İnsülin direnci olan hastalarda homosistein düzeylerinin değerlendirilmesi

Yıl 2014, Cilt: 1 Sayı: 2, 30 - 35, 01.09.2014

Ahmet Ahsen Memnune Sena Ulu Akif Acay Erhan Bozkurt Şeref Yüksel

Öz

Anahtar Kelimeler

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İnsülin direnci olan hastalarda homosistein düzeylerinin değerlendirilmesi

Öz

Amaç: İnsülin direnci, hiperhomosisteinemi ve obezite kardiyovasküler hastalıklar için önemli bir risk faktörüdür. Buna rağmen insülin direnci, homosistein düzeyi ve obezite arasındaki ilişki ile ilgili tartışmalar devam etmektedir. Biz çalışmamamızda bu parametreler ve sendromun ilişkisini incelemeyi amaçladık. Gereç ve yöntem: Hastanemize başvurmuş ve tetkikleri yapılmış olan 80 hastanın insülin direnci, homosistein düzeyi, bel kalça oranı (BKO), beden kitle indeksi (BKİ), yağ yüzdesi, rutin biyokimyasal parametreleri kaydedildi. Bulgular: İnsülin direnci olan hastaların homosistein düzeyleri, BKİ ve yağ yüzdeleri insülin direnci olmayanlara göre yüksekti. BKO, açlık kan şekeri, tokluk kan şekeri ve lipid değerleri açısından ise fark yoktu. Sonuç: İnsülin direnci olanlarda kardiyovasküler risk artmış olduğundan, bir başka risk faktörü olarak hiperhomosisteineminin de bulunması bu hastaların daha yakından izlenmesi gerektirdiğini düşündürmektedir

Anahtar Kelimeler

İnsülin direnci, homosistein, obesite

Kaynakça

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