Öz
The Ministry of Health in Turkey approved the use of pregabalin at 150-600 mg/day doses in peripheral neuropathic pain, generalized anxiety disorder, fibromyalgia and as adjunctive therapy in adult patients with partial epilepsy. Hair loss is rarely seen among psychotropic drugs. This side effect is most frequently reported in mood stabilizers among psychotropic agents. In this case, we aimed to present a case of common hair loss, which was not seen in the literature before, occurred after starting pregabalin treatment and resolved only by discontinuation of treatment.
Anahtar Kelimeler
Kaynakça
- 1. Stahl SM. Anticovulsants and relief of cranic pain: pregabalin anda gabapentin as alpha(2)delta ligands at voltage-gated calcıum channels. J Clin Psychiatry 2004;65:596-7.
- 2. Lauria-Horner BA, Pohl RB. Pregabalin: a new anxiolytic. Expert opin Investing Drugs 2003;12:663-72.
- 3. Orwin A: Hair loss following lithium therapy. Br J Dermatol 1983;108:503-4.
- 4. Öztürkcan S, Ateş M. Alopecia and drugs. Türkderm 2014; 48: Özel Sayı 1: 48-51.
- 5. Headington JT: Telogen effluvium. New concepts and review. Arch Dermatol 1993;129: 356–363.
- 6. Harrison S, Bergfeld W: Diffuse hair loss: its triggers and management. Cleve Clin J Med 2009;76:361-7.
- 7. Mansi Patel, Shannon Harrison, Rodney Sinclair: Drugs and Hair Loss. Dermatol Clin 2013;31:67-73.
- 8. Tosti A, Pazzaglia M: Drug reactions affecting hair: diagnosis. Dermatol Clin 2007;25:223-31.
- 9. Rais T, Singh T, Rais A: Hair loss associated with long-term sertraline treatment in teenager. Psychiatry 2005;2:52.
- 10. Kuloglu M, Korkmaz S, Kilid N: Olanzapine induced hair loss: a case report. Bulletin of Clinical Psychopharmacology 2012;22:362-5.
Öz
Türkiye’de Sağlık Bakanlığı pregabalinin periferik nöropatik ağrıda, yaygın anksiyete bozukluğunda, fibromiyaljide ve parsiyel epilepsili yetişkin hastalarda ek tedavi olarak 150–600 mg/gün dozunda kullanımını onaylamıştır. Saç dökülmesi psikotropik ilaçlar arasında nadiren görülür. Bu yan etki psikotropik ajanlar içinde en sık duygudurum düzenleyicilerde bildirilmektedir. Biz bu vakada daha önce literatürde bildirimine rastlamadığımız pregabalin tedavisine başladıktan sonra ortaya çıkan ve sadece tedavinin sonlandırılmasıyla düzelen, yaygın saç dökülmesi olan bir olguyu sunmayı amaçladık.
Anahtar Kelimeler
Kaynakça
- 1. Stahl SM. Anticovulsants and relief of cranic pain: pregabalin anda gabapentin as alpha(2)delta ligands at voltage-gated calcıum channels. J Clin Psychiatry 2004;65:596-7.
- 2. Lauria-Horner BA, Pohl RB. Pregabalin: a new anxiolytic. Expert opin Investing Drugs 2003;12:663-72.
- 3. Orwin A: Hair loss following lithium therapy. Br J Dermatol 1983;108:503-4.
- 4. Öztürkcan S, Ateş M. Alopecia and drugs. Türkderm 2014; 48: Özel Sayı 1: 48-51.
- 5. Headington JT: Telogen effluvium. New concepts and review. Arch Dermatol 1993;129: 356–363.
- 6. Harrison S, Bergfeld W: Diffuse hair loss: its triggers and management. Cleve Clin J Med 2009;76:361-7.
- 7. Mansi Patel, Shannon Harrison, Rodney Sinclair: Drugs and Hair Loss. Dermatol Clin 2013;31:67-73.
- 8. Tosti A, Pazzaglia M: Drug reactions affecting hair: diagnosis. Dermatol Clin 2007;25:223-31.
- 9. Rais T, Singh T, Rais A: Hair loss associated with long-term sertraline treatment in teenager. Psychiatry 2005;2:52.
- 10. Kuloglu M, Korkmaz S, Kilid N: Olanzapine induced hair loss: a case report. Bulletin of Clinical Psychopharmacology 2012;22:362-5.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Klinik Tıp Bilimleri |
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Aralık 2020 |
| Gönderilme Tarihi | 15 Ekim 2020 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 3 Sayı: 3 |