Formulation, stability and analytical method validation of peppermint oil solution

Yıl 2019, Cilt: 6 Sayı: 2, 25 - 31, 28.06.2019

İlker Demirbolat

Öz

Tension type headache is the most common type of
headaches causing mild, moderate and intense pain in the forehead and neck. There
are prescription medicines -usually nonsteroidal anti-inflammatory drugs- and
herbal remedies to alleviate the pain. As peppermint (Mentha piperita L.) is one of those most used medicinal plants in
the world, essential oil has also a wide range of medical applications like
tension type headache. The legislation to conventional medicines applies to
herbal medicinal products too, which makes registered herbal medicinal products
reliable in production and quality. A CTD application dossier which contains production
and quality control data in module three should be provided while registering a
product in European Union. In this study a peppermint oil solution is developed
and analytical method is validated to control the stability of solution
indicated for tension type headaches.

Anahtar Kelimeler

Peppermint, Mentha piperita L., Analytical Method Validation, Formulation

Kaynakça

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