Treatment of COVID 19

Yıl 2020, Cilt: 3 Sayı: Özel Sayı, 17 - 31, 05.08.2020

Mustafa Uğuz , Burak Eşkut

Öz

COVID pandemiac, arised from China at 2019 December and affecting wide world nowadays, is a wide clinical spectrum from asymptomatic to serious pneumonia. Currently, treatment protocols are based on suggestions from guidelines and clinical trials, but already there is no spesific treatment or prophylaxis method. Nevertheless hydroxychloroquine and favipiravir are in use in our country by the guidence of Republic of Türkiye Ministry of Health COVID-19 Guidelines and found to be benefical . among pregnant patients lopinavir and ritonavir ar in use, instead of favipiravir. Recently publıshed data showed benefical effect of remdesivir. In management of COVID-19 no twith standing there is convinction that immune plasma is affective, there is lack of data. Recently, thrombosis , emerging among critical cases, revived antiaggregant treatment. Specific treatment searches are ongoing, and better planned scientific studies with larger number of cases are needed.

Anahtar Kelimeler

covid 19, hydroxychloroquine, SARS-CoV-2

Covid 19 Enfeksiyon tedavisi

Öz

Covid 19; 2019 yılı aralık ayında çin’in wuhan bölgesinden başlayarak bugün tüm dünyayı etkisi altına alarak pandemi boyutuna ulaşmıştır. Asemptomatik hastalıktan ; ağır pnomoni klinğine kadar ilerleyen geniş bir klinik yelpazeye sahiptir. Tedavi protokolleri halen rehber önerileri ve klinik çalışmalar ile sınırlıdır ve henüz kullanıma girmiş spesifik bir tedavi ve profilaksi yöntemi mevcut değildir. Uluslararası rehberlerde tedavi protokollerinde yer alan hidroksiklorokin ve favipiravir ülkemizde de T.C. Sağlık Bakanlığı COVID-19 rehberine göre tedavide kullanılmakta ve hastaların tedavisinde fayda sağlamaktadır. Gebelerde ise favipiravir kullanılamadığından lopinavir ve ritonavir kullanılmaktadır. Remdesivir, son zamanlarda COVID-19 için etkili olduğu çalışmalar mevcuttur. COVID-19 tedavisinde immün plazmanın da etkili olduğuna dair görüşler bulunsa da etkinliğine dair net bilimsel çalışmalar halen yetersizdir. Özellikle ileri evre olgularda komplikasyon olarak karşımıza çıkan tromboz antiagregan tedaviyi de gündeme getirmiştir. Spesifik tedavi arayışları devam etmekte ve daha iyi planlanmış geniş olgu sayılı bilimsel çalışmalara ihtiyaç duyulmaktadır

Anahtar Kelimeler

covid 19, Hidroksiklorokin, SARS-Cov-2

Kaynakça

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