KONYA İLİ KIRSALINDA KIRIM KONGO KANAMALI ATEŞİ VİRUSUNUN ARAŞTIRILMASI

Öz

ÖZET Amaç: Kırım Kongo Kanamalı Ateşi (KKKA), keneler yoluyla insanlara bulaşabilen önemli viral enfeksiyonlardan birisidir. Hayvanlar, herhangi bir hastalık belirtisi göstermeden KKKA virusunu (KKKAV) alabilirler. Hayvanlarda KKKAV'nin saptanması, sahada KKKAV'nin sirkülasyonunun bir işareti olarak kullanılabilir. Bu nedenle, bu çalışmanın amacı koyun ve keçilerde KKKAV prevalansını belirlemekti. Gereç ve Yöntem: Bu çalışmada, Konya İl’indeki epidemiyolojik olarak bağımsız sürülerden (n = 29),161 koyun ve 106 keçiden alınan kan ve serum (n = 267) örnekleri kullanılarak KKKA prevalansı araştırıldı Bulgular: Küçükbaş hayvanlarda seropozitifliğin %21,3 (%95 CI 16,4 - 26,2) olduğu belirlendi. KKKAV spesifik antikorlar 30 koyunda (%18,6, %95 CI: 12,6 - 24,7) saptanırken, 106 keçinin 27’si (%25,5, %95 CI: 17,2 - 33,8) pozitif bulundu. KKKAV seropozitifliği türler (p = 0,222) ve cinsiyetler (p = 0,455) arasında istatistiksel olarak farklı değildi. KKKAV RNA’sı tespit edilmedi. KKKAV seropozitifliği 2 yaşından büyük hayvanlarda daha yüksekti (p = 0,009). Sonuçlar: Mevcut çalışmanın sonuçları, KKKAV’nin çalışma alanındaki küçükbaş hayvanlarda sirküle olduğunu ve insanların KKKAV enfeksiyonuna yakalanma riski altında olduğunu göstermektedir. Türkiye'de KKKAV odaklarını belirlemek için gelecekteki epidemiyolojik çalışmalara ihtiyaç vardır.

Anahtar Kelimeler

• Kırım Kongo kanamalı ateşi virusu
• prevalans
• küçük ruminant
• risk faktörleri

A SURVEY of CRIMEAN-CONGO HAEMORRHAGIC FEVER VIRUS in RURAL AREAS of KONYA PROVINCE

Öz

ABSTRACT Aim: Crimean-Congo haemorrhagic fever (CCHF) is one of the major viral infections that may be spread by ticks to humans. Animals can get the CCHV virus (CCHFV) without showing any symptoms of disease. Detection of CCHFV in animals can be used as a sign for the circulation of virus in the field. Therefore, the purpose of this study was to determine the prevalence of CCHFV in sheep and goats. Material and Methods: In this study, prevalence of CCHF was investigated using blood and sera (n = 267) samples from 161 sheep and 106 goats from epidemiologically independent flocks (n = 29) in the Konya Province. Results: The seropositivity in small ruminants was 21.3% (95% CI 16.4 - 26.2). CCHFV specific antibodies were detected in 30 sheep (18.6%, 95% CI: 12.6 - 24.7) whereas 27 out of the 106 goats (25.5%, 95% CI: 17.2 - 33.8) was found positive. CCHFV seropositivity was not statistically different between species (p = 0.222) and sexes (p = 0.455). CCHFV RNA was not detected. Seropositivity of CCHFV was higher in animals older than 2 years old (p = 0.009). Conclusion: The current study’s results suggest that CCHFV circulates in small ruminants in study area and people are at risk of getting CCHFV infection. Future epidemiological studies are required to determine foci of CCHFV in Türkiye.

Anahtar Kelimeler

• Crimean-Congo haemorrhagic fever virus
• prevalence
• small ruminants
• risk factors

Kaynakça

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