Evaluation of the Differences Between Office and Ambulatory Blood Pressure Values in Children with Structurel Renal Anomaly.

Öz

Structural renal abnormalities are one of the most common causes of hypertension in children. In this study, it was aimed to compare office blood pressure (OBP) and ambulatory blood pressure monitoring  (ABPM) values in children with structural renal abnormalities. The data from patients with structural renal abnormalities who performed ABPM were evaluated in this study. It was investigated whether there were significant differences between OBP and ABPM values. The paired t-test was used to determine the significance of the differences between OBP and ABPM values. The factors affecting the differences between office and ambulatory blood pressure values were investigated using linear regression analysis. The OBP values were significantly higher than nighttime systolic blood pressure (SBP) and diastolic blood pressure (DBP) (p<0.01). The OBP values were positively correlated with all differences (p<0.05). Age and body mass index were positively associated with OBP–nighttime SBP difference (p = 0.001, p = 0.015, respectively). Serum blood urea nitrogen level was positively associated with OBP–nighttime DBP and OBP–24h DBP differences (β = 0.220,  p = 0.033, β = 0.205,  p =  0.045, respectively). There was a negative correlation between glomerul filtration rate and OBP–nighttime SBP difference (β = -0.05,  p = 0.01). The performing of ABPM and the evaluation of the differences between office and ambulatory blood pressure is very important in the early recognition of the hypertension in children with structural renal anomaly.

Anahtar Kelimeler

• Office blood pressure,ambulatory blood pressure,structural renal abnormalities

Yapısal Böbrek Anomalisi olan Çocuklarda Ofis ve Ambulatuvar Kan Basıncı Arasındaki Farklılıkların Değerlendirilmesi

Öz

Yapısal böbrek anomalileri çocukluk döneminde görülen hipertansiyonun en sık nedenlerinden biridir. Bu çalışmada yapısal böbrek anomalisi olan çocuklarda ofis kan basıncı (OKB) ile ambulatuar kan basıncı izlemi (AKBİ) sonuçlarının karşılaştırılması amaçlanmıştır. Bu çalışmada AKBİ yapılan yapısal böbrek anomalili hastaların sonuçları değerlendirildi. Hastaların OKB ile AKBİ değerleri arasında anlamlı farklılık olup olmadığı araştırıldı. OKB ve AKBİ sonuçları arasındaki farklılıkların anlamlılığını belirlemek için t-testi (paired samples t-test) kullanıldı. Farklılıkları etkileyen faktörler lineer regresyon analizi ile araştırıldı.OKB değerleri gece sistolik kan basıncı (SKB) ve diastolik kan basıncı (DKB) değerlerinden anlamlı olarak daha yüksekti (p<0.01). OKB değerleri farklılıkların hepsi ile pozitif korele bulundu (p<0.05). Gece SKB ile OKB arasındaki farklılıklar yaş ve vücut kitle indeksi ile pozitif yönde koreleydi (sırası ile p = 0.001, p = 0.015). Kan üre azotu ile OKB - gece DKB ve OKB - 24 saat DKB farklılıkları arasında anlamlı ilişki olduğu belirlendi (sırası ile β = 0.220,  p = 0.033, β = 0.205,  p =  0.045). Glomerul filtrasyon hızı ve OKB-gece SKB farklılığı arasında anlamlı negatif ilişki olduğu saptandı (β = -0.05,  p = 0.01).  Yapısal böbrek anomalisi olan çocukların izlemi sırasında AKBİ yapılması ve ofis ile ambulatuvar kan basınçları arasındaki farklılıkların değerlendirilmesi hipertansiyonun erken dönemde tanınmasında oldukça önemlidir. 

Anahtar Kelimeler

• Office blood pressure,ambulatory blood pressure,structural renal abnormalities

Kaynakça

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