Son Trimester Gebelik ve Gliom : Olgu Sunumu

Öz

Gebelikte semptomatik hale gelen beyin tümörlerinin görülme sıklığı, aynı yaştaki kadınlardakine kıyasla azalmış görülmektedir. Glial hücrelerden kaynaklanan bu tümörler, derecesine bağlı olarak yavaş büyüyen veya agresif ve invaziv olabilen intrinsik parankimal tümörlerdir. Tipik olarak baş ağrısı, bulantı ve kusma gibi nonspesifik semptomlarla ortaya çıkarlar. Gebelikte ortaya çıkan beyin tümörleri hem anne hem fetus için ciddi riskler taşımaktadır. Acil kadın doğuma sancı şikayetiyle başvuran 33 hafta gebe hastanın anamnezinde son 1 ayda her gün epilepsi atakları olduğu öğrenildi. Hastanın daha önceki tetkikleri nöroloji ve nöroşirurjiye danışılarak tekrarlandı ve hastanın sağ temporal bölgede glioblastom saptandı. Gebelikte beyin tümörleri multidisipliner yaklaşılmalı ve tedavisinde hastaya göre hareket edilmelidir.

Anahtar Kelimeler

• gliom,gebelik,beyin tümörü

Last Trimester Pregnancy and Glioma: Case Report

Öz

The incidence of brain tumors that become symptomatic during pregnancy is decreased compared to women of the same age. These tumors originating from glial cells are intrinsic parenchymal tumors that can be slow-growing or aggressive and invasive depending on the degree. They typically present with nonspecific symptoms such as headache, nausea, and vomiting. Brain tumors that occur during pregnancy carry serious risks for both mother and fetus. The 33-week pregnant patient presented to our clinic with the complaint of emergency labor, and it was learned that in her medical history she had epilepsy attacks every day in the last month. Previous examinations of the patient were repeated in consultation with neurology and neurosurgery, and glioblastoma was detected in the right temporal region of the patient. A multidisciplinary approach and treatment of brain tumors during pregnancy should be performed according to the patient.

Anahtar Kelimeler

• glioma,pregnancy,brain tumor

Kaynakça

1. 1. Pregnancy and glial brain tumors Shlomit Yust-Katz, John F. de Groot, Diane Liu, Jimin Wu, Ying Yuan, Mark D. Anderson, Charles A. Conrad, Andrea Milbourne, Mark R. Gilbert, and Terri S. Armstrong. Neuro Oncol. 2014 Sep; 16(9): 1289–1294.
2. 2. Pregnancy-related primary brain and spinal tumors.Roelvink NC, Kamphorst W, van Alphen HA, Rao BR., Arch Neurol. 1987 Feb;44(2):209-15.
3. 3. Challenges of glioma and pregnancy: a systematic review. A. van Westrhenen, J. T. Senders, E. Martin, A. C. Di Risio, and M. L. D. Broekman. J Neurooncol. 2018; 139(1): 1–11.
4. 4. Interactions between glioma and pregnancy: insight from a 52-case multicenter series. Peeters S et al, J Neurosurg. 2018 Jan;128(1):3-13.
5. 5. Sex steroid and growth factor profile of a meningioma associated with pregnancy.Smith JS, Quiñones-Hinojosa A, Harmon-Smith M, Bollen AW, McDermott MW. Can J Neurol Sci. 2005 Feb;32(1):122-7.
6. 6. Influence of pregnancy on glioma patients. Forster MT, Baumgarten P, Gessler F, Maurer G, Senft C, Hattingen E, Seifert V, Harter PN, Franz K. Acta Neurochir (Wien). 2019 Mar;161(3):535-543.