Varenicline-induced manic episode

Abstract

Varenicline is a novel antismoking agent that reduces cravings and blocks pleasure of nicotine by serving as a partial agonist to the nicotinic receptor. Varenicline has been associated with some important psychiatric adverse effects in patients with psychiatric history. However, varenicline related manic episode has not been reported so far in the literature in patients with no psychiatric history. Here we report a manic episode case with psychotic features developed in an individual on varenicline with no personal and family psychiatric history.

Keywords

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Varenikline bağlı manik dönem

Öz

Vareniklin, nikotinik reseptörlerde kısmi agonist etki göstererek nikotin isteğini bloke eden ve aşermeyi azaltan yeni bir antismoking (sigara içme karşıtı) ilaçtır. Psikiyatrik öyküsü olan hastalarda bazı önemli olumsuz psikiyatrik etkilerle ilişkilendirilir. Bugüne kadar, psikiyatrik öyküsü olmayan hastalarda varenikline bağlı manik dönem bildirilmemiştir. Bu yayında ilk kez, ailesinde ve kendisinde psikiyatrik hastalık öyküsü olmayan bir bireyde, varenikline bağlı psikotik bulgulu manik dönem tanımlanmaktadır.

Anahtar Kelimeler

• variniklin, mani, nikotin

Kaynakça

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