Diet induced weight loss reduces mean platelet volume in people with obesity

Cilt: 3 Sayı: 2 15 Şubat 2016
PDF İndir
EN TR

Diet induced weight loss reduces mean platelet volume in people with obesity

Abstract

Objectives: To investigate is there a relationship between obesity parameters, mean platelet volume (MPV) and neutrophil lymphocyte ratio (NLR), and to examine is there a change in MPV and NLR level with weight loss.

Material and Methods: The retrospective study consisted of two groups as the group losing weight after 24 weeks of diet (WLG) and the control group not losing weight (CG). Body mass index (BMI), MPV, NLR and lipid values of each group were recorded at the beginning and at the end of the study.

Results: The study consisted of 186 individuals 94 of whom were in WLG and 92 were in CG. There was a statistically significant positive correlation between the initial value of MPV and BMI in WLG (p <0.05). There was a significant difference existed in the initial and final lipid parameters of WLG (p<0.0001). Changes in initial and final MPV values in WLG and CG were different from each other (p <0.01). The difference between the initial and final MPV values and BMI values in WLG was statistically significant (P <0.001). No significant correlation was found between obesity and weight loss with NLR.

Conclusions: There was a statistically significant correlation between MPV and BMI. MPV levels decreased in obese individuals with weight loss. No correlation existed between BMI and NLR.

Keywords

Kaynakça

  1. Folsom AR, Aleksic N, Catellier D, Juneja HS, Wu KK. C-reactive protein and incident coronary heart disease in the Atherosclerosis Risk In Communities (ARIC) study. American heart journal. 2002;144(2):233-8.
  2. Folsom AR, Wu KK, Rosamond WD, Sharrett AR, Chambless LE. Prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation. 1997;96(4):1102-8.
  3. Adams KF, Schatzkin A, Harris TB, Kipnis V, Mouw T, Ballard-Barbash R, et al. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. The New England journal of medicine. 2006;355(8):763-78.
  4. Waxman A. Prevention of chronic diseases: WHO global strategy on diet, physical activity and health. Food and nutrition bulletin. 2003;24(3):281-4.
  5. Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2006;113(6):898-918.
  6. Elgazar-Carmon V, Rudich A, Hadad N, Levy R. Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. Journal of lipid research. 2008;49(9):1894-903.
  7. Pecht T, Gutman-Tirosh A, Bashan N, Rudich A. Peripheral blood leucocyte subclasses as potential biomarkers of adipose tissue inflammation and obesity subphenotypes in humans. Obesity reviews : an official journal of the International Association for the Study of Obesity. 2014;15(4):322-37.
  8. Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 1996;7(2):157-61.

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Davut Demirkiran Bu kişi benim

Yayımlanma Tarihi

15 Şubat 2016

Gönderilme Tarihi

11 Ocak 2016

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2016 Cilt: 3 Sayı: 2

Kaynak Göster

APA
Kurt, H., & Demirkiran, D. (2016). Diet induced weight loss reduces mean platelet volume in people with obesity. Medical Science and Discovery, 3(2), 98-102. https://doi.org/10.17546/msd.36399
AMA
1.Kurt H, Demirkiran D. Diet induced weight loss reduces mean platelet volume in people with obesity. Med Sci Discov. 2016;3(2):98-102. doi:10.17546/msd.36399
Chicago
Kurt, Huseyin, ve Davut Demirkiran. 2016. “Diet induced weight loss reduces mean platelet volume in people with obesity”. Medical Science and Discovery 3 (2): 98-102. https://doi.org/10.17546/msd.36399.
EndNote
Kurt H, Demirkiran D (01 Şubat 2016) Diet induced weight loss reduces mean platelet volume in people with obesity. Medical Science and Discovery 3 2 98–102.
IEEE
[1]H. Kurt ve D. Demirkiran, “Diet induced weight loss reduces mean platelet volume in people with obesity”, Med Sci Discov, c. 3, sy 2, ss. 98–102, Şub. 2016, doi: 10.17546/msd.36399.
ISNAD
Kurt, Huseyin - Demirkiran, Davut. “Diet induced weight loss reduces mean platelet volume in people with obesity”. Medical Science and Discovery 3/2 (01 Şubat 2016): 98-102. https://doi.org/10.17546/msd.36399.
JAMA
1.Kurt H, Demirkiran D. Diet induced weight loss reduces mean platelet volume in people with obesity. Med Sci Discov. 2016;3:98–102.
MLA
Kurt, Huseyin, ve Davut Demirkiran. “Diet induced weight loss reduces mean platelet volume in people with obesity”. Medical Science and Discovery, c. 3, sy 2, Şubat 2016, ss. 98-102, doi:10.17546/msd.36399.
Vancouver
1.Huseyin Kurt, Davut Demirkiran. Diet induced weight loss reduces mean platelet volume in people with obesity. Med Sci Discov. 01 Şubat 2016;3(2):98-102. doi:10.17546/msd.36399