Chemical composition of the essential oil of Diospyros wallichii King & Gamble (Ebenaceae)

Yıl 2020, Cilt: 7 Sayı: 3, 12 - 17, 07.09.2020

Wan Mohd Nuzul Hakimi Wan Salleh Shamsul Khamis

Öz

The chemical composition of the essential oil from the leaves of Diospyros wallichii (Ebenaceae) growing in Malaysia was investigated
for the first time. The essential oil was obtained by hydrodistillation and fully characterized by gas chromatography (GC-FID) and gas
chromatography-mass spectrometry (GC-MS). A total of 34 components (95.8%) were successfully identified in the essential oil which
were characterized by high proportions of β-eudesmol (28.5%), caryophyllene oxide (9.5%), β-caryophyllene (7.2%), α-eudesmol
(6.5%) and germacrene D (6.2%).

Anahtar Kelimeler

Ebenacea, Diospyros wallichii, essential oil, hydrodistillation, β-eudesmol, GC-MS

Kaynakça

• Adams, R. P. (2007). Identification of essential oil components by gas chromatography/mass spectroscopy. Carol Stream (IL): Allured.
• Chiou, L. C., Ling, J. Y., & Chang, C. C. (1995). β-Eudesmol as an antidote for intoxication from organophosphorus anticholinesterase agents. European Journal of Pharmacology, 292, 151-156.
• Chiou, L. C., Ling, J. Y., & Chang, C. C. (1997). Chinese herb constituent β-eudesmol alleviated the electroshock seizures in mice and electrographic seizures in rat hippocampal slices. Neuroscience Letters, 231, 171-174.
• Kimura, Y., & Sumiyoshi, M. (2012). Effects of an Atractylodes lancea rhizome extract and a volatile component β-eudesmol on gastrointestinal motility in mice. Journal of Ethnopharmacolpgy, 141, 530-536.
• Lim, D. Y., & Kee, Y. W. (2005). Influence of β-eudesmol on blood pressure. Natural Product Sciences, 11, 33-40.
• Mallavadhani, U. V., Panda, A. K., & Rao, Y. R. (1998). Pharmacology and Chemotaxonomy of Diospyros. Phytochemistry, 49, 901-951.
• Nematollahi, A., Aminimoghadamfarou, N., Bradshaw, T. D., & Wiart, C. (2012). In vitro cytotoxic activity of two malaysian rainforest plants on colon carcinoma cell-line. Asian Journal of Pharmaceutical and Health Sciences, 2(1), 293-295.
• Obara, Y., Aoki, T., Kusano, M., & Ohizumi, Y. (2002). β-Eudesmol induces neurite outgrowth in rat pheochromocytoma cells accompanied by an activation of mitogen-activated protein kinase. Journal of Pharmacology and Experimental Therapeutics, 301, 803-811.
• Pino, J., Glory, L. C., & Fuentes, V. (2008). Volatile components of Mabolo (Diospyros blancoi A.DC.) Grown in Cuba. Journal of Essential Oil Research, 20(6), 506-508.
• Plengsuriyakarn, T., Karbwang, J., & Na-Bangchang, K. (2015). Anticancer activity using positron emission tomography-computed tomography and pharmacokinetics of β-eudesmol in human cholangiocarcinoma xenografted nude mouse model. Clinical and Experimental Pharmacology and Physiology, 42, 293-304.
• Rauf, A., Uddin, G., Patel, S., Khan, A., Halim, S. A., Bawazeer, S., Ahmad, K., Muhammad, N., & Mubarak, M. S. (2017). Diospyros, an under-utilized, multi-purpose plant genus: A review. Biomedicine & Pharmacotherapy, 91, 714-730.
• Salae, A. W., Karalai, C., Ponglimanont, C., Kanjana-Opas, A., & Yuenyongsawad, S. (2010). Naphthalene derivatives from Diospyros wallichii. Canadian Journal of Chemistry, 88, 922-927.
• Salleh, W. M. N. H. W., Ahmad, F., & Khong, H. Y. (2014). Chemical compositions and antimicrobial activity of the essential oils of Piper abbreviatum, P. erecticaule and P. lanatum (Piperaceae). Natural Product Communications, 9(12), 1795-1798.
• Salleh, W. M. N. H. W., Ahmad, F., & Khong, H. Y. (2015a). Antioxidant and anticholinesterase activities of essential oils of Cinnamomum griffithii and C. macrocarpum. Natural Product Communications, 10(8), 1465-1468.
• Salleh, W. M. N. H. W., Kamil, F., Ahmad, F., & Sirat, H. M. (2015b). Antioxidant and anti-inflammatory activities of essential oil and extracts of Piper miniatum. Natural Product Communications, 10(11), 2005-2008.
• Salleh, W. M. N. H. W., Ahmad, F., Khong, H. Y., & Zulkifli, R. M. (2016a). Comparative study of the essential oils of three Beilschmiedia species and their biological activities. International Journal of Food Science and Technology, 51, 240-249.
• Salleh, W. M. N. H. W., Ahmad, F. (2016b). Antioxidant and anti-inflammatory activities of essential oils of Actinodaphne macrophylla and A. pruinosa (Lauraceae). Natural Product Communications, 11(6): 853-855.
• Smith, R. M., & Belardo, L. O. (1992). Volatile compounds from the fruit peelings of Diospyros discolor Willd. Journal of Essential Oil Research, 4, 287-289.
• Smitinand, T. (2001). Thai Plant Names. The Forest Herbarium, Royal Forest Dept., Bangkok.
• Su, Y. C., Hsu, K. P., Wang, E. I. C., & Ho, C. L. (2015). Composition, in vitro cytotoxic, and antimicrobial activities of the flower essential oil of Diospyros discolor from Taiwan. Natural Product Communications, 10, 1311-1314.
• The Plant List (2012). Version 1. Retrieved from http://www.theplantlist.org/
• Tsuneki, H., Ma, E. L., Kobayashi, S., Sekizaki, N., Maekawa, K., Sasaoka, T., Wang, M. W., & Kimura, I. (2005). Antiangiogenic activity of β-eudesmol in vitro and in vivo. European Journal of Pharmacology, 512, 105-115.
• Utsunomiya, N., Subhadrabandhu, S., Yonemori, K., Oshida, M., Kanzaki, S., Nakatsubo, F., & Sugiura, A. (1998). Diospyros species in Thailand: their distribution, fruit morphologhy and uses. Economic Botany, 52, 343-351.
• Viswanathan, M. B., Maridass, M., Thangadurai, & D., Ramesh, N. (2002). Chemical constituents of the fruit essential oil of Diospyros malabarica (Desr.) Kostel (Ebenaceae). Acta Pharmaceutica, 52, 207-211.
• Yang, Y. P., & Liu, H. Y. (1999). Manual of Taiwan vascular plants. Council of Agriculture, Taipei, Taiwan.