Pulmoner Tromboemboli ve Nötrofil Albümin Oranı Arasındaki İlişki

Öz

Amaç: Pulmoner tromboemboli (PTE), tüm dünyada sık görülen ve erken tanı ve tedavi gerektiren ciddi bir klinik tablodur. Tanı koymada, hem laboratuvar verileri hem de radyolojik görüntüleme destek sağlamaktadır. Çalışmanın amacı, PTE tanılı hastalarda nötrofil albumin oranının (NAR) klinik önemini araştırmaktır. Gereç ve yöntem: Çalışmaya, PTE tanılı 100 hasta ve sigara içme öyküsü ve komorbidite öyküsü olmayan 50 sağlıklı gönüllü olmak üzere toplam 150 olgu dahil edildi. Tam kan sayımı ve biyokimyasal veriler retrospektif olarak elde edildi. NAR, nötrofilin albumine oranı olarak hesaplandı. Bulgular: Çalışmaya 84’ü erkek (%56) ve 66’sı (%44) kadın olmak üzere toplam 150 vaka dahil edildi. NAR, hasta grubunda istatistiksel olarak anlamlı düzeyde yüksek bulundu (p<0,001). Serum NAR değeri, serum d-dimer değeri ile pozitif korelasyon gösterdi (r:0,488, p<0,001). Sonuç: Yeni, ucuz ve kolay hesaplanabilen bir biyobelirteç olan NAR, PTE hastalarının tanısında yararlı bir parametre olabilir.

Anahtar Kelimeler

• Pulmoner emboli
• Albumin
• Nötrofil
• İnflamasyon

Relationship Between Pulmonary Thromboembolism and Neutrophil Albumin Ratio

Öz

Objective: Pulmonary Thromboembolism (PTE) is a serious clinical condition and is common all over the world, requiring early diagnosis and treatment. Laboratory data and radiological imaging provide support in its diagnosis. The purpose of the present study is to investigate the clinical significance of neutrophil to albumin ratio (NAR) in patients who are diagnosed with PTE. Material and Method: A total of 150 cases who of 100 patients with a diagnosis of PTE and 50 healthy volunteers without a history of smoking or any comorbidities were included in the study. Complete Blood Count (CBC) and biochemical data were evaluated retrospectively. NAR was calculated as the ratio of neutrophil to albumin. Results: A total of 150 cases (84 male (56%) and 66 (44%) female) were included in the study. Neutrophil Albumin Ratio (NAR), were found to be statistically and significantly elevated in the patient group (p<0.001).The Serum NAR value showed a positive correlation with the Serum d-dimer value (r:0.488, p<0.001). Conclusion: It is possible to argue that NAR, which is a novel, cheap, and easily calculable biomarker, can be a useful parameter for the diagnosis of patients with PTE.

Anahtar Kelimeler

• pulmonary embolism
• inflammation
• albumin
• neutrophil

Kaynakça

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