dataset. Mendeley Data, v4. 2020.
  • 18. Yilmaz R, Yağin FH. A Comparative Study for the Prediction of Heart Attack Risk and Associated Factors Using MLP and RBF Neural Networks. J Cognitive Systems. 2021;6:51-4.
  • 19. Theckedath D, Sedamkar R. Detecting affect states using VGG16, ResNet50 and SE-ResNet50 networks. SN Computer Sci. 2020;1:1-7.
  • 20. Tammina S. Transfer learning using VGG-16 with deep convolutional neural network for classifying images. Int J Scientific Research Publications (IJSRP). 2019;9:143-50.
  • 21. Simonyan K, Zisserman A. Very deep convolutional networks for large-scale image recognition. arXiv preprint arXiv:14091556. 2014.
  • 22. Srivastava S, Kumar P, Chaudhry V, Singh A. Detection of ovarian cyst in ultrasound images using fine-tuned VGG-16 deep learning network. SN Computer Science. 2020;1:1-8.
  • 23. Yasar S, Yagin FH, Arslan AK, et al. Interactive web-based software for evaluating diagnostic tests and roc curve analyses in health sciences. Annals Med Research. 2021;28:2012-8.
  • 24. Paksoy N, Yağin FH. Artificial intelligence-based colon cancer prediction by identifying genomic biomarkers. Med Records. 2022;4:196-202.
  • 25. Yağin FH, Güldoğan E, Ucuzal H, Çolak C. A Computer-Assisted Diagnosis Tool for Classifying COVID-19 based on Chest X-Ray Images. Konuralp Med J. 2021;13:438-45.
  • 26. Wang D, Mo J, Zhou G,et al. An efficient mixture of deep and machine learning models for COVID-19 diagnosis in chest X-ray images. PloS One. 2020;15:e0242535.
  • 27. Rasheed J, Hameed AA, Djeddi C, et al. A machine learning-based framework for diagnosis of COVID-19 from chest X-ray images. Interdiscip Sci. 2021;13:103-17.
Yıl 2023, Cilt: 5 Sayı: 1, 20 - 3, 15.01.2023
https://doi.org/10.37990/medr.1130194

Öz

Proje Numarası

TOA-2020-2204

Kaynakça

  • 1. Guo H, Zhou Y, Liu X, Tan J. The impact of the COVID-19 epidemic on the utilization of emergency dental services. J Dental Sci. 2020;15:564-7.
  • 2. Akbulut S, Yağın FH, Çolak C. Prediction of COVID-19 based on genomic biomarkers of metagenomic next-generation sequencing (mNGS) Data using artificial intelligence technology. Erciyes Med J. 2022;44:544–8.
  • 3. Cansel N, Karaca Y, Yağin FH. Evaluation of Coronavirus Phobia and Depression in Patients With Cardiovascular Disease. Kahramanmaraş KSU Medical Journal.17:163-71.
  • 4. Yaylaci S, Dheir H, Şenocak D, et al. The effects of favipiravir on hematological parameters of covıd-19 patients. Revista Associação Méd Brasileira. 2020;66:65-70.
  • 5. Kassania SH, Kassanib PH, Wesolowskic MJ, et al. Automatic detection of coronavirus disease (COVID-19) in X-ray and CT images: a machine learning based approach. Biocybern Biomed Eng. 2021;41:867-79.
  • 6. Huang P, Liu T, Huang L, et al. Use of chest CT in combination with negative RT-PCR assay for the 2019 novel coronavirus but high clinical suspicion. Radiology. 2020;295:22-3.
  • 7. Perçin İ, Yağin H, Arslan AK, Çolak C, editors. An Interactive Web Tool for Classification Problems Based on Machine Learning Algorithms Using Java Programming Language: Data Classification Software. 2019 3rd International Symposium on Multidisciplinary Studies and Innovative Technologies (ISMSIT); 2019: IEEE.
  • 8. Aggarwal P, Mishra NK, Fatimah B, et al. COVID-19 image classification using deep learning: Advances, challenges and opportunities. Comput Bio Med. 2022:144:105350.
  • 9. Madaan V, Roy A, Gupta C, et al. XCOV Net: chest X-ray image classification for COVID-19 early detection using convolutional neural networks. New Gener Comput. 2021;39:583-97.
  • 10. Reshi AA, Rustam F, Mehmood A, et al. An efficient CNN model for COVID-19 disease detection based on X-ray image classification. Complexity. 2021;1-12.
  • 11. Al-Zubaidi EA, Mijwil MM. Medical image classification for coronavirus disease (COVID-19) using convolutional neural Networks. Iraqi Jo Sci. 2021:2740-7.
  • 12. Perçın İ, Yağin FH, Güldoğan E, et al. ARM: an interactive web software for association rules mining and an application in medicine. 2019 International Artificial Intelligence and Data Processing Symposium (IDAP); 2019: IEEE.
  • 13. Yağin FH, Yağin B, Arslan AK, Çolak C. Comparison of performances of associative classification methods for cervical cancer prediction: observational study. Turk Clinics J Biostatistics. 2021;13.
  • 14. Yilmaz R, Yağin FH. Early Detection of Coronary Heart Disease Based on Machine Learning Methods. Medical Records. 2022;4:1-6.
  • 15. Yousri D, Abd Elaziz M, Abualigah L, et al. COVID-19 X-ray images classification based on enhanced fractional-order cuckoo search optimizer using heavy-tailed distributions. Applied Soft Computing. 2021;101:107052.
  • 16. Apostolopoulos ID, Mpesiana TA. Covid-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks. Phys Eng Sci Med. 2020;43:635-40.
  • 17. Alqudah AM. Augmented COVID-19 X-ray images dataset. Mendeley Data, v4. 2020.
  • 18. Yilmaz R, Yağin FH. A Comparative Study for the Prediction of Heart Attack Risk and Associated Factors Using MLP and RBF Neural Networks. J Cognitive Systems. 2021;6:51-4.
  • 19. Theckedath D, Sedamkar R. Detecting affect states using VGG16, ResNet50 and SE-ResNet50 networks. SN Computer Sci. 2020;1:1-7.
  • 20. Tammina S. Transfer learning using VGG-16 with deep convolutional neural network for classifying images. Int J Scientific Research Publications (IJSRP). 2019;9:143-50.
  • 21. Simonyan K, Zisserman A. Very deep convolutional networks for large-scale image recognition. arXiv preprint arXiv:14091556. 2014.
  • 22. Srivastava S, Kumar P, Chaudhry V, Singh A. Detection of ovarian cyst in ultrasound images using fine-tuned VGG-16 deep learning network. SN Computer Science. 2020;1:1-8.
  • 23. Yasar S, Yagin FH, Arslan AK, et al. Interactive web-based software for evaluating diagnostic tests and roc curve analyses in health sciences. Annals Med Research. 2021;28:2012-8.
  • 24. Paksoy N, Yağin FH. Artificial intelligence-based colon cancer prediction by identifying genomic biomarkers. Med Records. 2022;4:196-202.
  • 25. Yağin FH, Güldoğan E, Ucuzal H, Çolak C. A Computer-Assisted Diagnosis Tool for Classifying COVID-19 based on Chest X-Ray Images. Konuralp Med J. 2021;13:438-45.
  • 26. Wang D, Mo J, Zhou G,et al. An efficient mixture of deep and machine learning models for COVID-19 diagnosis in chest X-ray images. PloS One. 2020;15:e0242535.
  • 27. Rasheed J, Hameed AA, Djeddi C, et al. A machine learning-based framework for diagnosis of COVID-19 from chest X-ray images. Interdiscip Sci. 2021;13:103-17.
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Özgün Makaleler
Yazarlar

Cemil Çolak 0000-0001-5406-098X

Ahmet Kadir Arslan 0000-0002-8109-0380

Hasan Ucuzal 0000-0003-0721-2631

Adem Köse 0000-0002-1853-1243

İsmail Okan Yıldırım 0000-0002-3641-0103

Emek Güldoğan 0000-0002-5436-8164

Mehmet Cengiz Çolak 0000-0003-0993-243X

Proje Numarası TOA-2020-2204
Erken Görünüm Tarihi 15 Ocak 2023
Yayımlanma Tarihi 15 Ocak 2023
Kabul Tarihi 21 Temmuz 2022
Yayımlandığı Sayı Yıl 2023 Cilt: 5 Sayı: 1

Kaynak Göster

AMA Çolak C, Arslan AK, Ucuzal H, Köse A, Yıldırım İO, Güldoğan E, Çolak MC. Development of Artificial Intelligence Based Clinical Decision Support System on Medical Images for the Classification of COVID-19. Med Records. Ocak 2023;5(1):20-3. doi:10.37990/medr.1130194

 Chief Editors

Assoc. Prof. Zülal Öner
Address: İzmir Bakırçay University, Department of Anatomy, İzmir, Turkey

Assoc. Prof. Deniz Şenol
Address: Düzce University, Department of Anatomy, Düzce, Turkey

E-mail: medrecsjournal@gmail.com

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