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COVİD-19 HASTALARINDA İŞİTME KAYBI

Year 2022, , 306 - 312, 30.09.2022
https://doi.org/10.17343/sdutfd.1070586

Abstract

Amaç
Dünya çapında bilim insanları, COVID-19'dan iyileşen
hastaları takip etmeye devam ediyorlar. Bu hastalarda
gözlemlenen uzun süreli kalıcı semptomları ve kalıcı
hasarları yayınlıyorlar. Bu çalışma, saf ses odyometrisi
kullanılarak ölçülen saf ses ortalamaları temelinde
COVID-19 hastalarında işitme kaybını değerlendirmeyi
amaçladı.
Gereç ve Yöntem
Bu geriye dönük veri analizi çalışmasında, COVID-
19'lu hastaneye yatırılmamış hastaların saf ses
ortalamaları, COVID-19'a yakalanmadan 1 yıl önce
ve sonra karşılaştırıldı. Sürekli değişkenler ortalama
± standart sapma (SD) olarak, kategorik değişkenler
ise sayı (n) ve yüzde (%) olarak sunuldu. Tüm veriler
normal dağılım gösterdi. Bu nedenle, ölçümler arasındaki
anlamlı farklılıkları belirlemek için bir parametrik
test türü olan eşleştirilmiş t testi kullanılmıştır.
Bulgular
Sol ve sağ kulakların kemik ve hava yollarında ölçülen
saf ses ortalamalarına göre, COVID-19 sonrası
hastaların saf ses eşik değerlerinde anlamlı bir artış
bulundu (tümü için p<0,001). COVID-19 öncesi ve
sonrası sol kulak hava yolunun saf ton ortalamaları
yaşlı erişkinlerde (41-64 yaş) genç yetişkinlere (18-40
yaş) göre daha yüksekti (p=0.040).
Sonuç
COVID-19 her iki kulağın kemik ve hava yollarını etkileyerek
farklı frekanslarda farklı düzeylerde işitme
kaybına neden olmaktadır. COVID-19'un komplikasyonları
üzerine yapılan araştırmalar, işitme kaybı testlerini
içermeli ve olası işitme kaybını önlemek için çalışmalar
yapılmalıdır.

Supporting Institution

yok

Project Number

yok

Thanks

yok

References

  • 1. Li K, Wu J, Wu F, et al. The Clinical and Chest CT Features Associated with Severe and Critical COVID-19 Pneumonia. Invest Radiol.2020;55(6):327-31. doi:10.1097/RLI.0672
  • 2. Ahmad I, Rathore FA. Neurological manifestations and comp- lications of COVID-19: A Literature Review. J ClinNeurosci. 2020;13(5):667-73.doi: 10.1016/j.jiph.2020.03.019
  • 3. Leonardi M, Padovani A, McArthur JC. Neurological manifestations associated with COVID19: a review and a call for action. J Neurol. 2020;267(6):1573-6.
  • 4. Li B, Yang J, Zhao F, et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. ClinRes- Cardiol. 2020;109(5):531‐8. doi:10.1007/s00392-020-01626-9
  • 5. Hunt RH, East JE, Lanas A, et al. COVID-19 and Gastrointestinal Disease: Implications for the Gastroenterologist. Dig- Dis2021;39:119-39. doi: 10.1159/000512152
  • 6. TR. Ministry of Health Covid-19 patients follow-up guide, 2021. Accessed from::https://toraks.org.tr/site/sf/nmf/pre_migration/ 0cd6655ae86e94eec61e88ab75cc757d8eaa1df39ce- 43d3c871b3d715afde5b6.pdf. Accessed time: 05.06.2021
  • 7. Chen X, Fu YY, Zhang TY. Role of Viral infection in sudden hearing loss. J IntMedRes. 2019;47(7):2865–72. doi: 10.1177/0300060519847860.
  • 8. TR. Ministry of Family, Laborand Social Security. Health and surve illance guide in working life, 2018. Accessed from: https:// www.ailevecalisma.gov.tr/medias/4591/rehber03.pdf. Accessed time: 05.06.2021
  • 9. Mustafa MW. Audiological profile of asymptomatic Covid-19 PCR-positive cases. Am J Otolaryngol. 2020;41(3) doi: 10.1016/j.amjoto.2020.102483.
  • 10. Karimi-Galougahi M, Naeini AS, Raad N, et al. Vertigo and hearing loss during the COVID-19 pandemic - is there an association? ActaOtorhinolaryngolItal. 2020;40:463-5. doi: 10.14639/0392-100X-N0820
  • 11. Koumpa FS, Forde CT, Manjaly JG. Sudden irreversible hearing loss post COVID-19. BMJ Case Reports CP 2020;13,13(11):e238419 doi:10.1136/bcr-2020-238419.
  • 12. Sriwijitalai W, Wiwanitkit V. Hearing loss and COVID-19: A note. AmericanJournal of Otolaryngology -Head and Neck Medicine and Surgery;2020;41(3). doi:10.1016/j.amjoto.2020.102473
  • 13. Han W, Quan B, Guo Y, et al. The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019. Journal of Medical Virology.2020;92(5):461-3. doi:10.1002/ jmv.25711
  • 14. Kim J, Jung J, Moon IS, Lee HK, Lee WS. Statistical analysis of puretone audiometry and caloric test in herpes zosteroticus. ClinExpOtorhinolaryngol. 2008;1(1):15-9.
  • 15. Kim CH, Choi H, Shin JE. Characteristics of hearing loss in patients with herpes zosteroticus. Medicine (Baltimore). 2016;95(46):e5438.
  • 16. Acharya A, Kevadiya BD, Gendelman HE, Byrareddy SN. SARSCoV- 2 Infection Leads to Neurological Dysfunction. J NeuroimmunePharmacol2020; 15:167–73.
  • 17. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, vanGoor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004;203(2):631-7. doi: 10.1002/ path.1570.
  • 18. Iroegbu JD, Ifenatuoha CW. Ijomone OM. Potential neurological impact of coronaviruses: implications for the novel SARSCoV- 2. NeurolSci. 2020;41(6):1329-37.
  • 19. Kalcioglu MT, Cag Y, Kilic O, Tuysuz O. COVID-19 cause sudden sensorineural hearing loss? Int J Infect Dis.2020;101:205 doi:10.1016/j.ijid.2020.09.1468.
  • 20. Maharaj S, BelloAlvarez M, Mungul S, Hari K. Otologic dysfunction in patients with COVID-19: a systematic review. LaryngoscopeInvestigOtolaryngol.2020;5(6):1192–6. doi: 10.1002/ lio2.498.
  • 21. Saniasiaya J. Hearing loss in SARS-CoV-2: What do we know? EarNoseThroat J. 2020;100(2):152-4. doi: 10.1177/0145561320946902.
  • 22. Taneja MK. Deafness in COVID-19. Indian J Otol. 2020;26(2):68- 70 doi:10.4103/indianjotol.INDIANJOTOL_83_20
  • 23. Yaseen N K, Al-Ani R M, Ali Rashid R. COVID-19-related sudden sensorineural hearing loss. Qatar medical journal, 2021(3), 58. https://doi.org/10.5339/qmj.2021.58
  • 24. Edwards M, Muzaffar J, Naik P, Coulson C. Catastrophic bilateral sudden sensorineural hearing loss following COVID-19. BMJ Case Rep. 2021 ;14(6):e243157. doi: 10.1136/bcr-2021- 243157.
  • 25. 25. Koumpa F S, Forde C T, Manjaly J G. Sudden irreversible hearing loss post COVID-19. BMJ case reports 2020;13(11); e238419. https://doi.org/10.1136/bcr-2020-238419

HEARING LOSS IN PATIENTS WITH COVID-19

Year 2022, , 306 - 312, 30.09.2022
https://doi.org/10.17343/sdutfd.1070586

Abstract

Objective
Worldwide, scientists continue to follow-up on patients
recovered from COVID-19 and have published the
long-term persistent symptoms and permanent
damage observed in various tissues. The present
study aimed to evaluate hearing loss in patients
with COVID-19 on the basis of pure tone averages
measured using pure tone audiometry.
Material and Method
In this retrospective data analysis study, pure
tone averages of non-hospitalised patients with
COVID-19 were compared over 1 year before and
after contracting COVID-19. Continuous variables
were presented as mean ± Standard deviation
(SD) and categorical variables were presented as
number (n) and percentage (%). All data showed
normal distribution. Therefore, paired t-test, a type of
parametric test, was used to identify the significant
differences between the measurements.
Results
The pure tone threshold values of patients increased
significantly after COVID-19 (p0.001 for all) based on
puretone averages measured in the bones and airways
of theleftandrightears. Olderadults (41–64 yearsold)
had a greater difference in puretone averages of the
left ear airway before and after COVID-19 (p=0.040)
than younger adults (18–40 yearsold).
Conclusion
COVID-19 affects both ears' bones and airways,
causing varying degrees of hearing loss at different
frequencies. Hearing loss tests should be included
in COVID-19 complications research, and clinicians
should be given advice on how to avoid hearing loss.

Project Number

yok

References

  • 1. Li K, Wu J, Wu F, et al. The Clinical and Chest CT Features Associated with Severe and Critical COVID-19 Pneumonia. Invest Radiol.2020;55(6):327-31. doi:10.1097/RLI.0672
  • 2. Ahmad I, Rathore FA. Neurological manifestations and comp- lications of COVID-19: A Literature Review. J ClinNeurosci. 2020;13(5):667-73.doi: 10.1016/j.jiph.2020.03.019
  • 3. Leonardi M, Padovani A, McArthur JC. Neurological manifestations associated with COVID19: a review and a call for action. J Neurol. 2020;267(6):1573-6.
  • 4. Li B, Yang J, Zhao F, et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. ClinRes- Cardiol. 2020;109(5):531‐8. doi:10.1007/s00392-020-01626-9
  • 5. Hunt RH, East JE, Lanas A, et al. COVID-19 and Gastrointestinal Disease: Implications for the Gastroenterologist. Dig- Dis2021;39:119-39. doi: 10.1159/000512152
  • 6. TR. Ministry of Health Covid-19 patients follow-up guide, 2021. Accessed from::https://toraks.org.tr/site/sf/nmf/pre_migration/ 0cd6655ae86e94eec61e88ab75cc757d8eaa1df39ce- 43d3c871b3d715afde5b6.pdf. Accessed time: 05.06.2021
  • 7. Chen X, Fu YY, Zhang TY. Role of Viral infection in sudden hearing loss. J IntMedRes. 2019;47(7):2865–72. doi: 10.1177/0300060519847860.
  • 8. TR. Ministry of Family, Laborand Social Security. Health and surve illance guide in working life, 2018. Accessed from: https:// www.ailevecalisma.gov.tr/medias/4591/rehber03.pdf. Accessed time: 05.06.2021
  • 9. Mustafa MW. Audiological profile of asymptomatic Covid-19 PCR-positive cases. Am J Otolaryngol. 2020;41(3) doi: 10.1016/j.amjoto.2020.102483.
  • 10. Karimi-Galougahi M, Naeini AS, Raad N, et al. Vertigo and hearing loss during the COVID-19 pandemic - is there an association? ActaOtorhinolaryngolItal. 2020;40:463-5. doi: 10.14639/0392-100X-N0820
  • 11. Koumpa FS, Forde CT, Manjaly JG. Sudden irreversible hearing loss post COVID-19. BMJ Case Reports CP 2020;13,13(11):e238419 doi:10.1136/bcr-2020-238419.
  • 12. Sriwijitalai W, Wiwanitkit V. Hearing loss and COVID-19: A note. AmericanJournal of Otolaryngology -Head and Neck Medicine and Surgery;2020;41(3). doi:10.1016/j.amjoto.2020.102473
  • 13. Han W, Quan B, Guo Y, et al. The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019. Journal of Medical Virology.2020;92(5):461-3. doi:10.1002/ jmv.25711
  • 14. Kim J, Jung J, Moon IS, Lee HK, Lee WS. Statistical analysis of puretone audiometry and caloric test in herpes zosteroticus. ClinExpOtorhinolaryngol. 2008;1(1):15-9.
  • 15. Kim CH, Choi H, Shin JE. Characteristics of hearing loss in patients with herpes zosteroticus. Medicine (Baltimore). 2016;95(46):e5438.
  • 16. Acharya A, Kevadiya BD, Gendelman HE, Byrareddy SN. SARSCoV- 2 Infection Leads to Neurological Dysfunction. J NeuroimmunePharmacol2020; 15:167–73.
  • 17. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, vanGoor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol. 2004;203(2):631-7. doi: 10.1002/ path.1570.
  • 18. Iroegbu JD, Ifenatuoha CW. Ijomone OM. Potential neurological impact of coronaviruses: implications for the novel SARSCoV- 2. NeurolSci. 2020;41(6):1329-37.
  • 19. Kalcioglu MT, Cag Y, Kilic O, Tuysuz O. COVID-19 cause sudden sensorineural hearing loss? Int J Infect Dis.2020;101:205 doi:10.1016/j.ijid.2020.09.1468.
  • 20. Maharaj S, BelloAlvarez M, Mungul S, Hari K. Otologic dysfunction in patients with COVID-19: a systematic review. LaryngoscopeInvestigOtolaryngol.2020;5(6):1192–6. doi: 10.1002/ lio2.498.
  • 21. Saniasiaya J. Hearing loss in SARS-CoV-2: What do we know? EarNoseThroat J. 2020;100(2):152-4. doi: 10.1177/0145561320946902.
  • 22. Taneja MK. Deafness in COVID-19. Indian J Otol. 2020;26(2):68- 70 doi:10.4103/indianjotol.INDIANJOTOL_83_20
  • 23. Yaseen N K, Al-Ani R M, Ali Rashid R. COVID-19-related sudden sensorineural hearing loss. Qatar medical journal, 2021(3), 58. https://doi.org/10.5339/qmj.2021.58
  • 24. Edwards M, Muzaffar J, Naik P, Coulson C. Catastrophic bilateral sudden sensorineural hearing loss following COVID-19. BMJ Case Rep. 2021 ;14(6):e243157. doi: 10.1136/bcr-2021- 243157.
  • 25. 25. Koumpa F S, Forde C T, Manjaly J G. Sudden irreversible hearing loss post COVID-19. BMJ case reports 2020;13(11); e238419. https://doi.org/10.1136/bcr-2020-238419
There are 25 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Articles
Authors

Gökmen Özceylan 0000-0002-2388-4158

Dilek Toprak 0000-0001-5119-9089

Project Number yok
Publication Date September 30, 2022
Submission Date February 13, 2022
Acceptance Date April 7, 2022
Published in Issue Year 2022

Cite

Vancouver Özceylan G, Toprak D. HEARING LOSS IN PATIENTS WITH COVID-19. Med J SDU. 2022;29(3):306-12.

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