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The Effect of Vagus Nerve Stimulation Applications on Taste and Smell Loss in COVID-19 Syndrome: Case Report

Yıl 2023, Cilt: 5 Sayı: 3, 655 - 8, 18.09.2023
https://doi.org/10.37990/medr.1262924

Öz

Loss of the sense of taste and smell is a common side effect of Covid 19. It is thought that transcutaneous ear vagus nerve stimulation may affect taste and smell as a result of neural connections. We present a 27-year-old female participant diagnosed with loss of taste and smell for more than 1 year. The Connecticut Chemosensory Clinical Research Center (CCCRC) olfactory test was used to test the sense of smell. To test the sense of taste, 3 drops of taste test were applied. It was found that during the application period of 1 session per day for 15 days, there was a progressive improvement in the sense of taste and smell. However, it was found that the effect was not significant in restoring the sense of smell and the ability to distinguish odors.

Destekleyen Kurum

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Proje Numarası

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Teşekkür

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Kaynakça

  • 1. Umakanthan S, Sahu P, Ranade A V, et al. Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Postgrad Med JPostgrad Med J. 2020;96:753- 8.
  • 2. Najafloo R, Majidi J, Asghari A, et al. Mechanism of anosmia caused by symptoms of COVID-19 and emerging treatments. ACS Chem Neurosci. 2021;12:3795-805.
  • 3. Khani E, Khiali S, Beheshtirouy S, Entezari-Maleki T. Potential pharmacologic treatments for COVID-19 smell and taste loss: a comprehensive review. Eur J Pharmacol. 2021;912:174582.
  • 4. Cain WS, Goodspeed RB, Gent JF, et al. Evaluation of olfactory dysfunction in the Connecticut chemosensory clinical research center. The Laryngoscope. 1998;98:83-8.
  • 5. Veyseller B, Ozucer B, Karaaltin AB, et al. Connecticut (CCCRC) olfactory test: normative values in 426 healthy volunteers. Indian J Otolaryngol Head Neck Surg. 2014;66:31-4.
  • 6. Sperling W, Biermann T, Spannenberger R, et al. Changes in gustatory perceptions of patients with major depression treated with vagus nerve stimulation (VNS). Pharmacopsychiatry. 2011;44:67–71.
  • 7. Whitcroft KL, Hummel T. Olfactory Dysfunction in COVID-19: diagnosis and management. JAMA. 2020;323:2512-4.
  • 8. Haehner A, Draf J, Dräger S, De With K, Hummel T. Predictive value of sudden olfactory loss in the diagnosis of COVID-19. ORL. 2020;82:175–80.
  • 9. Moein ST, Hashemian SMR, Mansourafshar B, et al. Smell dysfunction: a biomarker for COVID-19. Int Forum Allergy Rhinol. 2020;10:944-50.
  • 10. Mueller C, Temmel AFP, Quint C, Rieger A, Hummel T. Olfactory function in HIV-positive subjects. Acta Otolaryngol. 2002;122:67-71.
  • 11. Kaniusas E, Szeles JC, Kampusch S, et al. Non-invasive auricular vagus nerve stimulation as a potential treatment for COVID19-Originated acute respiratory distress syndrome. Front Physiol. 2020;11:890.
  • 12. Kirchner A, Landis BN, Haslbeck M, et al. Chemosensory function in patients with vagal nerve stimulators. J Clin Neurophysiol. 2004;21:418-25.
Yıl 2023, Cilt: 5 Sayı: 3, 655 - 8, 18.09.2023
https://doi.org/10.37990/medr.1262924

Öz

Proje Numarası

-

Kaynakça

  • 1. Umakanthan S, Sahu P, Ranade A V, et al. Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Postgrad Med JPostgrad Med J. 2020;96:753- 8.
  • 2. Najafloo R, Majidi J, Asghari A, et al. Mechanism of anosmia caused by symptoms of COVID-19 and emerging treatments. ACS Chem Neurosci. 2021;12:3795-805.
  • 3. Khani E, Khiali S, Beheshtirouy S, Entezari-Maleki T. Potential pharmacologic treatments for COVID-19 smell and taste loss: a comprehensive review. Eur J Pharmacol. 2021;912:174582.
  • 4. Cain WS, Goodspeed RB, Gent JF, et al. Evaluation of olfactory dysfunction in the Connecticut chemosensory clinical research center. The Laryngoscope. 1998;98:83-8.
  • 5. Veyseller B, Ozucer B, Karaaltin AB, et al. Connecticut (CCCRC) olfactory test: normative values in 426 healthy volunteers. Indian J Otolaryngol Head Neck Surg. 2014;66:31-4.
  • 6. Sperling W, Biermann T, Spannenberger R, et al. Changes in gustatory perceptions of patients with major depression treated with vagus nerve stimulation (VNS). Pharmacopsychiatry. 2011;44:67–71.
  • 7. Whitcroft KL, Hummel T. Olfactory Dysfunction in COVID-19: diagnosis and management. JAMA. 2020;323:2512-4.
  • 8. Haehner A, Draf J, Dräger S, De With K, Hummel T. Predictive value of sudden olfactory loss in the diagnosis of COVID-19. ORL. 2020;82:175–80.
  • 9. Moein ST, Hashemian SMR, Mansourafshar B, et al. Smell dysfunction: a biomarker for COVID-19. Int Forum Allergy Rhinol. 2020;10:944-50.
  • 10. Mueller C, Temmel AFP, Quint C, Rieger A, Hummel T. Olfactory function in HIV-positive subjects. Acta Otolaryngol. 2002;122:67-71.
  • 11. Kaniusas E, Szeles JC, Kampusch S, et al. Non-invasive auricular vagus nerve stimulation as a potential treatment for COVID19-Originated acute respiratory distress syndrome. Front Physiol. 2020;11:890.
  • 12. Kirchner A, Landis BN, Haslbeck M, et al. Chemosensory function in patients with vagal nerve stimulators. J Clin Neurophysiol. 2004;21:418-25.
Toplam 12 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Vaka Takdimi
Yazarlar

Berkay Eren Pehlivanoğlu 0000-0002-1182-6161

Sanem Güven 0000-0001-8096-8748

Sefa Haktan Hatık 0000-0003-0517-4600

Ali Veysel Özden 0000-0003-2349-996X

Proje Numarası -
Erken Görünüm Tarihi 14 Temmuz 2023
Yayımlanma Tarihi 18 Eylül 2023
Kabul Tarihi 9 Haziran 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 5 Sayı: 3

Kaynak Göster

AMA Pehlivanoğlu BE, Güven S, Hatık SH, Özden AV. The Effect of Vagus Nerve Stimulation Applications on Taste and Smell Loss in COVID-19 Syndrome: Case Report. Med Records. Eylül 2023;5(3):655-8. doi:10.37990/medr.1262924

 Chief Editors

Assoc. Prof. Zülal Öner
Address: İzmir Bakırçay University, Department of Anatomy, İzmir, Turkey

Assoc. Prof. Deniz Şenol
Address: Düzce University, Department of Anatomy, Düzce, Turkey

E-mail: medrecsjournal@gmail.com

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