Primary Squamous Cell Carcinoma of the Breast. A Case Report with Review of the Literature

Yıl 2023, Cilt: 10 Sayı: 1, 75 - 77, 10.04.2023

Ahmet Cem Esmer , Ahmet Dağ

https://doi.org/10.47572/muskutd.1073966

Öz

Primary squamous-cell carcinoma of the breast is a rare entity classified under the metaplastic carcinomas of the breast. The prognosis is poor, and there is no consensus for clinical treatment that is multi-modal treatment options of surgery, chemotherapy, and radiation therapy. In our case, all the locations that can develop squamous-cell carcinoma were scanned, and no tumors were found in these foci. Histopathological examination of our case matched the verrucous carcinoma variant of primary squamous-cell carcinoma of the breast. We presented 30-year-old female primary squamous-cell carcinoma of the left breast due to a rare clinical entity, and the recent literature is reviewed and presented.

Anahtar Kelimeler

Breast Cancer, Metaplastic Carcinomas Of Breast, Squamous Cell Carcinoma

Memenin Primer Skuamöz Hücreli Karsinomu. Olgu Sunumu Eşliğinde Literatürün Gözden Geçirilmesi

Öz

Memenin primer skuamöz hücreli karsinomu nadir görülüp memenin metaplastik karsinomları içerisinde yer alır. Prognoz kötü olmasına bağlı olarak cerrahi, radyoterapi ve kemoterapiyi içeren çoklu tedavi yaklaşımları mevcut olup tedavi protokolü üzerine anlaşılmış bir konsensus mevcut değildir. Olgumuzda skuamöz hücreli karsinomun gelişebileceği organlar tarandı ve bu odaklarda tümör saptanmadı. Sunulan olguda hispatolojik inceleme ile memenin primer skuamöz hücreli karsinomunun verrüköz varyantı ile uyumlu olarak geldi. Klinik olarak nadir gözlenmesi nedeniyle 30 yaşında kadın hastada sol memede primer skuamöz hücreli karsinom tespit edilen hasta literatür bilgileri eşliğinde tartışıldı.

Anahtar Kelimeler

Meme Kanseri, Memenin Metaplastik Karsinomları, Primer Skuamöz Hücreli Karsinomu

Kaynakça

• 1. Gupta G, Malani AK, Weigand RT, et al. Pure primary squamous cell carcinoma of the breast: a rare presentation and clinicopathologic comparison with usual ductal carcinoma of the breast. Pathol Res Pract. 2006;6:465–9.
• 2. Badge SA, Gangane NM, Shivkumar VB, et al. Primary squamous cell carcinoma of the breast. Int J Appl Basic Med Res. 2014;4(1):53-5.
• 3. Mayadağlı A, Ekici K, Kökten Ş, et al. Primary squamous cell carcinoma of the breast: Case report and review of the literature. Okmeydanı Tıp Derg. 2012;28(2):112-4.
• 4. Siegelmann-Danieli N, Murphy TJ, Meschter SC, et al. Primary pure squamous cell carcinoma of the breast. Clin Breast Cancer. 2005;6(3):270-2.
• 5. Anne N, Sulger E, Pallapothu R. Primary squamous cell carcinoma of the breast: a case report and review of the literature. J Surg Case Rep. 2019;6:1–4.
• 6. Gül AE, Yıldız C, Dalkılıç G, et al. Memenin primer skuamöz hücreli karsinomu: olgu sunumu. Kartal Eğit Araşt Hast Tıp Derg. 2006;XVII(2):89-92.
• 7. Guo T, Chen Z, Xu J, et al. Change of pathological type to metaplastic squamous cell carcinoma of the breast during disease recurrence: case report and literature review. Front Oncol. 2020;10:32.
• 8. Badge SA, Gangane NM, Shivkumar VB, et al. Primary squamous cell carcinoma of the breast. Int J Appl Basic Med Res. 2014;4:53–5.
• 9. Aparicio I, Martinez A, Hernandez G, et al. Squamous cell carcinoma of the breast. Eur J Obstet Gynecol. 2008;137:222.
• 10. Han Y, Wang J, Wang Z, et al. Clinicopathological characteristics and prognosis of squamous cell carcinoma of the breast: a population-based analysis. Cancer Control. 2021;28:10732748211044355.
• 11. Brogi E. Metaplastic carcinoma including low-grade adenosquamous carcinoma. Chapter 19. In: Brogi E, Syed AH, Koerner FC, Rosen PR. (eds.) Rosen’s Diagnosis of Breast Pathology by Needle Core Biopsy4th ed. Philadelphia: Lippincott Williams and Wilkins; 2017.p.469-5007.
• 12. Carbone S, Alvarez RL, Lamacchia A, et al. Primary squamous cell carcinoma of the breast: a rare case report. Rep Pract Oncol Radiother. 2012;17:363–6.
• 13. Gürsel B, Bayrak IK, Gokce SC, et al. Primary squamous cell carcinoma of the breast: A case report and review of the literature. Turk J Cancer. 2007;37:114–6.
• 14. Menes T, Schachter J, Morgenstern S, et al. Primary squamous cell carcinoma (SqCC) of the breast. Am J Clin Oncol. 2003;26:571-3.