BibTex RIS Kaynak Göster

Comorbid bipolar disorder among patients with conversion disorder

Yıl 2013, Cilt: 3 Sayı: 2, 58 - 63, 01.02.2013
https://doi.org/10.5455/jmood.20130116052209

Öz

Background: Psychiatric comorbidity rate among the patients with conversion disorder was reported between 31-71%. The present study was planned to assess the overall psychiatric comorbidity, particularly bipolar disorder comorbidity in patients with conversion disorder. Methods: A total of 100 consecutive patients admitted to the Psychiatric Emergency Unit of Sisli Etfal Teaching and Research Hospital in Istanbul, Turkey from April 2006 to November 2006 and diagnosed with conversion disorder were included in this study. SCID-I and sociodemographical form were administered to the patients. Results: Bipolar disorder was found in 28% of the patients. The rate of dissociative disorder not otherwise specified (NOS), panic disorder, eating disorder comorbidity were higher in conversion disorder patients with bipolar disorder. In comparison with unipolar patients, bipolar patients had significantly lower Global Assessment of Functioning scores (p=0.03). Conclusion: It is important to determine comorbidity and previous psychiatric history in patients with conversion disorder. If there is comorbid bipolar disorder, clinicians should consider mood stabilizing agents, and avoid antidepressants in the treatment of conversion disorder. Apart from other studies on conversion disorder, this study assessed comorbid bipolar disorder and other axis I diagnoses in patients with conversion disorder for the first time.

Kaynakça

  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4 th edition, American Psychiatric Association, Washington D.C, 2004.
  • Sar V, Akyuz G, Kundakci T, Kiziltan E, Dogan O. Childhood trauma, dissociation, and psychiatric comorbidity in patients with conversion disorder. Am J Psychiatry. 2004:161;2271-6.
  • Guz H, Doganay Z, Guven H, Ozcan A. A retrospective evaluation of the psychiatric consultations which were requested by the emergency department. Turkish Journal of Emergency Medicine. 2003: Tomasson K, Kent D, Coryell W. Somatization and conversion disorders: comorbidity and demographics at presentation. Acta Psychiatr Scand. 1991;84:288-93.
  • Lempert T, Schmidt D. Natural history and outcome of psychogenic seizures: a clinical in 50 patients. J Neurology. 1990;237:35-8.
  • Walczack TS, Papacostas S, Williams DT, Scheurer MI, Lebowitz N, Notarfrancesco A. Outcome after diagnosis of pschogenic nonepileptic seizures. Epilepsia. 1995;36:1131-7.
  • Arnold LM, Privitera MD. Psychopathology and trauma in epileptic and psychogenic seizure patients. Psychosomatics. 1996;37:438
  • Roy A. Pseudoseizures: a psychiatric perspective. J Neuropsychiatr Clin Neurosci. 1989;1:69-71.
  • Dunner D. Current psychiatric therapy. Philadelphia: WB Saunders, 1993;314-20.
  • Lesser RP. Psychogenic seizures. Neurology. 1996.46;1499-507.
  • Uguz S, Toros F. Sociodemographic and clinical characteristics of patients with conversion disorder. Turk J Psychiatry. 2003:14;51-8.
  • Corapcıoglu A, Aydemir O, Yildiz M, Esen A, Koroglu E. DSM-IV Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinical Version (Turkish Version). Hekimler Yayın Birligi, 1999, Ankara.
  • Stonnington CM, Barry JJ, Fisher RS. Conversion disorder. Am J Psychiatry. 2006;163:1510-7.
  • Green MJ, Cahill CM, Malhi GS. The cognitive and neoruphysiological basis of emotion dysregulation in bipolar disorder. J Affect Disord. 2007:103;29-42.
  • McLean PD. The triune brain in evolution: Role in paleocerebral functions. Plenum Pres, New York, 1990.
  • Vuilleumier P, Chicherio C, Assal F, Schwartz S, Slosman D, Landis T. Functional neuroanatomical correlates of hysterical sensorimotor loss. Brain. 2001:124;1077-90.
  • Black DN, Seritan AL, Taber KH, Hurley RA. Conversion hysteria: lessons from functional imaging: J Neuropsychiatry Clin Neurosci. 2004:6;245-51.
  • Spence SA, Crimlisk HL, Cope H,Ron MA, Grasby PM. Discrete neurophysiological correlates in prefrontal cortex during hysterical and feigned disorder of movement. Lancet. 2000:355;1243-4.
  • Marchand WR, Lee JN, Thatcher J, Thatcher GW, Jensen C, Starr J. A preliminary longitudinal fMRI study of frontal-subcortical circuits in bipolar disorder using a paced motor activation paradigm. J Affect Disord. 2007:103:237-41.
  • Strakowski SM, DelBello MP, Adler C. The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings. Molecular Psychiatry. 2005:10;105-16.
  • Binzer M, Anderson PM, Kullgren G. Clinical characteristics of patients with motor disability due to conversion disorder: a prospective control group study. J Neurol Neurosurg Psychiatr. 1997:63;83-8.
  • Hafeiz HB. Clinical aspects of hysteria. Acta Psychiatr Scand 1985:73;676-80.
  • Eisendrath, Stuart J. “Psychiatric Disorders.” In Current Medical Diagnosis and Treatment, edited by Stephen McPhee, et al., 37 th ed. Stamford: Appleton &Amp; Lange, 1997.
  • Goodyer IM. Hysterical conversions reactions in childhood. J Child Psychol Psychiatry. 1981:22;179-88.
  • Kuloglu M, Atmaca M, Tezcan E, Gecici O, Bulut S. Sociodemographic and clinical characteristics of patients with conversion disorder in Eastern Turkey. Soc Psychiatr Psychiatr Epidemiol. 2003:38;88-93.
  • Dula DJ, DeNaples L. Emergency department presentation of patients with conversion disorder. Academic Emergency Medicine. 1995:2;120-3.
  • Mattoo SK, Gupta N, Lobana A, Bedi B. Mass family hysteria: A report from India. Psychiatry Clin Neurosci. 2000:56;643.
  • Bowman ES, Markand ON. Psychodynamics and psyhiatric diagnosis of pseudoseizure subjects. Am J Psychiatry. 2003:153;57-63.

Konversiyon bozukluğu hastalarında bipolar bozukluk komorbiditesi

Yıl 2013, Cilt: 3 Sayı: 2, 58 - 63, 01.02.2013
https://doi.org/10.5455/jmood.20130116052209

Öz

Giriş: Konversiyon bozukluğu hastalarında psikiyatrik ekhastalık sıklığı %31-%71 arasında bildirilmiştir. Bu çalışmada konversiyon bozukluğu hastalarında başta iki uçlu bozukluk olmak üzere psikiyatrik ekhastalıkların değerendirilmesi planlanmıştır. Yöntem: Nisan 2006 ile Kasım 2006 arasında Şişli Etfal Eğitim ve Araştırma Hastanesi acil psikiyatri bölümüne başvuran ve konversiyon bozukluğu tanısı konulan 100 ardışık hasta çalışmaya dahil edildi. Hastalara SCID-I uygulandı ve sosyodemografik form dolduruldu. Bulgular: Hastaların %28’inde iki uçlu bozukluk saptandı. Başka türlü sınıflandırılamamış dissosiyatif bozukluk, panik bozukluk ve yeme bozukluğu ekhastalığı iki uçlu bozukluğu olan konversiyon hastalarında daha yüksek bulundu. Tek uçlu hastalara göre iki uçlu bozukluğu olan hastalarda anlamlı düzeyde düşük işevselliğin genel değerlendirilmesi skorları saptandı (p=0,03). Sonuç: Konversiyon bozukluğu hastalarında psikiyatrik öykü ve ekhastalığı belirlemek önemlidir. İki uçlu bozukluk ekhastalığı varsa klinisyenin konversiyon bozukluğu hastalarında antidepresan tedaviden kaçınmayı ve duygudurum dengeleyici eklemeyi gözönünde bulundurması gerekir. Diğer konversiyon bozukluğu çalışmalarından farklı olarak bu çalışmada yeni tanı konulmuş konversiyon bozukluğu hastalarında iki uçlu bozukluk ve diğer eksen I tanılarının ekhastalığı değerlendirilmiştir.

Kaynakça

  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4 th edition, American Psychiatric Association, Washington D.C, 2004.
  • Sar V, Akyuz G, Kundakci T, Kiziltan E, Dogan O. Childhood trauma, dissociation, and psychiatric comorbidity in patients with conversion disorder. Am J Psychiatry. 2004:161;2271-6.
  • Guz H, Doganay Z, Guven H, Ozcan A. A retrospective evaluation of the psychiatric consultations which were requested by the emergency department. Turkish Journal of Emergency Medicine. 2003: Tomasson K, Kent D, Coryell W. Somatization and conversion disorders: comorbidity and demographics at presentation. Acta Psychiatr Scand. 1991;84:288-93.
  • Lempert T, Schmidt D. Natural history and outcome of psychogenic seizures: a clinical in 50 patients. J Neurology. 1990;237:35-8.
  • Walczack TS, Papacostas S, Williams DT, Scheurer MI, Lebowitz N, Notarfrancesco A. Outcome after diagnosis of pschogenic nonepileptic seizures. Epilepsia. 1995;36:1131-7.
  • Arnold LM, Privitera MD. Psychopathology and trauma in epileptic and psychogenic seizure patients. Psychosomatics. 1996;37:438
  • Roy A. Pseudoseizures: a psychiatric perspective. J Neuropsychiatr Clin Neurosci. 1989;1:69-71.
  • Dunner D. Current psychiatric therapy. Philadelphia: WB Saunders, 1993;314-20.
  • Lesser RP. Psychogenic seizures. Neurology. 1996.46;1499-507.
  • Uguz S, Toros F. Sociodemographic and clinical characteristics of patients with conversion disorder. Turk J Psychiatry. 2003:14;51-8.
  • Corapcıoglu A, Aydemir O, Yildiz M, Esen A, Koroglu E. DSM-IV Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinical Version (Turkish Version). Hekimler Yayın Birligi, 1999, Ankara.
  • Stonnington CM, Barry JJ, Fisher RS. Conversion disorder. Am J Psychiatry. 2006;163:1510-7.
  • Green MJ, Cahill CM, Malhi GS. The cognitive and neoruphysiological basis of emotion dysregulation in bipolar disorder. J Affect Disord. 2007:103;29-42.
  • McLean PD. The triune brain in evolution: Role in paleocerebral functions. Plenum Pres, New York, 1990.
  • Vuilleumier P, Chicherio C, Assal F, Schwartz S, Slosman D, Landis T. Functional neuroanatomical correlates of hysterical sensorimotor loss. Brain. 2001:124;1077-90.
  • Black DN, Seritan AL, Taber KH, Hurley RA. Conversion hysteria: lessons from functional imaging: J Neuropsychiatry Clin Neurosci. 2004:6;245-51.
  • Spence SA, Crimlisk HL, Cope H,Ron MA, Grasby PM. Discrete neurophysiological correlates in prefrontal cortex during hysterical and feigned disorder of movement. Lancet. 2000:355;1243-4.
  • Marchand WR, Lee JN, Thatcher J, Thatcher GW, Jensen C, Starr J. A preliminary longitudinal fMRI study of frontal-subcortical circuits in bipolar disorder using a paced motor activation paradigm. J Affect Disord. 2007:103:237-41.
  • Strakowski SM, DelBello MP, Adler C. The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings. Molecular Psychiatry. 2005:10;105-16.
  • Binzer M, Anderson PM, Kullgren G. Clinical characteristics of patients with motor disability due to conversion disorder: a prospective control group study. J Neurol Neurosurg Psychiatr. 1997:63;83-8.
  • Hafeiz HB. Clinical aspects of hysteria. Acta Psychiatr Scand 1985:73;676-80.
  • Eisendrath, Stuart J. “Psychiatric Disorders.” In Current Medical Diagnosis and Treatment, edited by Stephen McPhee, et al., 37 th ed. Stamford: Appleton &Amp; Lange, 1997.
  • Goodyer IM. Hysterical conversions reactions in childhood. J Child Psychol Psychiatry. 1981:22;179-88.
  • Kuloglu M, Atmaca M, Tezcan E, Gecici O, Bulut S. Sociodemographic and clinical characteristics of patients with conversion disorder in Eastern Turkey. Soc Psychiatr Psychiatr Epidemiol. 2003:38;88-93.
  • Dula DJ, DeNaples L. Emergency department presentation of patients with conversion disorder. Academic Emergency Medicine. 1995:2;120-3.
  • Mattoo SK, Gupta N, Lobana A, Bedi B. Mass family hysteria: A report from India. Psychiatry Clin Neurosci. 2000:56;643.
  • Bowman ES, Markand ON. Psychodynamics and psyhiatric diagnosis of pseudoseizure subjects. Am J Psychiatry. 2003:153;57-63.
Toplam 27 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Oguz K. Karamustafalıoğlu Bu kişi benim

Başak Özçelik Bu kişi benim

Sinem Gönenli Toker Bu kişi benim

Bahadır Bakım Bu kişi benim

Yasemin Cengiz Ceylan Bu kişi benim

Abdullah Akpınar Bu kişi benim

Uğraş Uzun Bu kişi benim

Onur Tankaya Bu kişi benim

Mehmet Çevik Bu kişi benim

Burcu Yavuz Bu kişi benim

Vahap Karabulut Bu kişi benim

Ebru Toprak Bu kişi benim

Yayımlanma Tarihi 1 Şubat 2013
Yayımlandığı Sayı Yıl 2013 Cilt: 3 Sayı: 2

Kaynak Göster

APA Karamustafalıoğlu, O. K., Özçelik, B., Toker, S. G., Bakım, B., vd. (2013). Konversiyon bozukluğu hastalarında bipolar bozukluk komorbiditesi. Journal of Mood Disorders, 3(2), 58-63. https://doi.org/10.5455/jmood.20130116052209
AMA Karamustafalıoğlu OK, Özçelik B, Toker SG, Bakım B, Ceylan YC, Akpınar A, Uzun U, Tankaya O, Çevik M, Yavuz B, Karabulut V, Toprak E. Konversiyon bozukluğu hastalarında bipolar bozukluk komorbiditesi. Journal of Mood Disorders. Şubat 2013;3(2):58-63. doi:10.5455/jmood.20130116052209
Chicago Karamustafalıoğlu, Oguz K., Başak Özçelik, Sinem Gönenli Toker, Bahadır Bakım, Yasemin Cengiz Ceylan, Abdullah Akpınar, Uğraş Uzun, Onur Tankaya, Mehmet Çevik, Burcu Yavuz, Vahap Karabulut, ve Ebru Toprak. “Konversiyon bozukluğu hastalarında Bipolar Bozukluk Komorbiditesi”. Journal of Mood Disorders 3, sy. 2 (Şubat 2013): 58-63. https://doi.org/10.5455/jmood.20130116052209.
EndNote Karamustafalıoğlu OK, Özçelik B, Toker SG, Bakım B, Ceylan YC, Akpınar A, Uzun U, Tankaya O, Çevik M, Yavuz B, Karabulut V, Toprak E (01 Şubat 2013) Konversiyon bozukluğu hastalarında bipolar bozukluk komorbiditesi. Journal of Mood Disorders 3 2 58–63.
IEEE O. K. Karamustafalıoğlu, “Konversiyon bozukluğu hastalarında bipolar bozukluk komorbiditesi”, Journal of Mood Disorders, c. 3, sy. 2, ss. 58–63, 2013, doi: 10.5455/jmood.20130116052209.
ISNAD Karamustafalıoğlu, Oguz K. vd. “Konversiyon bozukluğu hastalarında Bipolar Bozukluk Komorbiditesi”. Journal of Mood Disorders 3/2 (Şubat 2013), 58-63. https://doi.org/10.5455/jmood.20130116052209.
JAMA Karamustafalıoğlu OK, Özçelik B, Toker SG, Bakım B, Ceylan YC, Akpınar A, Uzun U, Tankaya O, Çevik M, Yavuz B, Karabulut V, Toprak E. Konversiyon bozukluğu hastalarında bipolar bozukluk komorbiditesi. Journal of Mood Disorders. 2013;3:58–63.
MLA Karamustafalıoğlu, Oguz K. vd. “Konversiyon bozukluğu hastalarında Bipolar Bozukluk Komorbiditesi”. Journal of Mood Disorders, c. 3, sy. 2, 2013, ss. 58-63, doi:10.5455/jmood.20130116052209.
Vancouver Karamustafalıoğlu OK, Özçelik B, Toker SG, Bakım B, Ceylan YC, Akpınar A, Uzun U, Tankaya O, Çevik M, Yavuz B, Karabulut V, Toprak E. Konversiyon bozukluğu hastalarında bipolar bozukluk komorbiditesi. Journal of Mood Disorders. 2013;3(2):58-63.