THE INCIDENCE AND SIGNIFICANCE OF INCIDENTAL PROSTATE CARCINOMA IN TRANSURETHRAL RESECTION (TUR-P) MATERIALS BETWEEN 2014 AND 2016 AT OUR CENTER

Yıl 2018, Cilt: 13 Sayı: 2, 19 - 22, 21.04.2018

Gülname Fındık Güvendi Tuğba Toyran Murat Bağcıoglu Özlem Kılıç Yasemen Adalı

Öz

Incidence and significance of incidental prostate carcinoma in transurethral resection (TUR-P) materials between 2014 and 2016 at our center. Like all organs, prostate has benign and malign diseases. Among benign diseases, benign prostatic hyperplasia (BPH) and among malignancies adenocarcinoma are the most common ones. One of the methods that is used to treat BPH is transurethral resection (TUR-P). In our study, we investigated incidental tumor rates observed in patients that have TUR-P due to BPH. We included 120 patients who underwent TUR-P and whose operation materials were examined in pathology department between 2014-2016 in our center. Benign diseases were noted in 117 (97.5%) of 120 patients, whereas malignant tumors were detected in 3 (2.5%) cases. In TUR-P operations performed to relieve symptoms in BPH, adenocarcinoma is reported in the literature at rates ranging from 4% to 15%. We suggest that patients with symptoms of prostatism should be carefully investigated, detailed histopathologic evaluation should be done in terms of incidental tumors and clinical pathology communication should be at maximum level.

Anahtar Kelimeler

Prostate, Carcinoma, Adenocarcinoma, Incidental, TUR-P

THE INCIDENCE AND SIGNIFICANCE OF INCIDENTAL PROSTATE CARCINOMA IN TRANSURETHRAL RESECTION (TUR-P) MATERIALS BETWEEN 2014 AND 2016 AT OUR CENTER

Öz

Incidence and significance of incidental prostate carcinoma in
transurethral resection (TUR-P) materials between 2014 and 2016 at our center. Like
all organs, prostate has benign and malign diseases. Among benign diseases,
benign prostatic hyperplasia (BPH) and among malignancies adenocarcinoma are
the most common ones. One of the methods that is used to treat BPH is
transurethral resection (TUR-P). In our study, we investigated incidental tumor
rates observed in patients that have TUR-P due to BPH. We included 120 patients
who underwent TUR-P and whose operation materials were examined in pathology
department between 2014-2016 in our center. Benign diseases were noted in 117
(97.5%) of 120 patients, whereas malignant tumors were detected in 3 (2.5%)
cases. In TUR-P operations performed to relieve symptoms in BPH, adenocarcinoma
is reported in the literature at rates ranging from 4% to 15%. We suggest that patients
with symptoms of prostatism should be carefully investigated, detailed
histopathologic evaluation should be done in terms of incidental tumors and
clinical pathology communication should be at maximum level.

Anahtar Kelimeler

TUR-P, Prostate, Carcinoma, Adenocarcinoma, Incidental, TUR-P

Kaynakça

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• [2] Tutrone, R.F., BalI, R.A., Ornitz, D.M., Leder, P., and Richie, J.P., (1993). Benign Prostatic Hyperpiasia in a Transgenic Mouse: A New Hormonally Sensitive Investigatory Model. J Urol, 149: 633-9.
• [3] Mostofi, F.K., Davis, C.J., and Sesterhenn, I.A., (1992). Pathology of Carcinoma of the Prostate. Cancer 70:235-253.
• [4] Jones, J.S., Follis, H.W., Johnson, J.R., (2009). Probability of Finding T1a and T1b (Incidental) Prostate Cancer during TURP has Decreased in the PSA Era. Pros¬tate Cancer P.D. 12(1):57-60.
• [5] Merrill, R.M. and Wiggins, C.L., (2002). Incidental Detection of Population-Based Prostate Cancer Incidence Rates through Transurethral Resection of the Prostate. Urol Oncol, 7(5):213-9.
• [6] Martino, P., Palazzo, S., Battaglia, M., Lucarelli, G., and Selvagg, F.P., (2004). Incidental Prostatic Cancer: Repeat TURP or Biopsy? Urol Int. 73(3):193-7.
• [7] Yin, M., Bastacky, S., Chandran, U., Becich, M.J., Dhir, R., (2008). Prevalence of Incidental Prostate Cancer in the General Population: A Study of Healthy Organ Donors. J Urol. Mar, 179(3):892-5, discussion 895. doi: 10.1016/j.juro.2007.10.057. Epub 2008 Jan 22.