BibTex RIS Kaynak Göster

Quality of life in multiple sclerosis patients: impact of depression and physical limitations?

Yıl 2011, , 63 - 7, 01.02.2011
https://doi.org/10.5455/jmood.20110419054303

Öz

Aim: Quality of life (QOL) may be effected by disability. The aim of the present paper was to evaluate the depression which was common and treatable burden of multiple sclerosis (MS) and the effect of depression on quality of life. Method: Depression was evaluated in 62 MS patients. Data on health-related QOL (SF-36) was obtained in all MS patients. The results were compared to 24 ages and sex matched healthy controls. Disease related QOL and effects of depression, disability, and disease duration on QOL were evaluated in MS cases. Results: In the present study, 34% of the patients (n: 20) and 12.5% of the controls (n: 3) had depression (p<0.01). Sub scores of SF-36 mostly were lower statistically in patients (p<0.05). We found that there was a negative correlation between Beck depression scores and SF-36 sub scores (p<0.01). Functional limitations (disability scores) and disease duration was not related to SF-36 sub scores in statistical analysis. Conclusions: The presence of depression was found as a factor effecting QOL in comparison to disability or disease duration. It was concluded that evaluation and treatment of depression was important factor effecting QOL in follow-up of MS patients.

Kaynakça

  • Hastings D. Adjustment, coping resources, and care of the patient with multiple sclerosis. In Miller JF (editor). Coping with Chronic Illness, Overcoming Powerlessness. 2nd ed., Philadelphia: FA Davis, 1992: p. 222–54.
  • Rothwell PM, McDowel JD, Wong CK, Dorman PJ. Doctors and patients don’t agree: cross sectional study of patients’ and doctors’ perceptions and assessments of disability in multiple sclerosis. BMJ. 1997;314:1580– 83.
  • Pittion-Vouyovitch S, Debouverie M, Guillemin F, Vandenberghe N, Anxionnat R, Vespignani H. Fatigue in multiple sclerosis is related to disability, depression and quality of life. Journal of the Neurological Sciences. 2006;243:39-45.
  • D’alisa S, Miscio G, Baudo S, Simone A, Tesio L, Mauroi A. Depression is the main determinant of quality of life in multiple sclerosis: A classiŞcation-regression (CART) study. Disability and Rehabilitation. 2006;28:307-14.
  • Poser C, Paty D, Scheinberg L, McDonald W, David F, Ebers G, ve ark. New diagnostic criteria for multiple sclerosis: Guidelines for research protocols. Ann Neurol. 1983;13: 227-31.
  • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983;33:1444– 52.
  • Koçyiğit H, Aydemir Ö, Ölmez N, Memiş A. Kısa Form-36 (KF-36)’nın Türkçe Versiyonunun Güvenilirliği ve Geçerliliği. İlaç ve Tedavi Dergisi. 1999;12:102-106.
  • Hisli N. Beck Depresyon Envanteri’nin geçerliği üzerine bir çalışma. Türk Psikoloji Dergisi. 1988;6:118-126.
  • Brazier JE, Harper R, Jones NM, O’Cathain A, Thomas KJ, Usherwood T, Westlake L. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305:160-4.
  • Pati F, Cacopardo M, Palermo F, Ciancio MR, Lopes R, Restivo D, Reggio A. Health-related quality of life and depression in an Italian sample of multiple sclerosis patients. Journal of the Neurological Sciences. 2003;211:55–62.
  • McHorney CA, Ware JJ, Raczek AE. The MOS 36-Item Short- Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Medical Care. 1993;31:247-63.
  • Janssens ..Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners. Acta Neurol Scand. 2003;108:389–395.
  • Hakim EA, Bakheit AM, Bryant TN et al. The social impact of multiple sclerosis – a study of 305 patients and their relatives. Disabil Rehabil. 2000;22:288–93.
  • Solari A, Radice D. Health status of people with multiple sclerosis: a community mail survey. Neurol Sci. 2001;22:307–15.
  • Nortvedt MW, Riise T, Myhr KM, Nyland HI. Quality of life in multiple sclerosis: measuring the disease effects more broadly. Neurology. 1999;53:1098–103.
  • The Canadian Burden of Illness Study Group. Burden of illness of multiple sclerosis: Part II: Quality of life. Can J Neurol Sci. 1998;25:31–8.
  • D’alisa S, Miscio G, Baudo S, Simone A, Tesio L, Mauroi A. Depression is the main determinant of quality of life in multiple sclerosis: A classiŞcation-regression (CART) study. Disability and Rehabilitation. 2006;28:307-14.
  • Fruewald S, Loeer-Stastka H, Eher R, Saletu B, Baumhacki U. Depression and quality of life in multiple sclerosis. Acta Neurol Scand. 2001;104:257–61.
  • Kroencke DC, Denney DR, Lynch SG. Depression during exacerbations in multiple sclerosis: the importance of uncertainty. Mult Scler. 2001;7:237–42.
  • Solari A, Filippini G, Mendozzi L, Ghezzi A, Cifani S, Barbieri E, et al. Validation of Italian multiple sclerosis quality of life 54 questionnaire. J Neurol Neurosurg Psychiatry. 1999;67:158-62.
  • Fruehwald S, Loeffler-Stastka H, Eher R, Saletu B, Baumhackl U. Depression and Quality of life in multiple sclerosis. Acta Neurol Scand. 2001;104:257-61.

Multipl skleroz olgularında yaşam kalitesi: Fiziksel özürlülük ve depresyonun etkisi?

Yıl 2011, , 63 - 7, 01.02.2011
https://doi.org/10.5455/jmood.20110419054303

Öz

Amaç: Sağlıkla ilişkili yaşam kalitesi (YK) fiziksel özürlülüğe bağlı olarak etkilenir. Bu çalışmanın amacı multipl skleroz’un (MS) yaygın ve tedavi edilebilir bir boyutu olan depresyonun YK üzerine etkilerini ortaya koymaktır. Yöntem: Takipte olan 62 MS hastası, depresyon varlığı açısından değerlendirildi. Çalışmaya alınan tüm MS olguları için SF-36 YK ölçeği skoru hesaplandı. Yaş ve cinsiyet açısından benzer 24 sağlıklı kontrole ait depresyon ve YK ölçekleri sonuçlarıyla karşılaştırıldı. MS olgularında depresyonun, fiziksel özürlülüğün ve hastalık sürecinin YK üzerine etkileri araştırıldı. Bulgular: MS hastalarının %32.3 (n:20)’nde depresyon saptanırken, kontrol hastalarının yalnızca %12.5 (n:3)’nde depresyon saptandı (p<0.01). SF-36 ölçeği alt skorlarının birçoğunda da MS hastalarına ait skorlar kontrollere kıyasla istatistiksel olarak anlamlılık ifade edecek biçimde düşük bulundu (p<0.05). İlişki (korelasyon) analizleri sonrasında Beck depresyon skorları ve SF-36 alt ölçeklerinin tümüne ait skorlar arasında istatistiksel olarak anlamlı negatif bir ilişki bulundu (p<0.01). Fiziksel özürlülük ve hastalık süreci ile SF-36 alt ölçekleri skorlarının hiçbirisi arasında istatistiksel olarak anlamlı bir ilişki bulunamadı. Tartışma ve Sonuç: Fiziksel özürlülük veya hastalık sürecinden daha çok depresyonun varlığı YK’yı etkileyen bir etmen olarak bulundu. MS hastalarının takibinde depresyonun tespiti ve tedavisinin YK’ye katkısının önemli olduğu sonucuna varıldı.

Kaynakça

  • Hastings D. Adjustment, coping resources, and care of the patient with multiple sclerosis. In Miller JF (editor). Coping with Chronic Illness, Overcoming Powerlessness. 2nd ed., Philadelphia: FA Davis, 1992: p. 222–54.
  • Rothwell PM, McDowel JD, Wong CK, Dorman PJ. Doctors and patients don’t agree: cross sectional study of patients’ and doctors’ perceptions and assessments of disability in multiple sclerosis. BMJ. 1997;314:1580– 83.
  • Pittion-Vouyovitch S, Debouverie M, Guillemin F, Vandenberghe N, Anxionnat R, Vespignani H. Fatigue in multiple sclerosis is related to disability, depression and quality of life. Journal of the Neurological Sciences. 2006;243:39-45.
  • D’alisa S, Miscio G, Baudo S, Simone A, Tesio L, Mauroi A. Depression is the main determinant of quality of life in multiple sclerosis: A classiŞcation-regression (CART) study. Disability and Rehabilitation. 2006;28:307-14.
  • Poser C, Paty D, Scheinberg L, McDonald W, David F, Ebers G, ve ark. New diagnostic criteria for multiple sclerosis: Guidelines for research protocols. Ann Neurol. 1983;13: 227-31.
  • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 1983;33:1444– 52.
  • Koçyiğit H, Aydemir Ö, Ölmez N, Memiş A. Kısa Form-36 (KF-36)’nın Türkçe Versiyonunun Güvenilirliği ve Geçerliliği. İlaç ve Tedavi Dergisi. 1999;12:102-106.
  • Hisli N. Beck Depresyon Envanteri’nin geçerliği üzerine bir çalışma. Türk Psikoloji Dergisi. 1988;6:118-126.
  • Brazier JE, Harper R, Jones NM, O’Cathain A, Thomas KJ, Usherwood T, Westlake L. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305:160-4.
  • Pati F, Cacopardo M, Palermo F, Ciancio MR, Lopes R, Restivo D, Reggio A. Health-related quality of life and depression in an Italian sample of multiple sclerosis patients. Journal of the Neurological Sciences. 2003;211:55–62.
  • McHorney CA, Ware JJ, Raczek AE. The MOS 36-Item Short- Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Medical Care. 1993;31:247-63.
  • Janssens ..Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of patients and partners. Acta Neurol Scand. 2003;108:389–395.
  • Hakim EA, Bakheit AM, Bryant TN et al. The social impact of multiple sclerosis – a study of 305 patients and their relatives. Disabil Rehabil. 2000;22:288–93.
  • Solari A, Radice D. Health status of people with multiple sclerosis: a community mail survey. Neurol Sci. 2001;22:307–15.
  • Nortvedt MW, Riise T, Myhr KM, Nyland HI. Quality of life in multiple sclerosis: measuring the disease effects more broadly. Neurology. 1999;53:1098–103.
  • The Canadian Burden of Illness Study Group. Burden of illness of multiple sclerosis: Part II: Quality of life. Can J Neurol Sci. 1998;25:31–8.
  • D’alisa S, Miscio G, Baudo S, Simone A, Tesio L, Mauroi A. Depression is the main determinant of quality of life in multiple sclerosis: A classiŞcation-regression (CART) study. Disability and Rehabilitation. 2006;28:307-14.
  • Fruewald S, Loeer-Stastka H, Eher R, Saletu B, Baumhacki U. Depression and quality of life in multiple sclerosis. Acta Neurol Scand. 2001;104:257–61.
  • Kroencke DC, Denney DR, Lynch SG. Depression during exacerbations in multiple sclerosis: the importance of uncertainty. Mult Scler. 2001;7:237–42.
  • Solari A, Filippini G, Mendozzi L, Ghezzi A, Cifani S, Barbieri E, et al. Validation of Italian multiple sclerosis quality of life 54 questionnaire. J Neurol Neurosurg Psychiatry. 1999;67:158-62.
  • Fruehwald S, Loeffler-Stastka H, Eher R, Saletu B, Baumhackl U. Depression and Quality of life in multiple sclerosis. Acta Neurol Scand. 2001;104:257-61.
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Ülkü Türk Börü Bu kişi benim

Yayımlanma Tarihi 1 Şubat 2011
Yayımlandığı Sayı Yıl 2011

Kaynak Göster

APA Börü, Ü. T. (2011). Multipl skleroz olgularında yaşam kalitesi: Fiziksel özürlülük ve depresyonun etkisi?. Journal of Mood Disorders, 1(2), 63-7. https://doi.org/10.5455/jmood.20110419054303
AMA Börü ÜT. Multipl skleroz olgularında yaşam kalitesi: Fiziksel özürlülük ve depresyonun etkisi?. Journal of Mood Disorders. Şubat 2011;1(2):63-7. doi:10.5455/jmood.20110419054303
Chicago Börü, Ülkü Türk. “Multipl Skleroz olgularında yaşam Kalitesi: Fiziksel özürlülük Ve Depresyonun Etkisi?”. Journal of Mood Disorders 1, sy. 2 (Şubat 2011): 63-7. https://doi.org/10.5455/jmood.20110419054303.
EndNote Börü ÜT (01 Şubat 2011) Multipl skleroz olgularında yaşam kalitesi: Fiziksel özürlülük ve depresyonun etkisi?. Journal of Mood Disorders 1 2 63–7.
IEEE Ü. T. Börü, “Multipl skleroz olgularında yaşam kalitesi: Fiziksel özürlülük ve depresyonun etkisi?”, Journal of Mood Disorders, c. 1, sy. 2, ss. 63–7, 2011, doi: 10.5455/jmood.20110419054303.
ISNAD Börü, Ülkü Türk. “Multipl Skleroz olgularında yaşam Kalitesi: Fiziksel özürlülük Ve Depresyonun Etkisi?”. Journal of Mood Disorders 1/2 (Şubat 2011), 63-7. https://doi.org/10.5455/jmood.20110419054303.
JAMA Börü ÜT. Multipl skleroz olgularında yaşam kalitesi: Fiziksel özürlülük ve depresyonun etkisi?. Journal of Mood Disorders. 2011;1:63–7.
MLA Börü, Ülkü Türk. “Multipl Skleroz olgularında yaşam Kalitesi: Fiziksel özürlülük Ve Depresyonun Etkisi?”. Journal of Mood Disorders, c. 1, sy. 2, 2011, ss. 63-7, doi:10.5455/jmood.20110419054303.
Vancouver Börü ÜT. Multipl skleroz olgularında yaşam kalitesi: Fiziksel özürlülük ve depresyonun etkisi?. Journal of Mood Disorders. 2011;1(2):63-7.