Aim: Our retrospective study was designed to explore the potential link between Helicobacter pylori (H. pylori) infection and the occurrence of colorectal cancer (CRC), gastric atrophy, and intestinal metaplasia.
Material and Methods: We assembled two groups of 150 patients each, categorized based on their endoscopic biopsy results for H. pylori - one group testing positive (study group), the other negative (control group). All subjects underwent upper and lower gastrointestinal endoscopies, and we assessed their endoscopic gastric biopsy results as well as any indications of colorectal malignancies.
Results: Our investigation established a noteworthy association between the presence of H. pylori infection and the incidences of CRC, gastric atrophy, and intestinal metaplasia (p<0.05). Our data suggests that individuals testing positive for H. pylori faced a 64% greater likelihood of developing CRC compared to those who tested negative. Among patients diagnosed with gastric atrophy, a remarkable 73.9% tested positive for H. pylori. Similarly, 78.9% of patients with intestinal metaplasia were also H. pylori positive.
Conclusion: Our results underscore a meaningful correlation between H. pylori infection and a heightened incidence of CRC, gastric atrophy, and intestinal metaplasia. Further, prospective studies will be instrumental in deciphering the underlying causative mechanisms and assessing the feasibility of H. pylori eradication as a preventive measure against these conditions.
Helicobacter pylori colorectal cancer gastric atrophy intestinal metaplasia endoscopic biopsy
YOK
-
-
-
Birincil Dil | İngilizce |
---|---|
Konular | Gastroenteroloji Cerrahisi, Genel Cerrahi, Gastroenteroloji ve Hepatoloji |
Bölüm | Özgün Makaleler |
Yazarlar | |
Proje Numarası | - |
Yayımlanma Tarihi | 19 Ekim 2023 |
Kabul Tarihi | 22 Ağustos 2023 |
Yayımlandığı Sayı | Yıl 2023 Cilt: 5 Sayı: Supplement (1) - Innovations in Medicine and Healthcare in the 100th Year of the Republic |
Chief Editors
Assoc. Prof. Zülal Öner
Address: İzmir Bakırçay University, Department of Anatomy, İzmir, Turkey
Assoc. Prof. Deniz Şenol
Address: Düzce University, Department of Anatomy, Düzce, Turkey
E-mail: medrecsjournal@gmail.com
Publisher:
Medical Records Association (Tıbbi Kayıtlar Derneği)
Address: Orhangazi Neighborhood, 440th Street,
Green Life Complex, Block B, Floor 3, No. 69
Düzce, Türkiye
Web: www.tibbikayitlar.org.tr
Publication Support:
Effect Publishing & Agency
Phone: + 90 (540) 035 44 35
E-mail: info@effectpublishing.com
Address: Akdeniz Neighborhood, Şehit Fethi Bey Street,
No: 66/B, Ground floor, 35210 Konak/İzmir, Türkiye
web: www.effectpublishing.com