A rare case of necrotizing sialometaplasia of palate treated with intralesional steroid
Yıl 2018,
, 24 - 27, 28.06.2018
H.bengu Cobanoglu
,
Selcuk Arslan
,
İsmail Saygın
Öz
Necrotizing sialometaplasia is a rare, benign, inflammatory disease of minor salivary glands and is similar in appearance to malignant lesions. A rare case of necrotizing sialometaplasia in palate treated with intra-lesional steroids is presented. A 65-year-old male patient had an ulcerated lesion of approximately 1x2 cm in size near the midline in palate that had not healed for 2 weeks . The biopsy findings were in agreement with the diagnosis of necrotizing sialometaplasia. The patient was treated with a single dose of intralesional 40 mg triamcinolone acetonide. At the end of the second week, the lesion was completely healed. Necrotizing sialometaplasia is an inflammatory disease that can mimic malignancies. Spontaneous healing is possible, and occurs from 4 to 10 weeks. Intra-lesional steroid administration can be considered as a treatment option that accelerates healing in this rare disease.
Kaynakça
- 1. Mesa ML, Gertler RS, Schneider LC. Necrotizing sialometaplasia: Frequency of histologic misdiagnosis. Oral Surg Oral Med Oral Pathol. 1984;57:71–3.
- 2. Abrams AM, Melrose RJ, Howell FV. Necrotizing sialometaplasia. A disease simulating malignancy. Cancer. 1973;32:130–5.
- 3. Brannon RB, Fowler CB, Hartman KS. Necrotizing sialometaplasia-A clinicopathologic study of sixty-nine cases and review of the literature. Oral Surg Oral Med Oral Pathol. 1991;72:317–25.
- 4. Krishna S, BK R. Necrotizing sialometaplasia of palate: A case report. Imaging Sci Dent. 2011;41(1):35–38.
- 5. Fowler CB, Brannon RB. Subacute necrotizing sialadenitis: Report of 7 cases and a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.2000;89:600–9.
- 6. Daudia A, Murty GE. First case of full-thickness palatal necrotizing sialometaplasia. J Laryngol Otol. 2002;116:219–20.
- 7. Nah KS, Cho BH, Jung YH. Necrotizing sialometaplasia: Report of 2 cases. Korean J Oral Maxillofac Radiol. 2006;36:207–9.
- 8. Marx RE, Stern D. 1st ed. New Delhi: Quintessence Publishing Co, Inc; 2003. Oral and maxillofacial pathology a rationale for diagnosis and treatment; pp. 509–10.
Damakta intralezyonel steroid ile tedavi edilen nadir bir nekrotizan sialometaplazi olgusu
Yıl 2018,
, 24 - 27, 28.06.2018
H.bengu Cobanoglu
,
Selcuk Arslan
,
İsmail Saygın
Öz
Nekrotizan sialometaplazi, minör tükrük bezlerinden
kaynaklanan oldukça nadir, benign, inflamatuar bir hastalık olup görünüm olarak
malign lezyonlara benzemektedir. İntralezyonel steroid ile tedavi edilen damak
yerleşimli nadir bir nekrotizan sialometaplazi olgusu sunulmaktadır. Altmış beş
yaşında erkek hastada 2 haftadır damağında iyileşmeyen orta hatta yakın
yaklaşık 1x 2 cm boyutlu ülsere lezyon görüldü. Lezyondan alınan biyopsi sonucu
nekrotizan sialometaplazi ile uyumlu olarak kaydedildi. Hastaya tek sefer intralezyonel
40 mg triamsinolon asetonid tedavisi uygulandı. Tedavi sonrası ikinci haftada lezyonun
tamamen iyileştiği izlendi. Nekrotizan sialometaplazi inflamatuar bir hastalık
olup maligniteleri taklit edebilmektedir. Kendiliğinden iyileşme mümkün olup 4
ila 10 hafta arasında değişmektedir. İntralezyonel steroid uygulaması
iyileşmeyi hızlandıran bir tedavi seçeneği olarak bu nadir hastalıkta göz
önünde bulundurulabilir.
Kaynakça
- 1. Mesa ML, Gertler RS, Schneider LC. Necrotizing sialometaplasia: Frequency of histologic misdiagnosis. Oral Surg Oral Med Oral Pathol. 1984;57:71–3.
- 2. Abrams AM, Melrose RJ, Howell FV. Necrotizing sialometaplasia. A disease simulating malignancy. Cancer. 1973;32:130–5.
- 3. Brannon RB, Fowler CB, Hartman KS. Necrotizing sialometaplasia-A clinicopathologic study of sixty-nine cases and review of the literature. Oral Surg Oral Med Oral Pathol. 1991;72:317–25.
- 4. Krishna S, BK R. Necrotizing sialometaplasia of palate: A case report. Imaging Sci Dent. 2011;41(1):35–38.
- 5. Fowler CB, Brannon RB. Subacute necrotizing sialadenitis: Report of 7 cases and a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod.2000;89:600–9.
- 6. Daudia A, Murty GE. First case of full-thickness palatal necrotizing sialometaplasia. J Laryngol Otol. 2002;116:219–20.
- 7. Nah KS, Cho BH, Jung YH. Necrotizing sialometaplasia: Report of 2 cases. Korean J Oral Maxillofac Radiol. 2006;36:207–9.
- 8. Marx RE, Stern D. 1st ed. New Delhi: Quintessence Publishing Co, Inc; 2003. Oral and maxillofacial pathology a rationale for diagnosis and treatment; pp. 509–10.