Prevalance of early repolarization pattern in young healthy men

Yıl 2016, , 255 - 8, 15.06.2016

Tarik Yildirim , Eyup Avci Seda Elcim Yildirim Gokhan Aydin Ahmet Dolapoglu , Adil Ozan Gokuc

https://doi.org/10.17546/msd.94548

Öz

Background: Although the early re-polarization pattern known as a benign condition, it can result in idiopathic ventricular fibrillation and sudden cardiac death. In this study, we aimed to evaluate the prevalence of early repolarization pattern in young healthy men.

Methods and Patients: Four hundred fourteen young healthy man were enrolled in the study. PR intervals, QRS durations, QT intervals and corrected QT durations were measured from electrocardiographic records. Early re-polarization pattern was defined as if an elevation J-point was greater than 0,1 mV according to the isoelectrical point.

Results: The prevalence of early repolarization pattern was 23,2 % (n=96). Of these, we found early re-polarization pattern in inferior, lateral and inferolateral leads with 14,7%, 2,2% and 6,3% respectively. There was a significant relation between heart rate and elevation of J point. 

Conclusion: The prevalence of early repolarization pattern in young healthy men from Turkey was similar with the previously reported rates from different white populations.

Anahtar Kelimeler

Early repolarization, Healthy men; Cardiology

Prevalence of early repolarization pattern in young healthy men

Öz

Kaynakça

• Klatsky AL, Oehm R, Cooper RA, Udaltsova N, Armstrong MA. The early repolarization normal variant electrocardiogram: correlates and consequences. Am J Med 2003; 115: 171-7.
• Mehta M, Jain AC, Mehta A. Early repolarization. Clin Cardiol 1999; 22: 59-65.
• Haissaguerre M, Derval N, Sacher F, Jessel L, Deisenhofer I, de Roy L et al. Sudden cardiac arrest associated with early repolarization. N Engl J Med 2008;358:2016–23.
• Rosso R, Kogan E, Belhassen B, Rozovski U, Scheinman MM, Zeltser D et al. J-point elevation in survivors of primary ventricular fibrillation and matched control subjects: incidence and clinical significance. J Am Coll Cardiol 2008;52:1231–8.
• Abe A, Ikeda T, Tsukada T, Ishiquro A, Miwa Y, Miyakoshi M et al. Circadian variation of late potentials in idiopathic ventricular fibrillation associated with J waves: insights into alternative pathophysiology and risk stratification. Heart Rhythm 2010;7:675–82.
• Nam GB, Ko KH, Kim J, Park KM, Rhee KS, Choi KJ et al. Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs. Brugada syndrome. Eur Heart J 2010;31:330–9.
• Derval N, Simpson CS, Birnie DH, Healey JS, Chauan V,Champaqne J et al. Prevalence and characteristics of early repolarization in the CASPER registry: cardiac arrest survivors withpreserved ejection fraction registry. J Am Coll Cardiol 2011;58:722–8.
• Rosso R, Adler A, Halkin A, Viskin S. Risk of sudden death among young individuals with J waves and early repolarization: putting the evidence into perspective. Heart Rhythm 2011;8:923–9.
• Benito B, Guasch E, Rivard L, Nattel S. Clinical and mechanistic issues in early repolarization of normal variants and lethal arryhtmia syndromes. J Am Coll Cardiol 2010;56:1177-86.
• Sinner MF, Reinhard W, Muller M, Beckmann BM, Martens E, Perz S et al. Association of early repolarization pattern on ECG with risk of cardiac and all-cause mortality: a population-based prospective cohort study (MONICA/KORA). PLoS Med 2010;7:e1000314.
• Haruta D, Matsuo K, Tsuneto A, Ichimaru S, Hida A, Sera N et al. Incidence and prognostic value of early repolarization pattern in the 12–lead electrocardiogram. Circulation 2011;123:2931–7.
• Tikkanen JT, Anttonen O, Junttila MJ, Aro AL, Kerola T, Rissanen HA et al. Long-term outcome associated with early repolarization on electrocardiography. N Engl J Med 2009;361:2529-37.
• Tikkanen JT, Junttila MJ, Anttonen O, Aro AL, Luttinen S, Kerola T et al. Early repolarization: electrocardiographic phenotypes associated with favorable long-term outcome. Circulation 2011;123:2666-73.
• Noseworthy PA, Tikkanen JT, Porthan K, Oikarinen L, Pietila A, Harald K et al. The early repolarization pattern in the general population: clinical correlates and heritability. J Am Coll Cardiol 011;57:2284–9.
• Sarkozy A, Chierchia GB, Paparella G, Boussy T, De Asmundis C, Roos M et al. Inferior and lateral electrocardiographic repolarization abnormalities in Brugada syndrome. Circ Arrhythm Electrophysiol 2009;2:154–61.
• Watanabe H, Makiyama T, Koyama T, Kannankeril PJ, Seto S, Okamura K et al. High prevalence of early repolarization in short QT syndrome. Heart Rhythm 2010;7:647–52.
• Osborn JJ. Experimental hypothermia; respiratory and blood pH changes in relation to cardiac function. Am J Physiol 1953;175:389–98.