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Seryum (133,135Ce) erbiyum (165Er) ve platin (187Pt) radyoizotoplarının üretim tesir kesiti değerlerinin incelenmesi

Yıl 2025, Sayı: 4, 171 - 179
https://doi.org/10.70846/nigdetip.1787894

Öz

Bu çalışmada nükleer tıpta teşhis ve tedavide kullanılan Seryum (133,135Ce) Erbiyum (165Er) ve platin (187Pt) radyoizotoplarının üretim tesir kesitleri nükleer benzeşim kodları ile hesaplanarak, literatürden alından deneysel verilerle karşılaştırılmıştır. Teorik reaksiyon üretim tesir kesiti hesaplamaları literatürde yaygın olarak EMPIRE, HIVAP, PACE4 ve TALYS kodları kullanılarak gerçekleştirilmektedir. Bu çalışma kapsamında bazı radyoizotopların reaksiyon tesir kesiti değerleri ilk kez EMPIRE-3.2, HIVAP, PACE4, ve TALYS 1.4 hesaplama kodlarıyla hesaplanmış ve literatürdeki deneysel reaksiyon tesir kesiti değerleri ile karşılaştırılmıştır. Çalışma kapsamında kullanılan deneysel veriler; Deneysel Nükleer Reaksiyon Veri Kütüphanesi (EXFOR/CSISRS) den alınmıştır.

Kaynakça

  • Şekerci M, Özdoğan H, Kaplan A. 75-77Br radyoizotoplarının üretim tesir kesiti hesaplamalarında bazı seviye yoğunluğu modellerinin etkilerinin incelenmesi. Erzincan Univ J Sci Technol. 2020;13(2):719-729. doi:10.18185/erzifbed.715299
  • Tarasov OB, Bazin D. Development of the program LISE: application to fusion–evaporation. Nucl Instrum Methods Phys Res B. 2003;204:174-178. doi:10.1016/S0168-583X(02)01917-1
  • Herman M, Trkov A. ENDF-6 Formats Manual. National Nuclear Data Center, Brookhaven National Laboratory; 2022. Available from: https://www-nds.iaea.org/public/endf/endf-manual.pdf
  • Reisdorf W. Analysis of fissionability data at high excitation energies. Z Phys A. 1981;300:227-238.
  • Koning A, Hilaire S, Goriely S. TALYS User Manual. TENDL-2019 nuclear data library; 2019. Available from: https://tendl.web.psi.ch/tendl_2019/talys.html
  • Koning A, Hilaire S, Goriely S. Talys tutorial simulation of nuclear reaction. 2021. Available from: https://nds.iaea.org/TALYS
  • Kaplan A, Şekerci M, Özdoğan H, Demir B. A study on the calculations of cross-sections for 66,67Ga and 75Se radionuclides production reactions via 3He particles. Eskisehir Tech Univ J Sci Technol A Appl Sci Eng. 2020;21(4):554-561. doi:10.18038/estubtda.761276
  • Üncü YA, Özdoğan H, Şekerci M, Kaplan A. Investigation of the production routes of palladium-103 and iodine-125 radioisotopes. Radiat Phys Chem. 2023;204:110658. doi:10.1016/j.radphyschem.2022.110658
  • Yigit M, Kara A. Simulation study of the proton-induced reaction cross section for the production of F-18 and Ga-66-68 radioisotopes. J Radioanal Nucl Chem. 2017;314(3):2383-2392.
  • Tárkányi F, Ditrói F, Takács S, Hermanne A, Ignatyuk AV, Spahn I, et al. Investigation of activation cross-section of deuteron induced reaction on ruthenium up to 50 MeV. Appl Radiat Isot. 2021;168:109401. doi:10.1016/j.apradiso.2020.109401
  • Hasan GH, Nury EMT, Groppi F. Evaluation of cross-section data for radionuclides used in positron emission tomography by effects of level density models using EMPIRE 3.2.2 Code. Nucl Phys At Energy. 2022;22(3):237-242. doi:10.15407/jnpae2021.03.237
  • Özdoğan H, Sarpun IH, Şekerci M, Kaplan A. Production cross-section calculations of In-111 via proton and alpha-induced nuclear reactions. Mod Phys Lett A. 2021;36(8):2150051. doi:10.1142/S0217732321500516
  • Kara A, Korkut T, Yigit M, Tel E. Modelling on production cross section of In-111 radioisotopes used in nuclear medicine. Kerntechnik. 2015;80(3):270-274. doi:10.3139/124.110527
  • Choudhury D, Lahiri S. Production cross-section of Au-190-193 radioisotopes produced from B11+W-nat reactions up to 63 MeV projectile energy. Eur Phys J A. 2019;55(9). doi:10.1140/epja/i2019-12858-3
  • Singh N. Radioisotopes applications in bio-medical science. In: IntechOpen; 2011. Available from: https://www.intechopen.com/books/1481
  • Halasz Z, Gyürky Gy, Farkas J, Fülöp Zs, Szücs T, Somorjai E. Investigation of α-induced reactions on 130Ba and 132Ba and their importance for the synthesis of heavy p nuclei. Phys Rev C. 2012;85:025804. doi:10.1103/PhysRevC.85.025804
  • Tárkányi F, Hermanne A, Ditrói F, Takács S. Activation cross section data of proton induced nuclear reactions on lanthanum in the 34–65 MeV energy range and application for production of medical radionuclides. J Radioanal Nucl Chem. 2017;312:691-704. doi:10.1007/s10967-017-5253-7
  • Singh D, Sneha BL, Giri PK, Mahato A, Tripathi R, Kumar H, et al. Measurement of excitation functions of evaporation residues in the 16O + 124Sn reaction and investigation of the dependence of incomplete fusion dynamics on entrance channel parameters. Phys Rev C. 2018;97:064610. doi:10.1103/PhysRevC.97.064610
  • Tárkányi F, Hermanne A, Ditrói F, Takács S, Király B, Kovalev SF, Ignatyuk AV. Experimental study of the 165Ho(d,2n) and 165Ho(d,p) nuclear reactions up to 20 MeV for production of the therapeutic radioisotopes 165Er and 166gHo. Nucl Instrum Methods Phys Res B. 2008;266:3529-3534. doi:10.1016/j.nimb.2008.05.123
  • Prajapat R, Kumar D, Kumar K, Chauhan A. Production of 187Pt radionuclide from 11B-induced reaction on natTa. Proc DAE Symp Nucl Phys. 2018;63.
  • Hermanne A, Adam-Rebeles R, Tarkanyi F, Takacs S, Csikai J, et al. Deutereon induced reactions on Ho and La: experimental excitation functions and comparison with code result. Nuclear Instruents and Methods in Physics Research B. 2013;311,102-101
  • Isotopes of cerium. Wikipedia. Available from: https://en.wikipedia.org/wiki/Isotopes_of_cerium
  • Isotopes of erbium. Wikipedia. Available from: https://en.wikipedia.org/wiki/Isotopes_of_erbium
  • Isotopes of platinum. Wikipedia. Available from: https://en.wikipedia.org/wiki/Isotopes_of_platinum
  • GetData Graph Digitizer. Available from: https://getdata-graph-digitizer.software.informer.com/

Investigation of Production Cross Section Values ​​of Cerium (133,135Ce), Erbium (165Er) and Platinum (187Pt) Radioisotopes

Yıl 2025, Sayı: 4, 171 - 179
https://doi.org/10.70846/nigdetip.1787894

Öz

The production cross sections of the radioisotopes Cerium (133, 135Ce) were examined in this study., Erbium (165Er) and platinum (187Pt) used in diagnosis and treatment in nuclear medicine were calculated with nuclear affinity codes and compared to experimental information found in the literature. Theoretical reaction effect cross-section calculations were performed using PACE4, EMPIRE, HIVAP and TALYS codes are widely used in the literature. With the aid of the calculation codes EMPIRE-3.2, HIVAP, PACE4, and TALYS 1.4, the reaction cross section values of a few radioisops were calculated for the first time in this study and compared to the experimental reaction cross section values published in the literature. The Experimental Nuclear Reaction Data Library (EXFOR/CSISRS) provided the experimental data used in the investigation.

Kaynakça

  • Şekerci M, Özdoğan H, Kaplan A. 75-77Br radyoizotoplarının üretim tesir kesiti hesaplamalarında bazı seviye yoğunluğu modellerinin etkilerinin incelenmesi. Erzincan Univ J Sci Technol. 2020;13(2):719-729. doi:10.18185/erzifbed.715299
  • Tarasov OB, Bazin D. Development of the program LISE: application to fusion–evaporation. Nucl Instrum Methods Phys Res B. 2003;204:174-178. doi:10.1016/S0168-583X(02)01917-1
  • Herman M, Trkov A. ENDF-6 Formats Manual. National Nuclear Data Center, Brookhaven National Laboratory; 2022. Available from: https://www-nds.iaea.org/public/endf/endf-manual.pdf
  • Reisdorf W. Analysis of fissionability data at high excitation energies. Z Phys A. 1981;300:227-238.
  • Koning A, Hilaire S, Goriely S. TALYS User Manual. TENDL-2019 nuclear data library; 2019. Available from: https://tendl.web.psi.ch/tendl_2019/talys.html
  • Koning A, Hilaire S, Goriely S. Talys tutorial simulation of nuclear reaction. 2021. Available from: https://nds.iaea.org/TALYS
  • Kaplan A, Şekerci M, Özdoğan H, Demir B. A study on the calculations of cross-sections for 66,67Ga and 75Se radionuclides production reactions via 3He particles. Eskisehir Tech Univ J Sci Technol A Appl Sci Eng. 2020;21(4):554-561. doi:10.18038/estubtda.761276
  • Üncü YA, Özdoğan H, Şekerci M, Kaplan A. Investigation of the production routes of palladium-103 and iodine-125 radioisotopes. Radiat Phys Chem. 2023;204:110658. doi:10.1016/j.radphyschem.2022.110658
  • Yigit M, Kara A. Simulation study of the proton-induced reaction cross section for the production of F-18 and Ga-66-68 radioisotopes. J Radioanal Nucl Chem. 2017;314(3):2383-2392.
  • Tárkányi F, Ditrói F, Takács S, Hermanne A, Ignatyuk AV, Spahn I, et al. Investigation of activation cross-section of deuteron induced reaction on ruthenium up to 50 MeV. Appl Radiat Isot. 2021;168:109401. doi:10.1016/j.apradiso.2020.109401
  • Hasan GH, Nury EMT, Groppi F. Evaluation of cross-section data for radionuclides used in positron emission tomography by effects of level density models using EMPIRE 3.2.2 Code. Nucl Phys At Energy. 2022;22(3):237-242. doi:10.15407/jnpae2021.03.237
  • Özdoğan H, Sarpun IH, Şekerci M, Kaplan A. Production cross-section calculations of In-111 via proton and alpha-induced nuclear reactions. Mod Phys Lett A. 2021;36(8):2150051. doi:10.1142/S0217732321500516
  • Kara A, Korkut T, Yigit M, Tel E. Modelling on production cross section of In-111 radioisotopes used in nuclear medicine. Kerntechnik. 2015;80(3):270-274. doi:10.3139/124.110527
  • Choudhury D, Lahiri S. Production cross-section of Au-190-193 radioisotopes produced from B11+W-nat reactions up to 63 MeV projectile energy. Eur Phys J A. 2019;55(9). doi:10.1140/epja/i2019-12858-3
  • Singh N. Radioisotopes applications in bio-medical science. In: IntechOpen; 2011. Available from: https://www.intechopen.com/books/1481
  • Halasz Z, Gyürky Gy, Farkas J, Fülöp Zs, Szücs T, Somorjai E. Investigation of α-induced reactions on 130Ba and 132Ba and their importance for the synthesis of heavy p nuclei. Phys Rev C. 2012;85:025804. doi:10.1103/PhysRevC.85.025804
  • Tárkányi F, Hermanne A, Ditrói F, Takács S. Activation cross section data of proton induced nuclear reactions on lanthanum in the 34–65 MeV energy range and application for production of medical radionuclides. J Radioanal Nucl Chem. 2017;312:691-704. doi:10.1007/s10967-017-5253-7
  • Singh D, Sneha BL, Giri PK, Mahato A, Tripathi R, Kumar H, et al. Measurement of excitation functions of evaporation residues in the 16O + 124Sn reaction and investigation of the dependence of incomplete fusion dynamics on entrance channel parameters. Phys Rev C. 2018;97:064610. doi:10.1103/PhysRevC.97.064610
  • Tárkányi F, Hermanne A, Ditrói F, Takács S, Király B, Kovalev SF, Ignatyuk AV. Experimental study of the 165Ho(d,2n) and 165Ho(d,p) nuclear reactions up to 20 MeV for production of the therapeutic radioisotopes 165Er and 166gHo. Nucl Instrum Methods Phys Res B. 2008;266:3529-3534. doi:10.1016/j.nimb.2008.05.123
  • Prajapat R, Kumar D, Kumar K, Chauhan A. Production of 187Pt radionuclide from 11B-induced reaction on natTa. Proc DAE Symp Nucl Phys. 2018;63.
  • Hermanne A, Adam-Rebeles R, Tarkanyi F, Takacs S, Csikai J, et al. Deutereon induced reactions on Ho and La: experimental excitation functions and comparison with code result. Nuclear Instruents and Methods in Physics Research B. 2013;311,102-101
  • Isotopes of cerium. Wikipedia. Available from: https://en.wikipedia.org/wiki/Isotopes_of_cerium
  • Isotopes of erbium. Wikipedia. Available from: https://en.wikipedia.org/wiki/Isotopes_of_erbium
  • Isotopes of platinum. Wikipedia. Available from: https://en.wikipedia.org/wiki/Isotopes_of_platinum
  • GetData Graph Digitizer. Available from: https://getdata-graph-digitizer.software.informer.com/
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Nükleer Tıp
Bölüm Araştırma Makalesi
Yazarlar

Birgül Eren 0000-0003-0403-5000

Sefa Erturk 0000-0003-4051-9096

Erken Görünüm Tarihi 24 Kasım 2025
Yayımlanma Tarihi 25 Kasım 2025
Gönderilme Tarihi 20 Eylül 2025
Kabul Tarihi 21 Ekim 2025
Yayımlandığı Sayı Yıl 2025 Sayı: 4

Kaynak Göster

Vancouver Eren B, Erturk S. Seryum (133,135Ce) erbiyum (165Er) ve platin (187Pt) radyoizotoplarının üretim tesir kesiti değerlerinin incelenmesi. Niğde Tıp Dergisi. 2025(4):171-9.