The effect of royal jelly supplementation for three months on bone markers in postmenopausal osteoporotic women

Yıl 2021, Cilt: 21 Sayı: 1, 59 - 68, 15.07.2021

Bünyamin Aydın , Müge Atar , Özgür Pirgon

Öz

Bu çalışmada postmenopozal dönemdeki osteoporozu olan kadınlarda 3 aylık arı sütü (royal jelly) kullanımının kemik yapım ve yıkım belirteçlerini değerlendirerek kemik üzerindeki etkilerinin değerlendirilmesi amaçlanmıştır. Postmenopozal seksen kadın katılımcı, rastgele olarak arısütü verilenler (n=50)ve verilmeyenler (n=30) olarak ikiye ayrılmıştır. Arısütü alan gruba üç ay boyunca içerisinde 1 gram arısütü olan 100 mL sıvı verilmiştir. Kontrol grubuna ise yine 100 mL sıvı olacak şekilde plasebo verilmiştir. Kemik yapım belirteci olan N-terminal propeptit tip 1 kollajen (P1NP) ve kemik yıkım belirteci olan C-terminal telopeptit tip1 kollajen (CTX), sklerostin seviyeleri 0. ve 3. Ayda olmak üzere her iki grupta incelenmiştir. Sonuç olarak yaş, menopoz süresi, vücut kitle indeksi ve lomber vertebra kemik mineral dansitometri T skoru açısından benzer iki grupta kemik yapım ve yıkım beliteçleri açısından fark saptanmamıştır. Östrojenik etkisi yüksek olan arı sütünün 3 aylık süre boyunca kullanımı ile osteoporoz üzerine etkisi gösterilememiştir.

Anahtar Kelimeler

Arı sütü, osteoporoz, postmenopoz, östrojen

Proje Numarası

4424

Kaynakça

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